Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions

Authors: Zhao, Yu, Coelho, Camila, Hughes, Amanda L., Lazar-Stefanita, Luciana, Yang, Sandy, Brooks, Aaron N., Walker, Roy S.K., Zhang, Weimin, Lauer, Stephanie, Hernandez, Cindy, Cai, Jitong, Mitchell, Leslie A., Agmon, Neta, Shen, Yue, Sall, Joseph, Fanfani, Viola, Jalan, Anavi, Rivera, Jordan, Liang, Feng-Xia, Bader, Joel S., Stracquadanio, Giovanni, Steinmetz, Lars M., Cai, Yizhi, Boeke, Jef D.

Source: In Cell 22 November 2023 186(24):5220-5236

Synthetic chromosome fusion: Effects on mitotic and meiotic genome structure and function

Authors: Adoff, Greg, Ahn, Ju Young, Annadanam, Anvesh, Annadanam, Surekha, Berger, Henri, Chen, Yi, Chickering, Michael, D’Avino, Andrew, Fishman, Oren, Im, Jay, Kim, Sangmin, Kim, Sunghan, Lim, Hong Seo, Meyer, Lauren, Moyer, Allison, Murphy, Natalie A., Natov, Peter, Radley, Arthur, Scheifele, Lisa, Tripathy, Arushi, Vergara Greeno, Rebeca, Wang, Tony, Wilkerson, Nick, Zeller, Karen, Zheng, Tony, Zhou, Vivian, Luo, Jingchuan, Vale-Silva, Luis A., Raghavan, Adhithi R., Mercy, Guillaume, Heldrich, Jonna, Sun, Xiaoji, Li, Mingyu Kenneth, Zhang, Weimin, Agmon, Neta, Yang, Kun, Cai, Jitong, Stracquadanio, Giovanni, Thierry, Agnès, Zhao, Yu, Coelho, Camila, McCulloch, Laura H., Lauer, Stephanie, Kaback, David B., Bader, Joel S., Mitchell, Leslie A., Mozziconacci, Julien, Koszul, Romain, Hochwagen, Andreas, Boeke, Jef D.

Source: In Cell Genomics 8 November 2023 3(11)

Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae

Authors: Agmon, Neta, Tang, Zuojian, Yang, Kun, Sutter, Ben, Ikushima, Shigehito, Cai, Yizhi, Caravelli, Katrina, Martin, James A., Sun, Xiaoji, Choi, Woo Jin, Zhang, Allen, Stracquadanio, Giovanni, Hao, Haiping, Tu, Benjamin P., Fenyo, David, Bader, Joel S., Boeke, Jef D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2017 Feb . 114(8), E1470-E1479.

Access URL: https://www.jstor.org/stable/26479338

Intrinsic biocontainment : Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes

Authors: Cai, Yizhi, Agmon, Neta, Choi, Woo Jin, Ubide, Alba, Stracquadanio, Giovanni, Caravelli, Katrina, Hao, Haiping, Bader, Joel S., Boeke, Jef D.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2015 Feb 01. 112(6), 1803-1808.

Access URL: https://www.jstor.org/stable/26461511

Total Synthesis of a Functional Designer Eukaryotic Chromosome

Authors: Annaluru, Narayana, Muller, Héloïse, Mitchell, Leslie A., Ramalingam, Sivaprakash, Stracquadanio, Giovanni, Richardson, Sarah M., Dymond, Jessica S., Kuang, Zheng, Scheifele, Lisa Z., Cooper, Eric M., Cai, Yizhi, Zeller, Karen, Agmon, Neta, Han, Jeffrey S., Hadjithomas, Michalis, Tullman, Jennifer, Caravelli, Katrina, Cirelli, Kimberly, Guo, Zheyuan, London, Viktoriya, Yeluru, Apurva, Murugan, Sindurathy, Kandavelou, Karthikeyan, Agier, Nicolas, Fischer, Gilles, Yang, Kun, Martin, Andrew, Bilgel, Murat, Bohutski, Pavlo, Boulier, Kristin M., Capaldo, Brian J., Chang, Joy, Charoen, Kristie, Choi, Woo Jin, Deng, Peter, DiCarlo, James E., Doong, Judy, Dunn, Jessilyn, Feinberg, Jason I., Fernandez, Christopher, Floria, Charlotte E., Gladowski, David, Hadidi, Pasha, Ishizuka, Isabel, Jabbari, Javaneh, Lau, Calvin Y. L., Lee, Pablo A., Li, Sean, Lin, Denise, Linder, Matthias E., Ling, Jonathan, Liu, Jaime, Liu, Jonathan, London, Mariya, Ma, Henry, Mao, Jessica, McDade, Jessica E., McMillan, Alexandra, Moore, Aaron M., Oh, Won Chan, Ouyang, Yu, Patel, Ruchi, Paul, Marina, Paulsen, Laura C., Qiu, Judy, Rhee, Alex, Rubashkin, Matthew G., Soh, Ina Y., Sotuyo, Nathaniel E., Srinivas, Venkatesh, Suarez, Allison, Wong, Andy, Wong, Remus, Xie, Wei Rose, Xu, Yijie, Yu, Allen T., Koszul, Romain, Bader, Joel S., Boeke, Jef D., Chandrasegaran, Srinivasan

Source: Science, 2014 Apr 01. 344(6179), 55-58.

Access URL: http://www.jstor.org/stable/24743570

Extrachromosomal circles of satellite repeats and 5S ribosomal DNA in human cells

Authors: Cohen Sarit, Agmon Neta, Sobol Olga, Segal Daniel

Source: Mobile DNA, Vol 1, Iss 1, p 11 (2010)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://www.mobilednajournal.com/content/1/1/11; https://doaj.org/toc/1759-8753

Access URL: https://doaj.org/article/8132085608a9441ebb4b79ed73bb1ec6

Effect of nuclear architecture on the efficiency of double-strand break repair.

Authors: Agmon, Neta¹, Liefshitz, Batia¹, Zimmer, Christophe², Fabre, Emmanuelle³, Kupiec, Martin¹

Source: Nature Cell Biology. Jun2013, Vol. 15 Issue 6, p694-699. 6p. 1 Chart, 4 Graphs.

Subject Terms: *DOUBLE-stranded RNA, *GENOMICS, *GENETIC recombination, *CROSSING over (Genetics), *NUCLEAR membranes

Engineered dual selection for directed evolution of SpCas9 PAM specificity.

Authors: Goldberg, Gregory W., Spencer, Jeffrey M., Giganti, David O., Camellato, Brendan R., Agmon, Neta, Ichikawa, David M., Boeke, Jef D., Noyes, Marcus B.

Source: Nature Communications; 1/13/2021, Vol. 12 Issue 1, p1-16, 16p

Subject Terms: PROTEIN engineering, STREPTOCOCCUS pyogenes

Proteasome Nuclear Activity Affects Chromosome Stability by Controlling the Turnover of Mms22, a Protein Important for DNA Repair.

Authors: Ben-Aroya, Shay¹, Agmon, Neta², Yuen, Karen¹, Kwok, Teresa¹, McManus, Kirk¹, Kupiec, Martin², Hieter, Philip¹ hieter@msl.ubc.ca

Source: PLoS Genetics. Feb2010, Vol. 6 Issue 2, p1-14. 14p. 1 Chart, 5 Graphs.

Subject Terms: *DNA repair, *PROTEOLYTIC enzymes, *CHROMOSOMES, *GENOTYPE-environment interaction, *YEAST, *PROTEINS, *PHENOTYPES, *GENETICS

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Phylogenetic debugging of a complete human biosynthetic pathway transplanted into yeast.

Authors: Agmon, Neta, Temple, Jasmine, Tang, Zuojian, Schraink, Tobias, Baron, Maayan, Chen, Jun, Mita, Paolo, Martin, James A, Tu, Benjamin P, Yanai, Itai, Fenyö, David, Boeke, Jef D

Source: Nucleic Acids Research; 1/10/2020, Vol. 48 Issue 1, p486-499, 14p

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Low escape-rate genome safeguards with minimal molecular perturbation of Saccharomyces cerevisiae.

Authors: Zuojian Tang, Martin, James A., Xiaoji Sun, Fenyo, David, Agmon, Neta, Boeke, Jef D., Shigehito Ikushima, Kun Yang, Caravelli, Katrina, Woo Jin Choi, Allen Zhang, Haiping Hao, Bader, Joel S., Yizhi Cai, Stracquadanio, Giovanni, Sutter, Ben, Tu, Benjamin P.

Source: Proceedings of the National Academy of Sciences of the United States of America; 2/21/2017, Vol. 114 Issue 8, pE1470-E1479, 10p

Subject Terms: GENE mapping, HISTONE deacetylase, YEAST, POLLUTANTS, SYNTROPHISM

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Intrinsic biocontainment: Multiplex genome safeguards combine transcriptional and recombinational control of essential yeast genes.

Authors: Yizhi Cai, Agmon, Neta, Woo Jin Choi, Ubide, Alba, Stracquadanio, Giovanni, Caravelli, Katrina, Haiping Hao, Bader, Joel S., Boeke, Jef D.

Source: Proceedings of the National Academy of Sciences of the United States of America; 2/10/2015, Vol. 112 Issue 6, p1803-1808, 6p

Subject Terms: PATHOGENIC microorganisms, HISTONES, YEAST genetic engineering, SACCHAROMYCES, CHEMICAL derivatives

Evidence for rolling circle replication of tandem genes in Drosophila.

Authors: Cohen, Sarit, Agmon, Neta, Yacobi, Keren, Mislovati, Margarita, Segal, Daniel

Source: Nucleic Acids Research; Aug2005, Vol. 33 Issue 14, p4519-4526, 8p

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