A phase I study of the CDK4/6 inhibitor ribociclib combined with gemcitabine in patients with advanced solid tumors

Authors: Aurora Norman, Mahesh Seetharam, Jacob Allred, Jianping Kong, Mateusz Opyrchal, Wen Wee Ma, Yanyan Lou, Grace K. Dy, Amit Mahipal, S. John Weroha, Andrea E. Wahner Hendrickson, Joel M. Reid, Alex A. Adjei

Source: BJC Reports, Vol 3, Iss 1, Pp 1-8 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2731-9377

Access URL: https://doaj.org/article/fda9e4c37b2544cb91d18418d44b5d41

A phase 2 and pharmacological study of sapanisertib in patients with relapsed and/or refractory acute lymphoblastic leukemia

Authors: Aref Al‐Kali, Ibrahim Aldoss, Pamela J. Atherton, Carrie A. Strand, Bijal Shah, Jonathan Webster, Bhavana Bhatnagar, Karen S. Flatten, Kevin L. Peterson, Paula A. Schneider, Sarah A. Buhrow, Jianping Kong, Joel M. Reid, Alex A. Adjei, Scott H. Kaufmann

Source: Cancer Medicine, Vol 12, Iss 23, Pp 21229-21239 (2023)

Subject Terms: acute lymphoblastic leukemia, ALL, mTOR inhibitor, sapanisertib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/55ca42b54be149f0b8acb389ece68dc9

A challenging case of stage IV EGFR-mutant lung cancer with histologic transformation and multiple resistance mechanisms

Authors: Joel Rivera-Concepcion, Ying-Chun Lo, Dipesh Uprety, Alex A. Adjei, Vinicius Ernani, Konstantinos Leventakos

Source: Current Problems in Cancer: Case Reports, Vol 13, Iss , Pp 100284- (2024)

Subject Terms: NSCLC, EGFR mutation, Histologic transformation, Acquired resistance, Neuroendocrine cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666621924000073; https://doaj.org/toc/2666-6219

Access URL: https://doaj.org/article/89b01e3fc5fe4031b3866f1dd44b3b45

Our Work Is Done, and You Are in Good Hands

Authors: Alex A. Adjei, MD, PhD

Source: JTO Clinical and Research Reports, Vol 4, Iss 1, Pp 100447- (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666364322001710; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/8ae9217b682e499d9b4f68ab8639051f

Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers

Authors: Tara L. Hogenson, Hao Xie, William J. Phillips, Merih D. Toruner, Jenny J. Li, Isaac P. Horn, Devin J. Kennedy, Luciana L. Almada, David L. Marks, Ryan M. Carr, Murat Toruner, Ashley N. Sigafoos, Amanda N. Koenig-Kappes, Rachel L.O. Olson, Ezequiel J. Tolosa, Cheng Zhang, Hu Li, Jason D. Doles, Jonathan Bleeker, Michael T. Barrett, James H. Boyum, Benjamin R. Kipp, Amit Mahipal, Joleen M. Hubbard, Temperance J. Scheffler Hanson, Gloria M. Petersen, Surendra Dasari, Ann L. Oberg, Mark J. Truty, Rondell P. Graham, Michael J. Levy, Mojun Zhu, Daniel D. Billadeau, Alex A. Adjei, Nelson Dusetti, Juan L. Iovanna, Tanios S. Bekaii-Saab, Wen Wee Ma, Martin E. Fernandez-Zapico

Source: JCI Insight, Vol 7, Iss 22 (2022)

Subject Terms: Oncology, Therapeutics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/f973dfbdbe53458f81a1c8da0742e768

Efficacy of immune checkpoint inhibitors in non-small cell lung cancer: A systematic review and meta-analysis

Authors: Fang Yang, Yucai Wang, Lin Tang, Aaron Scott Mansfield, Alex A. Adjei, Konstantinos Leventakos, Narjust Duma, Jia Wei, Lifeng Wang, Baorui Liu, Julian R. Molina

Source: Frontiers in Oncology, Vol 12 (2022)

Subject Terms: non-small cell lung cancer, immune checkpoint inhibitor, efficacy, survival, meta-analysis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2022.955440/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/c8ad526a23f0433695f64c792fc2a9e0

Inflation of tumor mutation burden by tumor-only sequencing in under-represented groups

Authors: Yan W. Asmann, Kaushal Parikh, P. Leif Bergsagel, Haidong Dong, Alex A. Adjei, Mitesh J. Borad, Aaron S. Mansfield

Source: npj Precision Oncology, Vol 5, Iss 1, Pp 1-4 (2021)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/953d0fc861874af3a5542c24c24ac1b0

Survival of Black and White Patients With Stage IV Small Cell Lung Cancer

Authors: Huashan Shi, Kexun Zhou, Jordan Cochuyt, David Hodge, Hong Qin, Rami Manochakian, Yujie Zhao, Sikander Ailawadhi, Alex A. Adjei, Yanyan Lou

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: stage IV Small cell lung cancer, racial, socioeconomic status, survival, academic program, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.773958/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/e82b721c7a4c41e99e514d7a49a1f78f

JTO Clinical and Research Reports Is Born

Authors: Alex A. Adjei, MD, PhD

Source: JTO Clinical and Research Reports, Vol 1, Iss 1, Pp 100014- (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S266636432030014X; https://doaj.org/toc/2666-3643

Access URL: https://doaj.org/article/1614ef55a3f246a391b40295433939c6

Farnesyltransferase inhibitor tipifarnib inhibits Rheb prenylation and stabilizes Bax in acute myelogenous leukemia cells

Authors: Husheng Ding, Jennifer S. McDonald, Seongseok Yun, Paula A. Schneider, Kevin L. Peterson, Karen S. Flatten, David A. Loegering, Ann L. Oberg, Shaun M. Riska, Shengbing Huang, Frank A. Sinicrope, Alex A. Adjei, Judith E. Karp, X. Wei Meng, Scott H. Kaufmann

Source: Haematologica, Vol 99, Iss 1 (2014)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/6906; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/c8ce24c260924fff83b4f73d3d068613

In the clinic: ongoing clinical trials evaluating c-MET-inhibiting drugs

Authors: Neelesh Sharma, Alex A. Adjei

Source: Therapeutic Advances in Medical Oncology, Vol 3 (2011)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1758-8340; https://doaj.org/toc/1758-8359

Access URL: https://doaj.org/article/5e5b24d4dd02434d9292f6847a3565f5

Phase I and pharmacological study of cytarabine and tanespimycin in relapsed and refractory acute leukemia

Authors: Scott H. Kaufmann, Judith E. Karp, Mark R. Litzow, Ruben A. Mesa, William Hogan, David P. Steensma, Karen S. Flatten, David A. Loegering, Paula A. Schneider, Kevin L. Peterson, Matthew J. Maurer, B. Douglas Smith, Jacqueline Greer, Yuhong Chen, Joel M. Reid, S. Percy Ivy, Matthew M. Ames, Alex A. Adjei, Charles Erlichman, Larry M. Karnitz

Source: Haematologica, Vol 96, Iss 11 (2011)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/6120; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/f7f7717a6c364771a1cbefbdd5f290b1

Service Quality Affecting Student Satisfaction in Higher Education Institutions in Ghana

Authors: George Kofi Amoako, George Oppong Ampong, Antoinette Yaa Benewaa Gabrah (ORCID 0000-0003-2980-6000), Felicia de Heer, Alex Antwi-Adjei

Source: Cogent Education. 2023 10(2).

Peer Reviewed: Y

Page Count: 18

Descriptors: Foreign Countries, Student Satisfaction, College Students, Educational Quality, Academic Support Services, Services, College Administration, Evidence

Geographic Terms: Ghana

The value of combined‐modality therapy in elderly patients with stage III nonsmall cell lung cancer.

Authors: Steven E. Schild, Sumithra J. Mandrekar, Aminah Jatoi, William L. McGinnis, Phillip J. Stella, Richard L. Deming, James R. Jett, Yolanda I. Garces, Katie L. Allen, Alex A. Adjei

Source: Cancer (0008543X); Jul2007, Vol. 110 Issue 2, p363-368, 6p

Subject Terms: LUNG cancer, CANCER cells, DRUG therapy, MEDICAL radiology, CLINICAL trials

A phase II study of bortezomib in the treatment of metastatic malignant melanoma.

Authors: Svetomir N. Markovic, Susan M. Geyer, Fitzroy Dawkins, William Sharfman, Mark Albertini, William Maples, Paula M. Fracasso, Tom Fitch, Patricia LoRusso, Alex A. Adjei, Charles Erlichman

Source: Cancer (0008543X); Jun2005, Vol. 103 Issue 12, p2584-2589, 6p

Results of combined‐modality therapy for limited‐stage small cell lung carcinoma in the elderlyAdditional participating institutions include the following: Duluth CCOP, Duluth, MN (Daniel A. Nikcevich, M.D.); Cedar Rapids Oncology Project CCOP, Cedar Rapids, IA (Martin Wiesenfeld, M.D.); Meritcare Hospital CCOP, Fargo, ND (Ralph Levitt, M.D.); Toledo Community Hospital Oncology Program CCOP, Toledo, OH (Paul L. Schaefer, M.D.); Sioux Community Cancer Consortium, Sioux Falls, SD (Loren K. Tschetter, M.D.); Geisinger Clinical Oncology Program, Danville, PA (Suresh Nair, M.D.); Rapid City Regional Oncology Group, Rapid City, SD (Larry P. Ebbert, M.D.); Saskatoon Cancer Center, Saskatoon, Saskatchewan, Canada and Allan Blair Cancer Centre, Regina, Saskatchewan, Canada (Muhammad Salim, M.D.); Scottsdale CCOP, Scottsdale, AZ (Tom R. Fitch, M.D.); Carle Cancer Center CCOP, Urbana, IL (Kendrith M. Rowland, M.D.); Medcenter One Health Systems, Bismarck, ND (Ferdinand Addo, M.D.); Altru Health S

Authors: Steven E. Schild, Philip J. Stella, Burke J. Brooks, Sumithra Mandrekar, James A. Bonner, William L. McGinnis, James A. Mailliard, James E. Krook, Richard L. Deming, Alex A. Adjei, Aminah Jatoi, James R. Jett

Source: Cancer (0008543X); Jun2005, Vol. 103 Issue 11, p2349-2354, 6p

729 A first-in-human, open-label, multicenter, phase 1/2a, dose escalation and expansion study of GI-102, a novel immunocytokine combining CD80-IL2v3, in patients with advanced or metastatic solid tumors

Authors: Kyungwha Lee, Jeeyun Lee, Mahesh Seetharam, Jae Lyun Lee, Jung-Yun Lee, Byoung Chul Cho, Myoung Ho Jang, Yujie Zhao, Nari Yun, Alex A Adjei, Chong Woo Park, Jian L Campian, Wen Wee Ma, Dongwoo Chae, Woosun Lee, Wooyul Lee, Sosun Park, Bochan Seo

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/bade833e049342d5b94d87b5f5d30fab

Dual checkpoint targeting of B7-H3 and PD-1 with enoblituzumab and pembrolizumab in advanced solid tumors: interim results from a multicenter phase I/II trial

Authors: Xiaoyu Zhang, Anthony M Joshua, Sanjeev Kaul, Scott Antonia, Robert L Ferris, Roger B Cohen, Ezio Bonvini, Jan Baughman, Victoria Atkinson, Charu Aggarwal, Nicholas Vogelzang, Osama Rahma, Mahesh Seetharam, Yanyan Lou, Anthony Tolcher, Fernanda I Arnaldez, Amy Prawira, Ralph Hauke, Vinod Ganju, Andrew Weickhardt, Dan P Zandberg, Arash Rezazadeh Kalebasty, Alex A Adjei, Ariel Birnbaum, Rosetta Cavallo, Linda Peng, Paul A Moore, Stacie M Goldberg, Nehal J Lakhani

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/4/e004424.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/195a4377dadb4e879675192629df7c9e

Disclosure, Accountability and Performance: The Case of Ghanaian Banking Industry

Authors: Alex Antwi-Adjei, Kong Yusheng, Samuel Asubonteng

Source: International Journal of Management, Accounting and Economics, Vol 6, Iss 12, Pp 844-861 (2019)

Subject Terms: disclosure, accountability, performance, financial sector, Business, HF5001-6182

File Description: electronic resource

Relation: https://www.ijmae.com/article_114656_9b9aca4059a729fff66eeb4d0caba74f.pdf; https://doaj.org/toc/2383-2126

Access URL: https://doaj.org/article/6aade71aea494a6cb04687dfeab19f56

Oncologists' reflections on patient rights and access to compassionate use drugs: A qualitative interview study from an academic cancer center.

Authors: Jeremiah Stout, Cambray Smith, Jan Buckner, Alex A Adjei, Mark Wentworth, Jon C Tilburt, Zubin Master

Source: PLoS ONE, Vol 16, Iss 12, p e0261478 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0261478&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/e8ac8f53add34504ab1f6b3734d68c9c