The eEF2 kinase coordinates the DNA damage response to cisplatin by supporting p53 activation

Authors: Jonathan K. M. Lim, Arash Samiei, Alberto Delaidelli, Jessica Oliveira de Santis, Vanessa Brinkmann, Christopher J. Carnie, Daniel Radiloff, Laura Hruby, Alisa Kahler, Jordan Cran, Gabriel Leprivier, Poul H. Sorensen

Source: Cell Death and Disease, Vol 15, Iss 7, Pp 1-10 (2024)

Subject Terms: Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2041-4889

Access URL: https://doaj.org/article/6835837b84d7441fa2ee38d01cd997d9

Transcriptional immunogenomic analysis reveals distinct immunological clusters in paediatric nervous system tumours

Authors: Arash Nabbi, Pengbo Beck, Alberto Delaidelli, Derek A. Oldridge, Sumedha Sudhaman, Kelsey Zhu, S. Y. Cindy Yang, David T. Mulder, Jeffrey P. Bruce, Joseph N. Paulson, Pichai Raman, Yuankun Zhu, Adam C. Resnick, Poul H. Sorensen, Martin Sill, Sebastian Brabetz, Sander Lambo, David Malkin, Pascal D. Johann, Marcel Kool, David T. W. Jones, Stefan M. Pfister, Natalie Jäger, Trevor J. Pugh

Source: Genome Medicine, Vol 15, Iss 1, Pp 1-24 (2023)

Subject Terms: Paediatric neuro-oncology, Immunogenomics, CNS tumours, Tumour microenvironment, Neuroblastoma, Medicine, Genetics, QH426-470

File Description: electronic resource

Relation: https://doaj.org/toc/1756-994X

Access URL: https://doaj.org/article/55f18503cc5b446bb5969c8df01fb686

Pediatric Brain Tumours: Lessons from the Immune Microenvironment

Authors: Betty Yao, Alberto Delaidelli, Hannes Vogel, Poul H. Sorensen

Source: Current Oncology, Vol 30, Iss 5, Pp 5024-5046 (2023)

Subject Terms: tumour immune microenvironment, pediatric brain tumour, immunotherapy, medulloblastoma, pediatric high-grade glioma, tumour-infiltrating lymphocytes, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.mdpi.com/1718-7729/30/5/379; https://doaj.org/toc/1198-0052; https://doaj.org/toc/1718-7729

Access URL: https://doaj.org/article/d3be6e31314e401f98284991090f1880

Recent Advances in the Diagnosis and Treatment of Brain Tumors

Authors: Alberto Delaidelli, Alessandro Moiraghi

Source: Brain Sciences, Vol 14, Iss 3, p 224 (2024)

Subject Terms: n/a, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/14/3/224; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/6d1139b9cea34cd1aa16641eef6d84e2

α-Synuclein pathology in Parkinson disease activates homeostatic NRF2 anti-oxidant response

Authors: Alberto Delaidelli, Mette Richner, Lixiang Jiang, Amelia van der Laan, Ida Bergholdt Jul Christiansen, Nelson Ferreira, Jens R. Nyengaard, Christian B. Vægter, Poul H. Jensen, Ian R. Mackenzie, Poul H. Sorensen, Asad Jan

Source: Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)

Subject Terms: Parkinson disease, Alpha-synuclein, Oxidative stress, NRF2, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/4556178dc7c94ccab3861fb11cbb6d65

Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors

Authors: David M Barrett, Daniel Martinez, Tiffany Smith, Jessica B Foster, Crystal Griffin, Jo Lynne Rokita, Allison Stern, Cameron Brimley, Komal Rathi, Maria V Lane, Samantha N Buongervino, Peter J Madsen, Alberto Delaidelli, Poul H Sorensen, Robert J Wechsler-Reya, Katalin Karikó, Phillip B Storm, Adam C Resnick, John M Maris, Kristopher R Bosse

Source: Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/10/9/e004450.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/e7606fcfe47343a78a08e0f4943daef3

RNA modifications in brain tumorigenesis

Authors: Albert Z. Huang, Alberto Delaidelli, Poul H. Sorensen

Source: Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-13 (2020)

Subject Terms: Brain tumors, mRNA modifications, Glioma, Post-translational modifications, Alternative splicing, Alternative polyadenylation (APA), Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-020-00941-6; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/5d999905df4941b79cf6ea5bb4182571

Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity

Authors: Asad Jan, Brandon Jansonius, Alberto Delaidelli, Forum Bhanshali, Yi Andy An, Nelson Ferreira, Lisa M. Smits, Gian Luca Negri, Jens C. Schwamborn, Poul H. Jensen, Ian R. Mackenzie, Stefan Taubert, Poul H. Sorensen

Source: Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)

Subject Terms: eEF2K, Parkinson disease, Alpha synuclein, Oxidative stress, Neurotoxicity, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40478-018-0554-9; https://doaj.org/toc/2051-5960

Access URL: https://doaj.org/article/e23110f14d4a4b2fa31d3af3eb5018a9

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