High cell throughput, programmable fixation reveals the RNA and protein co-regulation with spatially resolved NFκB pseudo-signaling

Authors: Nicholas Zhang, Mingshuang Wang, Dhruv Nambiar, Samyukta Iyer, Priyam Kadakia, Qianqi Luo, Sicheng Pang, Aaron Qu, Nivik Sanjay Bharadwaj, Peng Qiu, Ahmet F. Coskun

Source: APL Bioengineering, Vol 8, Iss 4, Pp 046108-046108-17 (2024)

Subject Terms: Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2473-2877

Access URL: https://doaj.org/article/7d4d73b9fbdc4f55aae03d6aafef9f61

Single-cell spatial metabolomics with cell-type specific protein profiling for tissue systems biology

Authors: Thomas Hu, Mayar Allam, Shuangyi Cai, Walter Henderson, Brian Yueh, Aybuke Garipcan, Anton V. Ievlev, Maryam Afkarian, Semir Beyaz, Ahmet F. Coskun

Source: Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/005c3c264bfd4983a199d821ea1bd797

Spatial subcellular organelle networks in single cells

Authors: Mythreye Venkatesan, Nicholas Zhang, Benoit Marteau, Yukina Yajima, Nerea Ortiz De Zarate Garcia, Zhou Fang, Thomas Hu, Shuangyi Cai, Adam Ford, Harrison Olszewski, Andrew Borst, Ahmet F. Coskun

Source: Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/9bbd5f5e6dc14ed5a9612c11b696e296

Single-cell RNA-sequencing and subcellular spatial transcriptomics facilitate the translation of liver microphysiological systems for regulatory application

Authors: Dan Li, Zhou Fang, Qiang Shi, Nicholas Zhang, Binsheng Gong, Weida Tong, Ahmet F. Coskun, Joshua Xu

Source: Journal of Pharmaceutical Analysis, Vol 13, Iss 7, Pp 691-693 (2023)

Subject Terms: Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2095177923001259; https://doaj.org/toc/2095-1779

Access URL: https://doaj.org/article/24c6f24a66074ea08ab225136cf50050

Spatially variant immune infiltration scoring in human cancer tissues

Authors: Mayar Allam, Thomas Hu, Jeongjin Lee, Jeffrey Aldrich, Sunil S. Badve, Yesim Gökmen-Polar, Manali Bhave, Suresh S. Ramalingam, Frank Schneider, Ahmet F. Coskun

Source: npj Precision Oncology, Vol 6, Iss 1, Pp 1-21 (2022)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2397-768X

Access URL: https://doaj.org/article/9e5070068683451ebbd1a83b5eb66b7b

Subcellular localization of biomolecules and drug distribution by high-definition ion beam imaging

Authors: Xavier Rovira-Clavé, Sizun Jiang, Yunhao Bai, Bokai Zhu, Graham Barlow, Salil Bhate, Ahmet F. Coskun, Guojun Han, Chin-Min Kimmy Ho, Chuck Hitzman, Shih-Yu Chen, Felice-Alessio Bava, Garry P. Nolan

Source: Nature Communications, Vol 12, Iss 1, Pp 1-18 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/18ad42beb0ae47dfab30d767ad938893

Spatially visualized single-cell pathology of highly multiplexed protein profiles in health and disease

Authors: Mayar Allam, Thomas Hu, Shuangyi Cai, Krishnan Laxminarayanan, Robert B. Hughley, Ahmet F. Coskun

Source: Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2399-3642

Access URL: https://doaj.org/article/58ad3fe1ce344e29a65c37672e679c0a

Multiplexed protein profiling reveals spatial subcellular signaling networks

Authors: Shuangyi Cai, Thomas Hu, Mythreye Venkatesan, Mayar Allam, Frank Schneider, Suresh S. Ramalingam, Shi-Yong Sun, Ahmet F. Coskun

Source: iScience, Vol 25, Iss 9, Pp 104980- (2022)

Subject Terms: Biological sciences, Biotechnology, Biological sciences research methodologies, Biology experimental methods, Science

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2589004222012524; https://doaj.org/toc/2589-0042

Access URL: https://doaj.org/article/2973f78274a64a138c9d983aadb5dd2c

Nanoscopic subcellular imaging enabled by ion beam tomography

Authors: Ahmet F. Coskun, Guojun Han, Shambavi Ganesh, Shih-Yu Chen, Xavier Rovira Clavé, Stefan Harmsen, Sizun Jiang, Christian M. Schürch, Yunhao Bai, Chuck Hitzman, Garry P. Nolan

Source: Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)

Subject Terms: Science

File Description: electronic resource

Relation: https://doaj.org/toc/2041-1723

Access URL: https://doaj.org/article/882ce2bc30f347449f3e0769771cb2d7

Cellular sociology regulates the hierarchical spatial patterning and organization of cells in organisms

Authors: Shambavi Ganesh, Beliz Utebay, Jeremy Heit, Ahmet F. Coskun

Source: Open Biology, Vol 10, Iss 12 (2020)

Subject Terms: quantitative biology, cell-to-cell interactions, sociology of cells, multiplex bioimaging, spatial patterning, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/2046-2441

Access URL: https://doaj.org/article/690f93551b7d48c8ab8cfe402f0a36d8

COVID-19 Diagnostics, Tools, and Prevention

Authors: Mayar Allam, Shuangyi Cai, Shambavi Ganesh, Mythreye Venkatesan, Saurabh Doodhwala, Zexing Song, Thomas Hu, Aditi Kumar, Jeremy Heit, COVID-19 Study Group, Ahmet F. Coskun

Source: Diagnostics, Vol 10, Iss 6, p 409 (2020)

Subject Terms: COVID-19, SARS-CoV-2, rapid testing, immunity, vaccines, 3D printing, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/10/6/409; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/819b10617cbc4d8c8be9d88ffa5dc5e5

Lensless Fluorescent Microscopy on a Chip

Authors: Ahmet F. Coskun, author¹, Ting-Wei Su, author¹, Ikbal Sencan, author¹, Aydogan Ozcan, author¹

Source: Journal of Visualized Experiments. (54)

Availability: http://www.jove.com/video/3181

Giga-pixel lensfree holographic microscopy and tomography using color image sensors.

Authors: Serhan O Isikman, Alon Greenbaum, Wei Luo, Ahmet F Coskun, Aydogan Ozcan

Source: PLoS ONE, Vol 7, Iss 9, p e45044 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3440383?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/98d4d992de854dc3b1570cd8c3ad6431

Lensfree fluorescent on-chip imaging of transgenic Caenorhabditis elegans over an ultra-wide field-of-view.

Authors: Ahmet F Coskun, Ikbal Sencan, Ting-Wei Su, Aydogan Ozcan

Source: PLoS ONE, Vol 6, Iss 1, p e15955 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3017097?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/ab8df71a6e3f4f7eb3619b849456f09f