Advanced Insights into Competitive Endogenous RNAs (ceRNAs) Regulated Pathogenic Mechanisms in Metastatic Triple-Negative Breast Cancer (mTNBC).

Authors: Qattan, Amal^1,2 (AUTHOR) akattan@kfshrc.edu.sa, Al-Tweigeri, Taher³ (AUTHOR) ttwegieri@kfshrc.edu.sa, Suleman, Kausar³ (AUTHOR) ksuleman@kfshrc.edu.sa, Alkhayal, Wafa⁴ (AUTHOR) wkhayal@kfshrc.edu.sa, Tulbah, Asma⁵ (AUTHOR) tulbah@kfshrc.edu.sa

Source: Cancers. Sep2024, Vol. 16 Issue 17, p3057. 16p.

Subject Terms: *EPITHELIAL-mesenchymal transition, *CANCER invasiveness, *MICRORNA, *BREAST tumors, *EPIGENOMICS, *TREATMENT effectiveness, *CELLULAR signal transduction, *CELL motility, *METASTASIS, *GENETIC mutation, *CELL survival, *PHENOTYPES, *GENOTYPES

Peripheral blood eosinophil count is associated with response to chemoimmunotherapy in metastatic triple-negative breast cancer

Authors: Ghebeh, Hazem, Elshenawy, Mahmoud A, AlSayed, Adher D, Al-Tweigeri, Taher

Source: Immunotherapy. 14(4):189-199

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191699253.0x000001&indx=1&recIds=ETOCvdc_100191699253.0x000001

Molecular Subtypes of Breast Cancer in Arab Women: Distribution and Prognostic Insights.

Authors: Elkum, Naser, Aboussekhra, Abdelilah, Aboussekhra, Mouad, Aldalham, Hanin, Alshehri, Lama, Alessy, Saleh, AL-Tweigeri, Taher, Al-Zahrani, Ali Saeed

Source: Journal of Epidemiology & Global Health; 3/10/2025, Vol. 15 Issue 1, p1-9, 9p

Subject Terms: EPIDERMAL growth factor receptors, SAUDI Arabians, PROPORTIONAL hazards models, MEDICAL sciences, SURVIVAL rate

Ribociclib-Induced Pneumonitis: A Case Report

Authors: Algwaiz, Ghada, Badran, Ahmed Ali, Elshenawy, Mahmoud A., Al-Tweigeri, Taher

Source: Breast care. 16(3):307-311

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100121686687.0x000001&indx=1&recIds=ETOCvdc_100121686687.0x000001

Trastuzumab, Pertuzumab, and Docetaxel as the First Line for HER-2-Positive Metastatic Breast Cancer among Arabs

Authors: Suleman, Kausar, Mushtaq, Ali Hassan, Haque, Emaan, Badran, Ahmed Ali, Ajarim, Dahish, Elashwah, Ahmed Mohammed, Gad, Ahmed Mostafa, Abdelsamad, Amgad Shaheen, Omar, Ayman, Khan, Khurshid Ahmed, Al-Tweigeri, Taher, Elshentenawy, Ayman, Alsayed, Adher

Source: Breast care. 16(1):59-65

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100115232637.0x000001&indx=1&recIds=ETOCvdc_100115232637.0x000001

Tocilizumab potentiates cisplatin cytotoxicity and targets cancer stem cells in triple‐negative breast cancer

Authors: Alraouji, Noura N., Al‐Mohanna, Falah H., Ghebeh, Hazem, Arafah, Maria, Almeer, Rafa, Al‐Tweigeri, Taher, Aboussekhra, Abdelilah

Source: Molecular carcinogenesis. 59(9):1041-1051

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100108139995.0x000001&indx=1&recIds=ETOCvdc_100108139995.0x000001

Does the Timing of Surgery after Neoadjuvant Therapy in Breast Cancer Patients Affect the Outcome?

Authors: Suleman, Kausar, Almalik, Osama, Haque, Emaan, Mushtaq, Ali, Badran, Ahmed, Alsayed, Adher, Ajarim, Dahish, Al-Tweigeri, Taher, Jastaniyah, Noha, Elhassan, Tusneem, Alkhayal, Wafa

Source: Oncology. 98(3):168-173

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100099129090.0x000001&indx=1&recIds=ETOCvdc_100099129090.0x000001

Β1 Integrin is essential for fascin‐mediated breast cancer stem cell function and disease progression

Authors: Barnawi, Rayanah, Al‐Khaldi, Samiyah, Colak, Dilek, Tulbah, Asma, Al‐Tweigeri, Taher, Fallatah, Mohannad, Monies, Dorota, Ghebeh, Hazem, Al‐Alwan, Monther

Source: International journal of cancer. 145(3):830-841

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100084080585.0x000001&indx=1&recIds=ETOCvdc_100084080585.0x000001

Long noncoding RNA DLEU2 and ROR1 pathway induces epithelial-to-mesenchymal transition and cancer stem cells in breast cancer.

Authors: Islam, Syed S., Al-Tweigeri, Taher, Al-Harbi, Layla, Ujjahan, Shafat, Al-Mozaini, Maha, Tulbah, Asma, Aboussekhra, Abdelilah

Source: Cell Death Discovery; 1/31/2024, Vol. 10 Issue 1, p1-14, 14p

Clinical and functional significance of tumor/stromal ATR expression in breast cancer patients

Authors: Al-Ansari, Mysoon M., Al-Saif, Maher, Arafah, Maria, Eldali, Abdelmonneim M., Tulbah, Asma, Al-Tweigeri, Taher, Semlali, Abdelhabib, Khabar, Khalid S., Aboussekhra, Abdelilah

Source: Breast cancer research. 22(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100171990236.0x000001&indx=1&recIds=ETOCvdc_100171990236.0x000001

p16INK4A Represses Breast Stromal Fibroblasts Migration/Invasion and Their VEGF-A-dependent Promotion of Angiogenesis through Akt Inhibition

Authors: Al-Ansari, Mysoon M., Hendrayani, Siti-Fauziah, Tulbah, Asma, Al-Tweigeri, Taher, Shehata, Afaf I., Aboussekhra, Abdelilah

Source: In Neoplasia December 2012 14(12):1269-1277

Prevalence of PIK3CA mutations and the SNP rs17849079 in Arab breast cancer patients

Authors: Karakas, Bedri, Colak, Dilek, Kaya, Namik, Ghebeh, Hazem, Al-Qasem, Abeer, Hendrayani, Fawziah, Toulimat, Mohamed, Al-Tweigeri, Taher, Park, Ben Ho, Aboussekhra, Abdelilah

Source: Cancer biology & therapy. 14(10):888-896

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100050659158.0x000001&indx=1&recIds=ETOCvdc_100050659158.0x000001

Metaplastic breast cancer: Disease characteristics and outcome in Arab women.

Authors: Alsayed, Adher, Alshamsan, Bader I, Alshibany, Aisha, Elshenawy, Mahmoud Abdelsatar, Badran, Ahmed ali, Al-Tweigeri, Taher, Ajarim, Dahish Saed, Suleman, Kausar

Source: Journal of clinical oncology. 39(15 suppl):e12534-e12534

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100173176550.0x000001&indx=1&recIds=ETOCvdc_100173176550.0x000001

High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients.

Authors: Al-Tweigeri, Taher, AlRaouji, Noura N., Tulbah, Asma, Arafah, Maria, Aboussekhra, Mouad, Al-Mohanna, Falah, Gad, Ahmed Mostafa, Eldali, Abdelmonneim M., Elhassan, Tusneem A., Aboussekhra, Abdelilah

Source: Breast Cancer Research; 7/11/2022, Vol. 24 Issue 1, p1-15, 15p

The B7-H1 (PD-L1) T Lymphocyte-Inhibitory Molecule Is Expressed in Breast Cancer Patients with Infiltrating Ductal Carcinoma: Correlation with Important High-Risk Prognostic Factors

Authors: Ghebeh, Hazem, Mohammed, Shamayel, Al-Omair, Abeer, Qattant, Amal, Lehe, Cynthia, Al-Qudaihi, Ghofran, Elkum, Naser, Alshabanah, Mohamed, Bin Amer, Suad, Tulbah, Asma, Ajarim, Dahish, Al-Tweigeri, Taher, Dermime, Said

Source: In Neoplasia March 2006 8(3):190-198

High DNMT1 Expression in Stromal Fibroblasts Promotes Angiogenesis and Unfavorable Outcome in Locally Advanced Breast Cancer Patients.

Authors: Al-Kharashi, Layla A., Tulbah, Asma, Arafah, Maria, Eldali, Abdelmonneim M., Al-Tweigeri, Taher, Aboussekhra, Abdelilah

Source: Frontiers in Oncology; 6/2/2022, Vol. 12, p1-12, 12p

Subject Terms: DECITABINE, CANCER patients, FIBROBLASTS, NEOVASCULARIZATION, STROMAL cells, CANCER cells

Association Between Obesity and Clinicopathological Profile of Patients with Newly Diagnosed Non-Metastatic Breast Cancer in Saudi Arabia.

Authors: Alshamsan, Bader, Suleman, Kausar, Agha, Naela, Abdelgawad, Marwa I, Alzahrani, Mashari J, Elhassan, Tusneem, Al-Tweigeri, Taher, Ajarim, Dahish, Alsayed, Adher

Source: International Journal of Women's Health; Mar2022, Vol. 15, p373-384, 12p

Subject Terms: HORMONE receptor positive breast cancer, BREAST cancer, BODY mass index, OBESITY, CLINICAL pathology, ORAL contraceptives

Geographic Terms: SAUDI Arabia

Association Between Neutrophil-Lymphocyte Ratio and Oncotype Dx Recurrence Score in Early-Stage Hormonal Receptor-Positive, HER2-Negative, Node-Negative Breast Cancer.

Authors: Alshamsan, Bader, Alshibany, Aisha, Elshenawy, Mahmoud A, Badran, Ahmed, Elhassan, Tusneem, Ajarim, Dahish, Alsayed, Adher, Suleman, Kausar, Al-Tweigeri, Taher

Source: Cancer Management & Research; Dec2021, Vol. 13, p9411-9420, 10p

Subject Terms: NEUTROPHIL lymphocyte ratio, EPIDERMAL growth factor receptors, TUMOR grading, RECEIVER operating characteristic curves, BREAST cancer, TUMOR classification, LOGISTIC regression analysis

Prognostic significance of the neutrophil to lymphocyte ratio in locally advanced breast cancer.

Authors: Alshamsan, Bader, Elshenawy, Mahmoud A., Aseafan, Mohamed, Fahmy, Nermin, Badran, Ahmed, Elhassan, Tusneem, Alsayed, Adher, Suleman, Kausar, Al-Tweigeri, Taher

Source: Oncology Letters; Sep2024, Vol. 28 Issue 3, pN.PAG-N.PAG, 1p

Subject Terms: METASTATIC breast cancer, RECEIVER operating characteristic curves, NEUTROPHIL lymphocyte ratio, SURVIVAL rate, LOGISTIC regression analysis

Weekly Paclitaxel given concurrently with Durvalumab has a favorable safety profile in triple-negative metastatic breast cancer.

Authors: Ghebeh, Hazem, Al-Sayed, Adher, Eiada, Riham, Cabangon, Leilani, Ajarim, Dahish, Suleman, Kausar, Tulbah, Asma, Al-Tweigeri, Taher

Source: Scientific Reports; 9/27/2021, Vol. 11 Issue 1, p1-9, 9p

Subject Terms: METASTATIC breast cancer, TRIPLE-negative breast cancer, PACLITAXEL, OVERALL survival, SURVIVAL rate, IRON deficiency