Affinity molecular assay for detecting Candida albicans using chitin affinity and RPA-CRISPR/Cas12a

Authors: Shimei Shen, Wen Wang, Yuanyan Ma, Shilei Wang, Shaocheng Zhang, Xuefei Cai, Liang Chen, Jin Zhang, Yalan Li, Xiaoli Wu, Jie Wei, Yanan Zhao, Ailong Huang, Siqiang Niu, Deqiang Wang

Source: Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

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Epigenetic regulation and its therapeutic potential in hepatitis B virus covalently closed circular DNA

Authors: Jihua Ren, Shengtao Cheng, Fang Ren, Huiying Gu, Daiqing Wu, Xinyan Yao, Ming Tan, Ailong Huang, Juan Chen

Source: Genes and Diseases, Vol 12, Iss 1, Pp 101215- (2025)

Subject Terms: cccDNA, Epigenetic regulation, HBV, HBx, Transcription, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304224000126; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/c4e54444db5c4a8cb77e57230a753505

Comprehensive analysis of immune subtype characterization on identification of potential cells and drugs to predict response to immune checkpoint inhibitors for hepatocellular carcinoma

Authors: Guichuan Lai, Biao Xie, Cong Zhang, Xiaoni Zhong, Jielian Deng, Kangjie Li, Hui Liu, Yuan Zhang, Anbin Liu, Yi Liu, Jie Fan, Tianyi Zhou, Wei Wang, Ailong Huang

Source: Genes and Diseases, Vol 12, Iss 3, Pp 101471- (2025)

Subject Terms: Cellular heterogeneity, Drug prediction, Hepatocellular carcinoma, Immune checkpoint inhibitors, Immunosubtyping, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235230422400268X; https://doaj.org/toc/2352-3042

Access URL: https://doaj.org/article/739031ad6cbe48a1b0dd0f60d66eb5a4

The proteasome activator subunit PSME1 promotes HBV replication by inhibiting the degradation of HBV core protein

Authors: Yu Liu, Jiaxin Yang, Yanyan Wang, Qiqi Zeng, Yao Fan, Ailong Huang, Hui Fan

Source: Genes and Diseases, Vol 11, Iss 6, Pp 101142- (2024)

Subject Terms: 26S proteasome, APEX2, HBc, HBV, Host-viral interactions, PSME1, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304223004257; https://doaj.org/toc/2352-3042

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Retraction Note: Long noncoding RNA MIR31HG inhibits hepatocellular carcinoma proliferation and metastasis by sponging microRNA-575 to modulate ST7L expression

Authors: Shaoying Yan, Zhenrong Tang, Ke Chen, Yuyang Liu, Gangfeng Yu, Qiuxu Chen, Hao Dang, Fengjiao Chen, Jiaji Ling, Liying Zhu, Ailong Huang, Hua Tang

Source: Journal of Experimental & Clinical Cancer Research, Vol 44, Iss 1, Pp 1-1 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/ba3fde1abadc42918efe701e8d420db8

Efficacy of rapid antigen self-testing for SARS-CoV-2 screening: Real-world evidence from a prospective cohort study

Authors: Yaoyue Hu, Bin Peng, Jie Fan, Zhu Yang, Jianjiang Xue, Quanxin Long, Jie Xia, Yuan Hu, Xuefei Cai, Li Zhou, Ailong Huang

Source: Genes and Diseases, Vol 11, Iss 5, Pp 101151- (2024)

Subject Terms: Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304223004348; https://doaj.org/toc/2352-3042

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EGR1 suppresses HCC growth and aerobic glycolysis by transcriptionally downregulating PFKL

Authors: Mingang Pan, Muyu Luo, Lele Liu, Yunmeng Chen, Ziyi Cheng, Kai Wang, Luyi Huang, Ni Tang, Jianguo Qiu, Ailong Huang, Jie Xia

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-18 (2024)

Subject Terms: HCC, EGR1, PFKL, Glycolysis, Sorafenib, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/527f86176a7b419c9ec0890af8ed4cbb

Real-world effectiveness of an intranasal spray A8G6 antibody cocktail in the post-exposure prophylaxis of COVID-19

Authors: Xiaosong Li, Pai Peng, Haijun Deng, Qian Yang, Shi Chen, Benhua Li, Miao He, Aishun Jin, Zhu Yang, Ni Tang, Ailong Huang

Source: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-8 (2023)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/91bb3851c2d149838b245de4013ac598

HOXA‐AS2 Epigenetically Inhibits HBV Transcription by Recruiting the MTA1‐HDAC1/2 Deacetylase Complex to cccDNA Minichromosome

Authors: YiPing Qin, JiHua Ren, HaiBo Yu, Xin He, ShengTao Cheng, WeiXian Chen, Zhen Yang, FengMing Sun, ChunDuo Wang, SiYu Yuan, Peng Chen, DaiQing Wu, Fang Ren, AiLong Huang, Juan Chen

Source: Advanced Science, Vol 11, Iss 24, Pp n/a-n/a (2024)

Subject Terms: cccDNA, Hepatitis B virus, HOXA‐AS2, MTA1‐HDAC1/2 deacetylase complex, self‐limiting HBV replication, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/994e96827c194040b4553d71491308ce

Metabolic Enzyme SLC27A5 Regulates PIP4K2A pre‐mRNA Splicing as a Noncanonical Mechanism to Suppress Hepatocellular Carcinoma Metastasis

Authors: Dan Nie, Xin Tang, Haijun Deng, Xiaojun Yang, Junji Tao, Fengli Xu, Yi Liu, Kang Wu, Kai Wang, Zhechuan Mei, Ailong Huang, Ni Tang

Source: Advanced Science, Vol 11, Iss 5, Pp n/a-n/a (2024)

Subject Terms: alternative splicing, HCC, nonmetabolic functions, PIP4K2A‐S, SLC27A5, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/926382a551044c81a0a93bb998c11356

Loss of SLC27A5 Activates Hepatic Stellate Cells and Promotes Liver Fibrosis via Unconjugated Cholic Acid

Authors: Kang Wu, Yi Liu, Jie Xia, Jiale Liu, Kai Wang, Huijun Liang, Fengli Xu, Dina Liu, Dan Nie, Xin Tang, Ailong Huang, Chang Chen, Ni Tang

Source: Advanced Science, Vol 11, Iss 2, Pp n/a-n/a (2024)

Subject Terms: bile acid, early growth response protein 3, hepatic stellate cells, liver fibrosis, solute carrier family 27 member 5, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2198-3844

Access URL: https://doaj.org/article/ba427bc07c0e46f790f26f8641ff1c6b

PLEKHG5 is stabilized by HDAC2-related deacetylation and confers sorafenib resistance in hepatocellular carcinoma

Authors: Yu Sha, Mingang Pan, Yunmeng Chen, Liangjun Qiao, Hengyu Zhou, Dina Liu, Wenlu Zhang, Kai Wang, Luyi Huang, Ni Tang, Jianguo Qiu, Ailong Huang, Jie Xia

Source: Cell Death Discovery, Vol 9, Iss 1, Pp 1-13 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Cytology, QH573-671

File Description: electronic resource

Relation: https://doaj.org/toc/2058-7716

Access URL: https://doaj.org/article/20d87786c12e494cb9553c14e7aa7e5f

Durability of Hepatitis B surface antigen seroclearance in patients experienced nucleoside analogs or interferon monotherapy: A real-world data from Electronic Health Record

Authors: Zongqi Shi, Huizhi Zheng, Miaomiao Han, Jieli Hu, Yuan Hu, Xiaosong Li, Wenyan Zhu, Xinjun He, Haijun Deng, Quanxin Long, Ailong Huang

Source: Genes and Diseases, Vol 10, Iss 3, Pp 1019-1028 (2023)

Subject Terms: anti-HBs, Chronic hepatitis B Infection, Clinical outcomes after HBsAg seroclearance, Durability of HBsAg seroclearance, Interferon monotherapy, Nucleoside analogs monotherapy, Medicine (General), R5-920, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2352304222000563; https://doaj.org/toc/2352-3042

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Deficiency of gluconeogenic enzyme PCK1 promotes metabolic-associated fatty liver disease through PI3K/AKT/PDGF axis activation in male mice

Authors: Qian Ye, Yi Liu, Guiji Zhang, Haijun Deng, Xiaojun Wang, Lin Tuo, Chang Chen, Xuanming Pan, Kang Wu, Jiangao Fan, Qin Pan, Kai Wang, Ailong Huang, Ni Tang

Source: Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/a30c45d28e9344e29e4f12528c65a86c

O-GlcNAcylation of YTHDF2 promotes HBV-related hepatocellular carcinoma progression in an N6-methyladenosine-dependent manner

Authors: Yang Yang, Yu Yan, Jiaxin Yin, Ni Tang, Kai Wang, Luyi Huang, Jie Hu, Zhongqi Feng, Qingzhu Gao, Ailong Huang

Source: Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-16 (2023)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/2e009c9d152d487690e3ee125802b510

Hepatitis B virus promotes its own replication by enhancing RAB5A-mediated dual activation of endosomal and autophagic vesicle pathways

Authors: Zhenyu Zhao, Zhen Wei, Jiaxin Zheng, Zhihong Li, Hecun Zou, Xiang Wen, Fahong Li, Xueyu Wang, Qian Huang, Huaqing Zeng, Hui Fan, Xuefei Cai, Jiming Zhang, Bei Jia, Ailong Huang, Mengji Lu, Yong Lin

Source: Emerging Microbes and Infections, Vol 12, Iss 2 (2023)

Subject Terms: Hepatitis B virus, RAB5A, autophagy, endosome, VPS34, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/81d600794b4c48c38d85bfc31e91d737

Obatoclax inhibits SARS-CoV-2 entry by altered endosomal acidification and impaired cathepsin and furin activity in vitro

Authors: Binli Mao, Vu Thuy Khanh Le-Trilling, Kai Wang, Denise Mennerich, Jie Hu, Zhenyu Zhao, Jiaxin Zheng, Yingying Deng, Benjamin Katschinski, Shilei Xu, Guiji Zhang, Xuefei Cai, Yuan Hu, Jianwei Wang, Mengji Lu, Ailong Huang, Ni Tang, Mirko Trilling, Yong Lin

Source: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 483-497 (2022)

Subject Terms: obatoclax, sars-cov-2, endocytosis, membrane fusion, mcl-1, Infectious and parasitic diseases, RC109-216, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/2222-1751

Access URL: https://doaj.org/article/2cc623b759fd4f6bbe6c4382c628268d

Gluconeogenic enzyme PCK1 supports S-adenosylmethionine biosynthesis and promotes H3K9me3 modification to suppress hepatocellular carcinoma progression

Authors: Dongmei Gou, Rui Liu, Xiaoqun Shan, Haijun Deng, Chang Chen, Jin Xiang, Yi Liu, Qingzhu Gao, Zhi Li, Ailong Huang, Kai Wang, Ni Tang

Source: The Journal of Clinical Investigation, Vol 133, Iss 13 (2023)

Subject Terms: Metabolism, Oncology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1558-8238

Access URL: https://doaj.org/article/c2745cb0faa24ba9867badce3e416096

Immunomolecular assay based on selective virion capture by spike antibody and viral nucleic acid amplification for detecting intact SARS-CoV-2 particles

Authors: Xiaoli Wu, Junye Liu, Hongpeng Zhang, Hua Zhou, Wen Wang, Yuanyan Ma, Shimei Shen, Xuefei Cai, Ailong Huang, Deqiang Wang

Source: Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-12 (2022)

Subject Terms: COVID-19, Complete virions, Spike, Infection risk, Immunomolecular detection, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/d53622d97fbd461faba2350fd75cccbe

A potent neutralizing antibody provides protection against SARS-CoV-2 Omicron and Delta variants via nasal delivery

Authors: Xinghai Zhang, Huajun Zhang, Tingting Li, Shaohong Chen, Feiyang Luo, Junhui Zhou, Peiyi Zheng, Shuyi Song, Yan Wu, Tengchuan Jin, Ni Tang, Aishun Jin, Chengyong Yang, Guofeng Cheng, Rui Gong, Sandra Chiu, Ailong Huang

Source: Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-8 (2022)

Subject Terms: Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2059-3635

Access URL: https://doaj.org/article/ddeeb71f1afd48939b2470dcc6c55279