Application of urinary peptide-biomarkers in trauma patients as a predictive tool for prognostic assessment, treatment and intervention timing

Authors: Gökmen Aktas, Felix Keller, Justyna Siwy, Agnieszka Latosinska, Harald Mischak, Jorge Mayor, Jan Clausen, Michaela Wilhelmi, Vesta Brauckmann, Stephan Sehmisch, Tarek Omar Pacha

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-12 (2025)

Subject Terms: Urine, Biomarker, Trauma, Polytrauma, Intensive care, Critical care, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/fbeff67b5a7e4c83b911f0a5abc39660

Urinary peptides provide information about the risk of mortality across a spectrum of diseases and scenarios

Authors: Felix Keller, Joachim Beige, Justyna Siwy, Alexandre Mebazaa, Dewei An, Harald Mischak, Joost P. Schanstra, Marika Mokou, Paul Perco, Jan A. Staessen, Antonia Vlahou, Agnieszka Latosinska

Source: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-11 (2023)

Subject Terms: Death, Mass spectrometry, Peptidomics, Personalised medicine, Urinary biomarkers, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/a3cf124b0572411f8e6cda3305979cf0

OSTEO18, a novel urinary proteomic signature, associated with osteoporosis in heart transplant recipients

Authors: Yu-Ling Yu, Qi-Fang Huang, De-Wei An, Julia Raad, Dries S. Martens, Agnieszka Latosinska, Katarzyna Stolarz-Skrzypek, Johan Van Cleemput, Ying-Qing Feng, Harald Mischak, Karel Allegaert, Peter Verhamme, Stefan Janssens, Tim S. Nawrot, Jan A. Staessen

Source: Heliyon, Vol 10, Iss 2, Pp e24867- (2024)

Subject Terms: Osteoporosis, Heart transplantation, Bone, Urinary proteomics, Science (General), Q1-390, Social sciences (General), H1-99

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2405844024008983; https://doaj.org/toc/2405-8440

Access URL: https://doaj.org/article/4a45f0c1030a4db9ae5cc1f2dbe08ef3

Small peptide CSF fingerprint of amyotrophic lateral sclerosis.

Authors: Rea Lumi, Susanne Petri, Justyna Siwy, Agnieszka Latosinska, Julia Raad, Petra Zürbig, Thomas Skripuletz, Harald Mischak, Joachim Beige

Source: PLoS ONE, Vol 19, Iss 4, p e0302280 (2024)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0302280&type=printable; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/65c6fef84d5a4de386c7270fee331b33

Integration of Urinary Peptidome and Fecal Microbiome to Explore Patient Clustering in Chronic Kidney Disease

Authors: Emmanouil Mavrogeorgis, Sophie Valkenburg, Justyna Siwy, Agnieszka Latosinska, Griet Glorieux, Harald Mischak, Joachim Jankowski

Source: Proteomes, Vol 12, Iss 2, p 11 (2024)

Subject Terms: chronic kidney disease, CE-MS, CKD, feces, microbiome, peptidome, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2227-7382/12/2/11; https://doaj.org/toc/2227-7382

Access URL: https://doaj.org/article/c17bca75014d42309d06625af0072fc6

The novel proteomic signature for cardiac allograft vasculopathy

Authors: Dongmei Wei, Sander Trenson, Jan M. Van Keer, Jesus Melgarejo, Ella Cutsforth, Lutgarde Thijs, Tianlin He, Agnieszka Latosinska, Agnieszka Ciarka, Thomas Vanassche, Lucas Van Aelst, Stefan Janssens, Johan Van Cleemput, Harald Mischak, Jan A. Staessen, Peter Verhamme, Zhen‐Yu Zhang

Source: ESC Heart Failure, Vol 9, Iss 2, Pp 1216-1227 (2022)

Subject Terms: Heart transplantation, Cardiac allograft vasculopathy, Biomarkers, Proteomics, Diagnosis, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/9675e28feb07487a983a19d9c6beef63

Urine peptidome analysis in cardiorenal syndrome reflects molecular processes

Authors: Eleni Petra, Tianlin He, Vasiliki Lygirou, Agnieszka Latosinska, Harald Mischak, Antonia Vlahou, Joachim Jankowski

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/bd1fd87424a543878fa977fe627fdbdc

Prognosis and Personalized In Silico Prediction of Treatment Efficacy in Cardiovascular and Chronic Kidney Disease: A Proof-of-Concept Study

Authors: Mayra Alejandra Jaimes Campos, Iván Andújar, Felix Keller, Gert Mayer, Peter Rossing, Jan A. Staessen, Christian Delles, Joachim Beige, Griet Glorieux, Andrew L. Clark, William Mullen, Joost P. Schanstra, Antonia Vlahou, Kasper Rossing, Karlheinz Peter, Alberto Ortiz, Archie Campbell, Frederik Persson, Agnieszka Latosinska, Harald Mischak, Justyna Siwy, Joachim Jankowski

Source: Pharmaceuticals, Vol 16, Iss 9, p 1298 (2023)

Subject Terms: cardiovascular events, coronary artery disease, heart failure, chronic kidney disease, personalized medicine, urinary biomarkers, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/16/9/1298; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/e3789a7feddf4e3a80ab26fa30895ea4

The novel urinary proteomic classifier HF1 has similar diagnostic and prognostic utility to BNP in heart failure

Authors: Ross T. Campbell, Adam Jasilek, Harald Mischak, Esther Nkuipou‐Kenfack, Agnieszka Latosinska, Paul I. Welsh, Colette E. Jackson, Jane Cannon, Alex McConnachie, Christian Delles, John J.V. McMurray

Source: ESC Heart Failure, Vol 7, Iss 4, Pp 1595-1604 (2020)

Subject Terms: Heart failure, Biomarkers, Proteomics, Collagen, Diagnosis, Prognosis, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2055-5822

Access URL: https://doaj.org/article/ef46f42dcbe34cdba9bc08a266064c61

Bile and urine peptide marker profiles: access keys to molecular pathways and biological processes in cholangiocarcinoma

Authors: Torsten Voigtländer, Jochen Metzger, Holger Husi, Martha M. Kirstein, Martin Pejchinovski, Agnieszka Latosinska, Maria Frantzi, William Mullen, Thorsten Book, Harald Mischak, Michael P. Manns

Source: Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)

Subject Terms: Cholangiocarcinoma, Biomarkers, Biomolecular pathways, Proteomics, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1423-0127

Access URL: https://doaj.org/article/b437f37bb05142849b693743fd5a71d4

A novel urinary biomarker predicts 1-year mortality after discharge from intensive care

Authors: Esther Nkuipou-Kenfack, Agnieszka Latosinska, Wen-Yi Yang, Marie-Céline Fournier, Alice Blet, Blerim Mujaj, Lutgarde Thijs, Elodie Feliot, Etienne Gayat, Harald Mischak, Jan A. Staessen, Alexandre Mebazaa, Zhen-Yu Zhang, The French and European Outcome Registry in Intensive Care Unit Investigators

Source: Critical Care, Vol 24, Iss 1, Pp 1-11 (2020)

Subject Terms: Biomarker, Intensive care medicine, Heart failure, Mortality, Urinary proteomics, Medical emergencies. Critical care. Intensive care. First aid, RC86-88.9

File Description: electronic resource

Relation: https://doaj.org/toc/1364-8535

Access URL: https://doaj.org/article/75856f679f5c40cd8d8c09326b1f1831

Discovery, validation and sequencing of urinary peptides for diagnosis of liver fibrosis—A multicentre study

Authors: Ayman S. Bannaga, Jochen Metzger, Ioannis Kyrou, Torsten Voigtländer, Thorsten Book, Jesus Melgarejo, Agnieszka Latosinska, Martin Pejchinovski, Jan A. Staessen, Harald Mischak, Michael P. Manns, Ramesh P. Arasaradnam

Source: EBioMedicine, Vol 62, Iss , Pp 103083- (2020)

Subject Terms: Liver fibrosis, Capillary electrophoresis mass spectrometry, Urinary peptide marker, Diagnosis, Medicine, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S235239642030459X; https://doaj.org/toc/2352-3964

Access URL: https://doaj.org/article/eb520815cbc84ccdad6e68dfd109e716

The Implant Proteome—The Right Surgical Glue to Fix Titanium Implants In Situ

Authors: Marcus Jäger, Agnieszka Latosinska, Monika Herten, André Busch, Thomas Grupp, Andrea Sowislok

Source: Journal of Functional Biomaterials, Vol 13, Iss 2, p 44 (2022)

Subject Terms: total hip arthroplasty, protein adsorption, proteomics, osseointegration, titanium, bone regeneration, Biotechnology, TP248.13-248.65, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2079-4983/13/2/44; https://doaj.org/toc/2079-4983

Access URL: https://doaj.org/article/0edf5b83158f452da1d8a36e594db4ab

Plasma proteomic analysis reveals altered protein abundances in cardiovascular disease

Authors: Vasiliki Lygirou, Agnieszka Latosinska, Manousos Makridakis, William Mullen, Christian Delles, Joost P. Schanstra, Jerome Zoidakis, Burkert Pieske, Harald Mischak, Antonia Vlahou

Source: Journal of Translational Medicine, Vol 16, Iss 1, Pp 1-12 (2018)

Subject Terms: Cardiovascular disease, Proteomics, Plasma, LC–MS/MS, Proteomic dataset, Biomarker, Medicine

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12967-018-1476-9; https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/f010b98331f24c4d8a9c983f0363d4e8

Molecular Mapping of Urinary Complement Peptides in Kidney Diseases

Authors: Ralph Wendt, Justyna Siwy, Tianlin He, Agnieszka Latosinska, Thorsten Wiech, Peter F. Zipfel, Aggeliki Tserga, Antonia Vlahou, Harald Rupprecht, Lorenzo Catanese, Harald Mischak, Joachim Beige

Source: Proteomes, Vol 9, Iss 4, p 49 (2021)

Subject Terms: complement, peptide, urine, biomarker, kidney disease, proteomics, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2227-7382/9/4/49; https://doaj.org/toc/2227-7382

Access URL: https://doaj.org/article/7e8ebd244afd4f9091edf50c0554b3e4

Collagen-Derived Peptides in CKD: A Link to Fibrosis

Authors: Emmanouil Mavrogeorgis, Harald Mischak, Agnieszka Latosinska, Antonia Vlahou, Joost P. Schanstra, Justyna Siwy, Vera Jankowski, Joachim Beige, Joachim Jankowski

Source: Toxins, Vol 14, Iss 1, p 10 (2021)

Subject Terms: CE-MS, chronic kidney disease, collagen alpha-1(I) chain, fibrosis, urine, Medicine

File Description: electronic resource

Relation: https://www.mdpi.com/2072-6651/14/1/10; https://doaj.org/toc/2072-6651

Access URL: https://doaj.org/article/7d573b720b3242a88cee678ab27e2ffc

Reproducibility Evaluation of Urinary Peptide Detection Using CE-MS

Authors: Emmanouil Mavrogeorgis, Harald Mischak, Agnieszka Latosinska, Justyna Siwy, Vera Jankowski, Joachim Jankowski

Source: Molecules, Vol 26, Iss 23, p 7260 (2021)

Subject Terms: biomarker, capillary electrophoresis, mass spectrometry, peptides, proteomics, urine, Organic chemistry, QD241-441

File Description: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/23/7260; https://doaj.org/toc/1420-3049

Access URL: https://doaj.org/article/5bb3a4d724fd497e8391598ac1a2b2f2

Molecular Changes in Tissue Proteome during Prostate Cancer Development: Proof-of-Principle Investigation

Authors: Agnieszka Latosinska, Katarina Davalieva, Manousos Makridakis, William Mullen, Joost P. Schanstra, Antonia Vlahou, Harald Mischak, Maria Frantzi

Source: Diagnostics, Vol 10, Iss 9, p 655 (2020)

Subject Terms: drug target, personalized medicine, prostate cancer, proteomics, tissue, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/10/9/655; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/5dc27cdb97e2457ebde7aeb3816ff61c

Omics Derived Biomarkers and Novel Drug Targets for Improved Intervention in Advanced Prostate Cancer

Authors: Maria Frantzi, Marie C. Hupe, Axel S. Merseburger, Joost P. Schanstra, Harald Mischak, Agnieszka Latosinska

Source: Diagnostics, Vol 10, Iss 9, p 658 (2020)

Subject Terms: biomarkers, drug targets, omics, prostate cancer, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/10/9/658; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/38b42fa88b1d4b7e9e3b7a9692d992b5

Promise and Implementation of Proteomic Prostate Cancer Biomarkers

Authors: Agnieszka Latosinska, Maria Frantzi, Axel S. Merseburger, Harald Mischak

Source: Diagnostics, Vol 8, Iss 3, p 57 (2018)

Subject Terms: active surveillance, biomarkers, diagnosis, Prostate Cancer, proteomics, Medicine (General), R5-920

File Description: electronic resource

Relation: http://www.mdpi.com/2075-4418/8/3/57; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/27d7e632ea1a4ee7a3862682c7273426