Clinical Validation of the TruSight Oncology 500 Assay for the Detection and Reporting of Pan-Cancer Biomarkers

Authors: Al-Kateb, Hussam ^{∗, ∗}, Knight, Shannon M. ^∗, Sivasankaran, Gopinath ^†, Voss, Jesse S. ^∗, Pitel, Beth A. ^∗, Blommel, Joseph H. ^∗, Jerde, Calvin R. ^∗, Rumilla, Kandeleria M. ^∗, Lee, Jodi L. ^∗, Mattson, Nate R. ^∗, Lauer, Kim P. ^†, Zimmerman Zuckerman, Eric A. ^∗, Hofich, Chris D. ^∗, Milosevic, Dragana ^∗, Thompson, Joe ^∗, Tillmans, Lori S. ^∗, Stai, Tony T. ^∗, Dasari, Surendra ^†, Pryzbylski, Amber L. ^∗, Mullineaux, Lisa G. ^∗, Ida, Cris M. ^∗, Jenkins, Robert B. ^∗, Gupta, Sounak ^∗, Kipp, Benjamin R. ^∗, Halling, Kevin C. ^{∗, ∗}

Source: In The Journal of Molecular Diagnostics January 2025

NTRK3 -Rearranged Prostatic Acinar Adenocarcinoma: Report of a Patient and Review of the Literature.

Authors: Whaley, Rumeal D., Tekin, Burak, McCarthy, Michael R., Zia, Hamid M., Pitel, Beth A., Al-Kateb, Hussam, Cheville, John C., Gupta, Sounak

Source: International Journal of Surgical Pathology; Feb2025, Vol. 33 Issue 1, p204-208, 5p

Subject Terms: GENE fusion, GENE rearrangement, PROSTATE cancer, INDIVIDUALIZED medicine, ADENOCARCINOMA

Testicular sclerosing stromal tumour: A report of two cases documenting GLI1 alterations.

Authors: Whaley, Rumeal D, Herrera Hernandez, Loren P, Tekin, Burak, McCarthy, Michael R, Hofich, Christopher D, Al‐Kateb, Hussam, Halling, Kevin C, Gupta, Sounak, Hornick, Jason L, Ulbright, Thomas M

Source: Histopathology; Nov2024, Vol. 85 Issue 5, p829-832, 4p

Subject Terms: SOFT tissue tumors, TESTIS tumors, TESTICULAR cancer, ZINC-finger proteins, GENE fusion, GENE amplification, SPERMATOGENESIS

Ovarian epithelioid tumor with FUS::CREM fusion and multilineage protein expression: Report of a case in the EWSR1/FUS-CREB tumor spectrum

Authors: Schoolmeester, J. Kenneth ^a, Gupta, Sounak ^b, Boland, Jennifer M. ^b, Al Kateb, Hussam ^c, Swanson, Amy A. ^{b, ⁎}

Source: In Human Pathology January 2025 155

Intragenic CNTN4 copy number variants associated with a spectrum of neurobehavioral phenotypes

Authors: Zhang, Stephanie Q., Fleischer, Julie, Al-Kateb, Hussam, Mito, Yoshiko, Amarillo, Ina, Shinawi, Marwan

Source: In European Journal of Medical Genetics March 2020 63(3)

Future of Personalized Therapy Targeting Aberrant Signaling Pathways in Multiple Myeloma

Authors: Anwer, Faiz, Gee, Kevin Mathew, Iftikhar, Ahmad, Baig, Mirza, Russ, Atlantis Dawn, Saeed, Sabina, Zar, Muhammad Abu, Razzaq, Faryal, Carew, Jennifer, Nawrocki, Steffan, Al-Kateb, Hussam, Cavalcante Parr, Nadia Nunes, McBride, Ali, Valent, Jason, Samaras, Christy

Source: In Clinical Lymphoma, Myeloma and Leukemia July 2019 19(7):397-405

Expanding the spectrum of fusion partners for cystic TFE3-rearranged renal cell carcinomas: A report of a MAPK1IP1L::TFE3-rearranged renal cell carcinoma

Authors: Tekin, Burak, Chen, Ruqin, Whaley, Rumeal D., Reynolds, Jordan P., Al-Kateb, Hussam, Cheville, John C., Gupta, Sounak

Source: In Human Pathology November 2024 153

Unexpected favorable outcome in a patient with high grade B-cell lymphoma with abnormalities of MYC, BCL6 and BCL2 loci

Authors: Adams, Thomas, Fuchs, Deborah, Shadoan, Patricia K, Johnstone, Laurel, Lau, Branden M, McGhan, Lee, Anwer, Faiz, Al-Kateb, Hussam

Source: In Cancer Genetics April 2018 222-223:25-31

P711: PMS2 in somatic oncology testing: Real or pseudogene interference?

Authors: Waltman, Lindsey, Rumilla, Kandelaria, Al Kateb, Hussam

Source: In Genetics in Medicine Open 2024 2 Supplement 1

CAMTA1‐related disorder: Phenotypic and molecular characterization of 26 new individuals and literature review.

Authors: Al‐Kateb, Hussam¹ (AUTHOR), Au, P. Y. Billie² (AUTHOR), Berland, Siren³ (AUTHOR), Cogne, Benjamin⁴ (AUTHOR), Demurger, Florence⁵ (AUTHOR), Fluss, Joel⁶ (AUTHOR), Isidor, Bertrand⁴ (AUTHOR), Frank, L. Matthew⁷ (AUTHOR), Varvagiannis, Konstantinos⁶ (AUTHOR), Koolen, David A.⁸ (AUTHOR), McDonald, Marie⁹ (AUTHOR), Montgomery, Sarah⁹ (AUTHOR), Moortgat, Stéphanie¹⁰ (AUTHOR), Deprez, Marie¹⁰ (AUTHOR), Karadurmus, Deniz¹⁰ (AUTHOR), Paulsen, Julie³ (AUTHOR), Reis, André¹¹ (AUTHOR), Rieger, Melissa¹¹ (AUTHOR), Vasileiou, Georgia¹¹ (AUTHOR), Willing, Marcia¹² (AUTHOR)

Source: Clinical Genetics. Mar2024, Vol. 105 Issue 3, p294-301. 8p.

Identification of major factors associated with failed clinical molecular oncology testing performed by next generation sequencing (NGS)

Authors: Al-Kateb, Hussam, Nguyen, TuDung T., Steger-May, Karen, Pfeifer, John D.

Source: In Molecular Oncology November 2015 9(9):1737-1743

69. Efficient clinical review of complex NGS tumor copy number profiles using ACMG/CGC guidelines and an interactive web app

Authors: Chen, Ellen, Wang, Jinlian, Kueffner, Robert, Al-Kateb, Hussam, Silkov, Antonina, Uzilov, Andrew, Lochovsky, Lucas, Li, Hui, Newman, Scott

Source: In Cancer Genetics November 2023 278-279 Supplement 1

Association of Li-Fraumeni Syndrome With Small Cell Carcinoma of the Ovary, Hypercalcemic Type and Concurrent Pleomorphic Liposarcoma of the Cervix

Authors: Tandon, Bevan, Hagemann, Ian S., Maluf, Horacio M., Pfeifer, John D., Al-Kateb, Hussam

Source: International journal of gynecological pathology. 36(6):593-599

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100049653744.0x000001&indx=1&recIds=ETOCvdc_100049653744.0x000001

53. Clinical whole exome/whole transcriptome (WES/WTS) analysis detects copy number and structural rearrangements important

Authors: Al-Kateb, Hussam

Source: Cancer genetics. 268(S1):17-18

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176328308.0x000001&indx=1&recIds=ETOCvdc_100176328308.0x000001

Detection of Gene Rearrangements in Targeted Clinical Next-Generation Sequencing

Authors: Abel, Haley J., Al-Kateb, Hussam, Cottrell, Catherine E., Bredemeyer, Andrew J., Pritchard, Colin C., Grossmann, Allie H., Wallander, Michelle L., Pfeifer, John D., Lockwood, Christina M., Duncavage, Eric J.

Source: In The Journal of Molecular Diagnostics July 2014 16(4):405-417

Validation of a Next-Generation Sequencing Assay for Clinical Molecular Oncology

Authors: Cottrell, Catherine E., Al-Kateb, Hussam, Bredemeyer, Andrew J., Duncavage, Eric J., Spencer, David H., Abel, Haley J., Lockwood, Christina M., Hagemann, Ian S., O’Guin, Stephanie M., Burcea, Lauren C., Sawyer, Christopher S., Oschwald, Dayna M., Stratman, Jennifer L., Sher, Dorie A., Johnson, Mark R., Brown, Justin T., Cliften, Paul F., George, Bijoy, McIntosh, Leslie D., Shrivastava, Savita, Nguyen, TuDung T., Payton, Jacqueline E., Watson, Mark A., Crosby, Seth D., Head, Richard D., Mitra, Robi D., Nagarajan, Rakesh, Kulkarni, Shashikant, Seibert, Karen, Virgin, Herbert W., IV, Milbrandt, Jeffrey, Pfeifer, John D.

Source: In The Journal of Molecular Diagnostics January 2014 16(1):89-105

61. Clinical whole exome/whole transcriptome analysis detects clinically relevant structural alterations in Multiple Myeloma

Authors: Calvo, Maria Nieves, Caruthers, Sean, Tripodi, Joseph, Houldsworth, Jane, Fink, Marc, Newman, Scott, Chen, Rong, Zhang, Wanying, Liu, Liu, Shi, Yong, Jun, Tomi, Onel, Ken, Oh, William, Edelmann, Lisa, Schadt, Eric, Rossi, Michael, Hantash, Feras, Al-Kateb, Hussam

Source: Cancer genetics. 268(S1):20-20

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100176328139.0x000001&indx=1&recIds=ETOCvdc_100176328139.0x000001

857 Clinical-Grade Next Generation Sequencing of 200 Consecutive Patients with Renal Neoplasia.

Authors: McCarthy, Michael, Wojcik, Antonina, Fritcher, Emily Barr, Tekin, Burak, Al-Kateb, Hussam, Dasari, Surendra, Ebare, Kingsley, Reynolds, Jordan, Stanton, Melissa, Raghunathan, Aditya, Whaley, Rumeal, Hernandez, Loren Herrera, Jimenez, Rafael, Costello, Brian, Potretzke, Aaron, Boorjian, Stephen, Sharma, Vidit, Cheville, John, Kipp, Benjamin, Gupta, Sounak

Source: Laboratory Investigation (00236837); 2025 Supplement, Vol. 105 Issue 3, pN.PAG-N.PAG, 1p

Prevalence of Pathogenic Germline Mutations in Solid Tumor Predisposition Genes Detected By Tumor-Normal Whole Exome Sequencing Analysis Among Adults with Hematologic Malignancies

Authors: Al-Kateb, Hussam, Jun, Tomi ^*, Hayes, Jim ^*, Rossi, Michael ^*, Hantash, Feras ^*, Oh, William K., Onel, Kenan

Source: In Blood 15 November 2022 140 Supplement 1:7852-7853

25. Unexpected favorable outcome in a patient with high grade B-cell lymphoma with abnormalities of MYC, BCL6 and BCL2 loci

Authors: Al-Kateb, Hussam, Adams, Thomas, Fuchs, Deborah, Shadoan, Patricia K, Johnstone, Laurel, Lau, Branden M, McGhan, Lee, Anwer, Faiz

Source: Cancer genetics. 224:60-60

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100064052828.0x000001&indx=1&recIds=ETOCvdc_100064052828.0x000001