Antibody decay, T cell immunity and breakthrough infections following two SARS-CoV-2 vaccine doses in inflammatory bowel disease patients treated with infliximab and vedolizumab

Authors: Simeng Lin, Nicholas A. Kennedy, Aamir Saifuddin, Diana Muñoz Sandoval, Catherine J. Reynolds, Rocio Castro Seoane, Sherine H. Kottoor, Franziska P. Pieper, Kai-Min Lin, David K. Butler, Neil Chanchlani, Rachel Nice, Desmond Chee, Claire Bewshea, Malik Janjua, Timothy J. McDonald, Shaji Sebastian, James L. Alexander, Laura Constable, James C. Lee, Charles D. Murray, Ailsa L. Hart, Peter M. Irving, Gareth-Rhys Jones, Klaartje B. Kok, Christopher A. Lamb, Charlie W. Lees, Daniel M. Altmann, Rosemary J. Boyton, James R. Goodhand, Nick Powell, Tariq Ahmad, CLARITY IBD study

Source: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/ff70757914a74e03bae010a63c866cc8

Burden of disease and adaptation to life in patients with Crohn’s perianal fistula: a qualitative exploration

Authors: Samuel O. Adegbola, Lesley Dibley, Kapil Sahnan, Tiffany Wade, Azmina Verjee, Rachel Sawyer, Sameer Mannick, Damian McCluskey, Nuha Yassin, Robin K. S. Phillips, Philip J. Tozer, Christine Norton, Ailsa L. Hart

Source: Health and Quality of Life Outcomes, Vol 18, Iss 1, Pp 1-13 (2020)

Subject Terms: Crohn’s anal fistula, Patient reported outcomes, Quality of life, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12955-020-01622-7; https://doaj.org/toc/1477-7525

Access URL: https://doaj.org/article/ecc411c2e4214c14b70eba6901fd452c

Bacteroides thetaiotaomicron-derived outer membrane vesicles promote regulatory dendritic cell responses in health but not in inflammatory bowel disease

Authors: Lydia Durant, Régis Stentz, Alistair Noble, Johanne Brooks, Nadezhda Gicheva, Durga Reddi, Matthew J. O’Connor, Lesley Hoyles, Anne L. McCartney, Ripple Man, E. Tobias Pring, Stella Dilke, Philip Hendy, Jonathan P. Segal, Dennis N. F. Lim, Ravi Misra, Ailsa L. Hart, Naila Arebi, Simon R. Carding, Stella C. Knight

Source: Microbiome, Vol 8, Iss 1, Pp 1-16 (2020)

Subject Terms: Dendritic cells, Outer membrane vesicles, Bacteroides thetaiotaomicron, Interleukin-10, Inflammatory bowel disease, Microbial ecology, QR100-130

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40168-020-00868-z; https://doaj.org/toc/2049-2618

Access URL: https://doaj.org/article/a5c3345e76dd43cfb753bcec8206e6d2

International Consensus on Definition of Mild-to-Moderate Ulcerative Colitis Disease Activity in Adult Patients

Authors: Bénédicte Caron, Vipul Jairath, Ferdinando D’Amico, Sameer Al Awadhi, Axel Dignass, Ailsa L. Hart, Taku Kobayashi, Paulo Gustavo Kotze, Fernando Magro, Britta Siegmund, Kristine Paridaens, Silvio Danese, Laurent Peyrin-Biroulet

Source: Medicina, Vol 59, Iss 1, p 183 (2023)

Subject Terms: ulcerative colitis, mild, moderate, definition, activity, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/1648-9144/59/1/183; https://doaj.org/toc/1010-660X; https://doaj.org/toc/1648-9144

Access URL: https://doaj.org/article/7084dc964d414d2a925b15b511cafcce

Gaps in knowledge and future directions for the use of faecal microbiota transplant in the treatment of inflammatory bowel disease

Authors: Mehmet Yalchin, Jonathan P. Segal, Benjamin H. Mullish, Mohammed Nabil Quraishi, Tariq H. Iqbal, Julian R. Marchesi, Ailsa L. Hart

Source: Therapeutic Advances in Gastroenterology, Vol 12 (2019)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/e557e6d5e4ce486099d64e34576e7689

The gut virome: the ‘missing link’ between gut bacteria and host immunity?

Authors: Indrani Mukhopadhya, Jonathan P. Segal, Simon R. Carding, Ailsa L. Hart, Georgina L. Hold

Source: Therapeutic Advances in Gastroenterology, Vol 12 (2019)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/fa792a3d04be488795a249dc4b1e0f3d

The application of omics techniques to understand the role of the gut microbiota in inflammatory bowel disease

Authors: Jonathan P. Segal, Benjamin H. Mullish, Mohammed Nabil Quraishi, Animesh Acharjee, Horace R. T. Williams, Tariq Iqbal, Ailsa L. Hart, Julian R. Marchesi

Source: Therapeutic Advances in Gastroenterology, Vol 12 (2019)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/447431621e9a4a239c52f1537acfbaaa

Volume assessment magnetic resonance imaging technique for monitoring perianal Crohn’s fistulas

Authors: Phillip F. C. Lung, Kapil Sahnan, David Burling, James Burn, Phillip Tozer, Nuha Yassin, Samuel O. Adegbola, Rachel Baldwin-Cleland, Janindra Warusavitarne, Arun Gupta, Omar Faiz, Robin K. S. Phillips, Ailsa L. Hart

Source: Therapeutic Advances in Gastroenterology, Vol 11 (2018)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/e720ecf4924e4d6093ca9a1d8ddbe11c

Innovation in the imaging of perianal fistula: a step towards personalised medicine

Authors: Kapil Sahnan, Samuel O. Adegbola, Philip J. Tozer, Uday Patel, Rajpandian Ilangovan, Janindra Warusavitarne, Omar D. Faiz, Ailsa L. Hart, Robin K. S. Phillips, Phillip F. C. Lung

Source: Therapeutic Advances in Gastroenterology, Vol 11 (2018)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/32113287059149c382d3a1e3c8fc6c05

Chemokine (C-C Motif) Receptor 2 Mediates Dendritic Cell Recruitment to the Human Colon but Is Not Responsible for Differences Observed in Dendritic Cell Subsets, Phenotype, and Function Between the Proximal and Distal ColonSummary

Authors: David Bernardo, Lydia Durant, Elizabeth R. Mann, Elizabeth Bassity, Enrique Montalvillo, Ripple Man, Rakesh Vora, Durga Reddi, Fahri Bayiroglu, Luis Fernández-Salazar, Nick R. English, Simon T.C. Peake, Jon Landy, Gui H. Lee, George Malietzis, Yi Harn Siaw, Aravinth U. Murugananthan, Phil Hendy, Eva Sánchez-Recio, Robin K.S. Phillips, Jose A. Garrote, Paul Scott, Julian Parkhill, Malte Paulsen, Ailsa L. Hart, Hafid O. Al-Hassi, Eduardo Arranz, Alan W. Walker, Simon R. Carding, Stella C. Knight

Source: Cellular and Molecular Gastroenterology and Hepatology, Vol 2, Iss 1, Pp 22-39.e5 (2016)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352345X15001514; https://doaj.org/toc/2352-345X

Access URL: https://doaj.org/article/43a045023eba4751af960d5f5612c1ab

Dysregulated Circulating Dendritic Cell Function in Ulcerative Colitis Is Partially Restored by Probiotic Strain Lactobacillus casei Shirota

Authors: Elizabeth R. Mann, Jialu You, Verena Horneffer-van der Sluis, David Bernardo, Hafid Omar Al-Hassi, Jon Landy, Simon T. Peake, Linda V. Thomas, Cheng T. Tee, Gui Han Lee, Ailsa L. Hart, Parveen Yaqoob, Stella C. Knight

Source: Mediators of Inflammation, Vol 2013 (2013)

Subject Terms: Pathology, RB1-214

File Description: electronic resource

Relation: https://doaj.org/toc/0962-9351; https://doaj.org/toc/1466-1861

Access URL: https://doaj.org/article/bd54172861994b7ebf1f44fceab9a3ab

Vitamin D and gastrointestinal diseases: inflammatory bowel disease and colorectal cancer

Authors: Maitreyi Raman, Andrew N. Milestone, Julian R.F. Walters, Ailsa L. Hart, Subrata Ghosh

Source: Therapeutic Advances in Gastroenterology, Vol 4 (2011)

Subject Terms: Diseases of the digestive system. Gastroenterology, RC799-869

File Description: electronic resource

Relation: https://doaj.org/toc/1756-283X; https://doaj.org/toc/1756-2848

Access URL: https://doaj.org/article/cc855ef46a134816889809039dfc8172

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Consensus definition of a radiologically healed fistula on magnetic resonance imaging in perianal Crohn’s disease: an international Delphi study

Authors: Ailsa L Hart, Phillip Lung, Phil Tozer, Jalpa Devi, Jaap Stoker, David H Ballard, Shivani Joshi, Michelle Doering, Easan Anand, Anna Antoniou, Parakkal Deepak

Source: BMJ Open, Vol 14, Iss 11 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/11/e087919.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/e1b72486ffc5444c885d9c698bcd3164

Determining the optimal route of faecal microbiota transplant in patients with ulcerative colitis: the STOP-Colitis pilot RCT

Authors: Mohammed N Quraishi, Catherine A Moakes, Mehmet Yalchin, Jonathan Segal, Natalie J Ives, Laura Magill, Susan E Manzoor, Konstantinos Gerasimidis, Shrushma Loi, Christel McMullan, Jonathan Mathers, Christopher Quince, Manjinder Kaur, Nicholas J Loman, Naveen Sharma, Peter Hawkey, Victoria McCune, Ben Nichols, Vaios Svolos, Caroline Kerbiriou, Claire McMurray, Andrew Beggs, Richard Hansen, Ailsa L Hart, Daniel R Gaya, Tariq H Iqbal

Source: Efficacy and Mechanism Evaluation, Vol 11, Iss 14 (2024)

Subject Terms: fmt, ulcerative colitis, pilot randomised trial, microbiota, microbiome, metabolomics, evaluation, qualitative calprotectin, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2050-4373

Access URL: https://doaj.org/article/7bef97db59244e34baf54be028890d2c

Defining predictors of responsiveness to advanced therapies in Crohn’s disease and ulcerative colitis: protocol for the IBD-RESPONSE and nested CD-metaRESPONSE prospective, multicentre, observational cohort study in precision medicine

Authors: Peter M Irving, Miles Parkes, Ruth Wood, Ailsa L Hart, Nicholas A Kennedy, Nick Powell, Julian R Marchesi, Tariq Ahmad, Tim Raine, Andrew King, James O Lindsay, Kevin Whelan, Charlie W Lees, Christopher A Lamb, Jack Satsangi, Emma Clark, Shriya Sharma, Xinyue Zhang, Christopher J Stewart, Naomi McGregor, Helen C Hancock, Rebecca H Maier, John C Mansfield, Mary Doona, Michelle Bardgett, Natalie J Prescott, Trevor Liddle, Robert Lees, Hannah Watson, Carl A Anderson, Ally Speight, Ciara Kennedy, Sarah Lawrence, Nicola J Wyatt, Jennifer A Doyle, Rebecca E McIntyre, Luke Jostins-Dean, Victoria Hildreth, James MS Wason, Dean Allerton, Dawn Clewes, Cristina Cotobal Martin, Katherine Frith, Sameena Iqbal, Laura Letchford, Jasmin Ostermayer, Tolulope Osunnuyi, Tara Shrestha, Michelle Strickland, Gregory R Young

Source: BMJ Open, Vol 14, Iss 4 (2024)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/14/4/e073639.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/12bb87e0caee4e31a4d86e9b0e5adbdd

METRIC-EF: magnetic resonance enterography to predict disabling disease in newly diagnosed Crohn’s disease—protocol for a multicentre, non-randomised, single-arm, prospective study

Authors: Ailsa L Hart, Gauraang Bhatnagar, Stuart Bloom, Steve Halligan, Simon Travis, Roser Vega, Andrew Plumb, John Hamlin, Shankar Kumar, Sue Mallett, Caroline S Clarke, Stuart Andrew Taylor, Ilan Jacobs

Source: BMJ Open, Vol 12, Iss 10 (2022)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/12/10/e067265.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/0e01884b2df2444481d8092201c013cd

STOP-Colitis pilot trial protocol: a prospective, open-label, randomised pilot study to assess two possible routes of faecal microbiota transplant delivery in patients with ulcerative colitis

Authors: Ailsa L Hart, Christel McMullan, Jonathan Mathers, Laura Magill, Natalie J Ives, Tariq Iqbal, Mohammed Nabil Quraishi, Naveen Sharma, Jonathan Segal, Richard Hansen, Mehmet Yalchin, Clare Blackwell, Peter Hawkey, Victoria McCune, Daniel Gaya, Shrushma Loi, Konstantinos Gerasimidis, Nicholas James Loman, Christopher Quince, Nicola Crees

Source: BMJ Open, Vol 9, Iss 11 (2019)

Subject Terms: Medicine

File Description: electronic resource

Relation: https://bmjopen.bmj.com/content/9/11/e030659.full; https://doaj.org/toc/2044-6055

Access URL: https://doaj.org/article/f422a02b0b204b77bfb2bb6a58d6e78d

Magnetic resonance enterography compared with ultrasonography in newly diagnosed and relapsing Crohn’s disease patients: the METRIC diagnostic accuracy study

Authors: Stuart A Taylor, Sue Mallett, Gauraang Bhatnagar, Stephen Morris, Laura Quinn, Florian Tomini, Anne Miles, Rachel Baldwin-Cleland, Stuart Bloom, Arun Gupta, Peter John Hamlin, Ailsa L Hart, Antony Higginson, Ilan Jacobs, Sara McCartney, Charles D Murray, Andrew AO Plumb, Richard C Pollok, Manuel Rodriguez-Justo, Zainib Shabir, Andrew Slater, Damian Tolan, Simon Travis, Alastair Windsor, Peter Wylie, Ian Zealley, Steve Halligan

Source: Health Technology Assessment, Vol 23, Iss 42 (2019)

Subject Terms: CROHN DISEASE, INTESTINE, SMALL, COLONIC DISEASES, TECHNOLOGY ASSESSMENT, BIOMEDICAL, MAGNETIC RESONANCE IMAGING, ULTRASONOGRAPHY, PROSPECTIVE STUDIES, SENSITIVITY AND SPECIFICITY, COST–BENEFIT ANALYSIS, OBSERVER VARIATION, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1366-5278; https://doaj.org/toc/2046-4924

Access URL: https://doaj.org/article/3e4d79d7d5e543728e5706900761bdae