Design, synthesis, cytotoxicity and 3D-QSAR analysis of new 3,6-disubstituted-1,2,4,5-tetrazine derivatives as potential antitumor agents

Authors: Cañete-Molina, Álvaro, Espinosa-Bustos, Christian, González-Castro, Marcos, Faúndez, Mario, Mella, Jaime, Tapia, Ricardo A., Cabrera, Alan R., Brito, Iván, Aguirre, Adam, Salas, Cristian O.

Source: In Arabian Journal of Chemistry November 2019 12(7):1092-1107

Recombinant Domain of Flagellin Promotes In Vitro a Chemotactic Inflammatory Profile in Human Immune Cells Independently of a Dendritic Cell Phenotype.

Authors: González-Stegmaier, Roxana¹ (AUTHOR) roxana.gonzalez@falp.org, Aguirre, Adam¹ (AUTHOR), Cárcamo, Constanza¹ (AUTHOR), Aguila-Torres, Patricia² (AUTHOR), Villarroel-Espíndola, Franz¹ (AUTHOR) roxana.gonzalez@falp.org

Source: Molecules. Mar2023, Vol. 28 Issue 5, p2394. 13p.

Subject Terms: *FLAGELLIN, *DENDRITIC cells, *MONONUCLEAR leukocytes, *FISH pathogens, *PHENOTYPES, *CHEMOKINE receptors

Design, synthesis, cytotoxicity and 3D-QSAR analysis of new 3, 6-disubstituted-1, 2, 4, 5-tetrazine derivatives as potential antitumor agents

Authors: Cañete-Molina, Álvaro, Espinosa-Bustos, Christian, González-Castro, Marcos, Faúndez, Mario, Mella, Jaime, Tapia, Ricardo A., Cabrera, Alan R., Brito, Iván, Aguirre, Adam, Salas, Cristian O.

Source: Arabian journal of chemistry. 12(7):1092-1107

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100112198666.0x000001&indx=1&recIds=ETOCvdc_100112198666.0x000001

New imidoyl-indazole platinum (II) complexes as potential anticancer agents: Synthesis, evaluation of cytotoxicity, cell death and experimental-theoretical DNA interaction studies

Authors: Cabrera, Alan R., Espinosa-Bustos, Christian, Faúndez, Mario, Meléndez, Jaime, Jaque, Pablo, Daniliuc, Constantin G., Aguirre, Adam, Rojas, Rene S., Salas, Cristian O.

Source: In Journal of Inorganic Biochemistry September 2017 174:90-101

Synthesis of 4(3H)quinazolinimines with selective cytotoxic effect on human acute promyelocytic leukemia cells

Authors: Becerra, Alexandra, Quintero, Celso, Morales, Valeria, Valderrama, Mauricio, Aguirre, Adam, Faúndez, Mario A., Rojas, Rene S.

Source: In Bioorganic & Medicinal Chemistry 15 May 2017 25(10):2681-2688

Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic cells

Authors: Wehinger, Sergio, Ortiz, Rina, Díaz, María Inés, Aguirre, Adam, Valenzuela, Manuel, Llanos, Paola, Mc Master, Christopher, Leyton, Lisette, Quest, Andrew F.G.

Source: In BBA - Molecular Basis of Disease May 2015 1852(5):693-708

Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances pro-inflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability

Authors: Lopez-Lastra Marcelo, Kalergis Alexis M, Ferres Marcela, Pino Karla, Aguirre Adam, Fournet Alexandra, García Stephanie, Marsac Delphine, Veas Francisco

Source: Virology Journal, Vol 8, Iss 1, p 223 (2011)

Subject Terms: Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: http://www.virologyj.com/content/8/1/223; https://doaj.org/toc/1743-422X

Access URL: https://doaj.org/article/8f66d5c020634eabafe2afd406331c13

Tolerogenic Dendritic Cells Derived from Donors with Natural Rubber Latex Allergy Modulate Allergen-Specific T-Cell Responses and IgE Production.

Authors: Escobar, Alejandro¹ jano@med.uchile.cl, Aguirre, Adam², Guzmán, María Antonieta³, González, Rodrigo⁴, Catalán, Diego⁵, Acuña-Castillo, Claudio⁶, Larrondo, Milton⁴, López, Mercedes⁵, Pesce, Barbara⁵, Rolland, Jennifer⁷, O’Hehir, Robyn⁷, Aguillón, Juan Carlos⁵ jaguillo@med.uchile.cl

Source: PLoS ONE. Jan2014, Vol. 9 Issue 1, p1-10. 10p.

Subject Terms: *DENDRITIC cells, *RUBBER, *LATEX allergy, *T cells, *IMMUNOGLOBULIN E, *CELL proliferation, *IMMUNOTHERAPY

Possible Involvement of TLRs and Hemichannels in Stress-Induced CNS Dysfunction via Mastocytes, and Glia Activation.

Authors: Aguirre, Adam^1,2 aaguirred@uc.cl, Maturana, Carola J.^1,2, Harcha, Paloma A.^1,2, Sáez, Juan C.^1,2

Source: Mediators of Inflammation. 2013, Vol. 2013, p1-17. 17p.

Subject Terms: *ASTROCYTES, *TOLL-like receptors, *SCHIZOPHRENIA, *ENZYME activation, *GENE expression, *ETIOLOGY of diseases

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Drawing the Line: Spatial Strategies of Community and Resistance in Post-SB1070 Arizona.

Authors: Boyce, Geoffrey A., Launius, Sarah, Aguirre, Adam O.

Source: ACME: An International Journal for Critical Geographies; 2019, Vol. 18 Issue 1, p188-216, 30p

Subject Terms: EMIGRATION & immigration, GEOGRAPHIC boundaries, ACTIVISM, CITIZENSHIP

People: OLSON, Joel

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FasL-triggered death of Jurkat cells requires caspase 8-induced, ATP-dependent cross-talk between Fas and the purinergic receptor P2X7.

Authors: Aguirre, Adam, Shoji, Kenji F., Sáez, Juan C., Henríquez, Mauricio, Quest, Andrew FG

Source: Journal of Cellular Physiology; Feb2013, Vol. 228 Issue 2, p485-493, 9p, 1 Diagram, 7 Graphs

Subject Terms: FAS proteins, CASPASES, ADENOSINE triphosphate, PURINERGIC receptors, LIGANDS (Biochemistry), CELL death, APYRASE

Infection of human monocyte-derived dendritic cells by ANDES Hantavirus enhances proinflammatory state, the secretion of active MMP-9 and indirectly enhances endothelial permeability.

Authors: Marsac, Delphine, García, Stephanie, Fournet, Alexandra, Aguirre, Adam, Pino, Karla, Ferres, Marcela, Kalergis, Alexis M., Lopez-Lastra, Marcelo, Veas, Francisco

Source: Virology Journal; 2011, Vol. 8 Issue 1, p223-231, 9p, 1 Color Photograph, 3 Graphs

Subject Terms: HANTAVIRUS diseases, RODENTS as carriers of disease, MONOCYTES, DENDRITIC cells, ENDOTHELIUM

Geographic Terms: SOUTHERN States

An anti-human recombinant tumor necrosis factor alpha (TNF$\alpha$) monoclonal antibody recognizes an epitope in feline TNF$\alpha$

Authors: Aguirre, Adam, Escobar, Alejandro, Ferreira, Viviana, Molina, María C., Ferreira, Arturo, Aguillón, Juan C.

Source: Veterinary Research; 2003, Vol. 34 Issue: 2 p177-184, 8p