Targeting NLRC5 in cardiomyocytes protects postinfarction cardiac injury by enhancing autophagy flux through the CAVIN1/CAV1 axis

Authors: Lingfeng Gu, Sibo Wang, Liuhua Zhou, Wenjing Wang, Yulin Bao, Ye He, Tongtong Yang, Jiateng Sun, Qiqi Jiang, Tiankai Shan, Chong Du, Zemu Wang, Hao Wang, Liping Xie, Aihua Gu, Yang Zhao, Yong Ji, Qiming Wang, Liansheng Wang

Source: Communications Biology, Vol 8, Iss 1, Pp 1-17 (2025)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

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Correction: Ibrutinib, a Bruton’s tyrosine kinase inhibitor, exhibits antitumoral activity and induces autophagy in glioblastoma

Authors: Jin Wang, Xiaoyang Liu, Yongzhi Hong, Songtao Wang, Pin Chen, Aihua Gu, Xiaoyuan Guo, Peng Zhao

Source: Journal of Experimental & Clinical Cancer Research, Vol 44, Iss 1, Pp 1-5 (2025)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

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Bisphenol S decreased lifespan and healthspan via insulin/IGF-1-like signaling-against mitochondrial stress in Caenorhabditis elegans

Authors: Wenmiao He, Zhiwei Liu, Hongchao Zhang, Qian Liu, Zhenkun Weng, Dongmei Wang, Wenhui Guo, Jin Xu, Dayong Wang, Zhaoyan Jiang, Aihua Gu

Source: Ecotoxicology and Environmental Safety, Vol 285, Iss , Pp 117136- (2024)

Subject Terms: C. elegans, Bisphenol S, Quercetin, Lifespan, Healthspan, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

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Relation: http://www.sciencedirect.com/science/article/pii/S0147651324012120; https://doaj.org/toc/0147-6513

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siRNA/CS‐PLGA Nanoparticle System Targeting Knockdown Intestinal SOAT2 Reduced Intestinal Lipid Uptake and Alleviated Obesity

Authors: Jingjia Liang, Wentao Shao, Pu Ni, Qian Liu, Weirui Kong, Weiyi Shen, Qihan Wang, Anhua Huang, Guixin Zhang, Yulong Yang, Hongliang Xin, Zhaoyan Jiang, Aihua Gu

Source: Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)

Subject Terms: CD36, intestinal fatty acid absorption, obesity, PLGA‐b‐PEG, Sterol O‐acyltransferase 2, Science

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Relation: https://doaj.org/toc/2198-3844

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Association of air pollution exposure and increased coronary artery disease risk: the modifying effect of genetic susceptibility

Authors: Zuqiang Fu, Yuanyuan Ma, Changjie Yang, Qian Liu, Jingjia Liang, Zhenkun Weng, Wenxiang Li, Shijie Zhou, Xiu Chen, Jin Xu, Cheng Xu, Tao Huang, Yong Zhou, Aihua Gu

Source: Environmental Health, Vol 22, Iss 1, Pp 1-11 (2023)

Subject Terms: Air pollution, Coronary artery disease, Polygenic risk score, Gene‒environment interaction, Industrial medicine. Industrial hygiene, RC963-969, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1476-069X

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Sp1-activated FGFR2 is involved in early-life exposure to nickel-induced craniosynostosis by regulating the ERK1/2 signaling pathway

Authors: Zhenkun Weng, Cheng Xu, Xiu Chen, Qing Yan, Zuqiang Fu, Jian Jiao, Jin Xu, Qian Liu, Dongmei Wang, Jingjia Liang, Wenxiang Li, Aihua Gu

Source: Environment International, Vol 184, Iss , Pp 108477- (2024)

Subject Terms: Nickel, Craniosynostosis, FGFR2, ERK1/2 signaling, DNA methylation, Environmental sciences, GE1-350

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Relation: http://www.sciencedirect.com/science/article/pii/S0160412024000631; https://doaj.org/toc/0160-4120

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Dietary diosgenin transcriptionally down-regulated intestinal NPC1L1 expression to prevent cholesterol gallstone formation in mice

Authors: Weiyi Shen, Wentao Shao, Qihan Wang, Bo Wang, Gang Zhao, Aihua Gu, Zhaoyan Jiang, Hai Hu

Source: Journal of Biomedical Science, Vol 30, Iss 1, Pp 1-14 (2023)

Subject Terms: Gallstone, Diosgenin, Cholesterol, NPC1L1, Microbiome, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/96fc622cd8304c4b809fff014b613a88

Interactions among maternal smoking, breastfeeding, and offspring genetic factors on the risk of adult-onset hypertension

Authors: Jingjia Liang, Zuqiang Fu, Qian Liu, Yuehong Shen, Xin Zhang, Zhenkun Weng, Jin Xu, Wenxiang Li, Cheng Xu, Yong Zhou, Aihua Gu

Source: BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)

Subject Terms: Maternal smoking, Breastfeeding, Polygenic risk score, Adult-onset hypertension, Prospective cohort study, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1741-7015

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Research on the Modeling of Automatic Pricing and Replenishment Strategies for Perishable Goods with Time-Varying Deterioration Rates

Authors: Aihua Gu, Zhongzhen Yan, Xixi Zhang, Yongsheng Xiang

Source: Axioms, Vol 13, Iss 1, p 62 (2024)

Subject Terms: data mining and analysis, support vector machines, neural networks, supermarket sales strategy, cost-plus pricing, Mathematics, QA1-939

File Description: electronic resource

Relation: https://www.mdpi.com/2075-1680/13/1/62; https://doaj.org/toc/2075-1680

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Gut microbiota promotes cholesterol gallstone formation by modulating bile acid composition and biliary cholesterol secretion

Authors: Hai Hu, Wentao Shao, Qian Liu, Ning Liu, Qihan Wang, Jin Xu, Xin Zhang, Zhenkun Weng, Qifan Lu, Long Jiao, Chaobo Chen, Haidong Sun, Zhaoyan Jiang, Xiaoping Zhang, Aihua Gu

Source: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

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Association of air pollutants and osteoporosis risk: The modifying effect of genetic predisposition

Authors: Cheng Xu, Zhenkun Weng, Qian Liu, Jin Xu, Jingjia Liang, Wenxiang Li, Jia Hu, Tao Huang, Yong Zhou, Aihua Gu

Source: Environment International, Vol 170, Iss , Pp 107562- (2022)

Subject Terms: Air pollution, Polygenic risk score, Genetic susceptibility, Osteoporosis, Additive interaction, Environmental sciences, GE1-350

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0160412022004895; https://doaj.org/toc/0160-4120

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An Axin2 mutation and perinatal risk factors contribute to sagittal craniosynostosis: evidence from a Chinese female monochorionic diamniotic twin family

Authors: Jin Xu, Qing Yan, Chengcheng Song, Jingjia Liang, Liang Zhao, Xin Zhang, Zhenkun Weng, Cheng Xu, Qian Liu, Shuqin Xu, Lu Pang, Liye Zhang, Yuan Sun, Gang Wang, Aihua Gu

Source: Hereditas, Vol 158, Iss 1, Pp 1-11 (2021)

Subject Terms: Sagittal craniosynostosis, Axin2, Perinatal risk factors, Mutation, Monochorionic diamniotic twin, Genetics, QH426-470

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Relation: https://doaj.org/toc/1601-5223

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Comparisons of tri-ponderal mass index and body mass index in discriminating hypertension at three separate visits in adolescents: A retrospective cohort study

Authors: Jia Hu, Yi Zhong, WenXin Ge, Huiling Lv, Ziyao Ding, Di Han, Bo Hai, Hui Shen, Jieyun Yin, Aihua Gu, Haibing Yang

Source: Frontiers in Nutrition, Vol 9 (2022)

Subject Terms: adolescents, body mass index, hypertension, pediatric, tri-ponderal mass index, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2022.1028861/full; https://doaj.org/toc/2296-861X

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Prevalence of hypertension and related risk factors among children and adolescents at three separate visits: A large school-based study in China

Authors: Jia Hu, Ziyao Ding, Di Han, Bo Hai, Huiling Lv, Jieyun Yin, Hui Shen, Aihua Gu, Haibing Yang

Source: Frontiers in Pediatrics, Vol 10 (2022)

Subject Terms: adolescents, blood pressure, children, hypertension, risk factors, three visits, Pediatrics, RJ1-570

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Relation: https://www.frontiersin.org/articles/10.3389/fped.2022.976317/full; https://doaj.org/toc/2296-2360

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Hsp90 S-nitrosylation at Cys521, as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis

Authors: Shuang Zhao, Xin Tang, Zian Miao, Yurong Chen, Jiawei Cao, Tianyu Song, Daiting You, Yanqing Zhong, Zhe Lin, Dan Wang, Zhiguang Shi, Xinlong Tang, Dongjin Wang, Shaoliang Chen, Liansheng Wang, Aihua Gu, Feng Chen, Liping Xie, Zhengrong Huang, Hong Wang, Yong Ji

Source: Redox Biology, Vol 52, Iss , Pp 102290- (2022)

Subject Terms: Heat shock protein 90, S-nitrosylation, Atherosclerosis, Oxidative stress, Endothelial dysfunction, Medicine (General), R5-920, Biology (General), QH301-705.5

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Relation: http://www.sciencedirect.com/science/article/pii/S2213231722000623; https://doaj.org/toc/2213-2317

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Sulfonate-Modified Polystyrene Nanoparticle at Precited Environmental Concentrations Induces Transgenerational Toxicity Associated with Increase in Germline Notch Signal of Caenorhabditis elegans

Authors: Wenmiao He, Aihua Gu, Dayong Wang

Source: Toxics, Vol 11, Iss 6, p 511 (2023)

Subject Terms: C. elegans, transgenerational toxicity, nanoplastic, Notch signal, Chemical technology, TP1-1185

File Description: electronic resource

Relation: https://www.mdpi.com/2305-6304/11/6/511; https://doaj.org/toc/2305-6304

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Maternal smoking during pregnancy is risk factor for gallbladder disease in offspring during adulthood: a prospective study from UK Biobank

Authors: Wenxiang Li, Jingjia Liang, Wentao Shao, Cheng Xu, Jin Xu, Zhaoyan Jiang, Aihua Gu

Source: Annals of Hepatology, Vol 26, Iss , Pp 100558- (2021)

Subject Terms: UK Biobank, Gallbladder disease, Gallstone, Maternal smoking, Specialties of internal medicine, RC581-951

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Relation: http://www.sciencedirect.com/science/article/pii/S166526812100257X; https://doaj.org/toc/1665-2681

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Single Cell RNA-Sequencing Reveals a Murine Gallbladder Cell Transcriptome Atlas During the Process of Cholesterol Gallstone Formation

Authors: Jingjia Liang, Wentao Shao, Qian Liu, Qifan Lu, Aihua Gu, Zhaoyan Jiang

Source: Frontiers in Cell and Developmental Biology, Vol 9 (2021)

Subject Terms: cholesterol gallstone, gallbladder, single-cell RNA sequencing, lithogenesis, ursodeoxycholic acid, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2021.714271/full; https://doaj.org/toc/2296-634X

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Birth Weight and Adult Obesity Index in Relation to the Risk of Hypertension: A Prospective Cohort Study in the UK Biobank

Authors: Yi Zhang, Jingjia Liang, Qian Liu, Xikang Fan, Cheng Xu, Aihua Gu, Wei Zhao, Dong Hang

Source: Frontiers in Cardiovascular Medicine, Vol 8 (2021)

Subject Terms: birth weight, adult obesity index, hypertension, blood pressure, epidemiology, prospective study, Diseases of the circulatory (Cardiovascular) system, RC666-701

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Relation: https://www.frontiersin.org/articles/10.3389/fcvm.2021.637437/full; https://doaj.org/toc/2297-055X

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HDL cholesterol: A potential mediator of the association between urinary cadmium concentration and cardiovascular disease risk

Authors: Cheng Xu, Zhenkun Weng, Liye Zhang, Jin Xu, Maginsh Dahal, Til Bahadur Basnet, Aihua Gu

Source: Ecotoxicology and Environmental Safety, Vol 208, Iss , Pp 111433- (2021)

Subject Terms: Cardiovascular disease, Cadmium, NHANES, WQS, Mediation analysis, Environmental pollution, TD172-193.5, Environmental sciences, GE1-350

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Relation: http://www.sciencedirect.com/science/article/pii/S0147651320312707; https://doaj.org/toc/0147-6513

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