Monoclonal antibody therapy protects nonhuman primates against mucosal exposure to Lassa virus

Authors: Cross, Robert W., Fenton, Karla A., Woolsey, Courtney, Prasad, Abhishek N., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Dobias, Natalie S., Fears, Alyssa C., Heinrich, Megan L., Geisbert, Joan B., Garry, Robert F., Branco, Luis M., Geisbert, Thomas W.

Source: In Cell Reports Medicine 20 February 2024 5(2)

A recombinant VSV-vectored vaccine rapidly protects nonhuman primates against lethal Nipah virus disease

Authors: Foster, Stephanie L., Woolsey, Courtney, Borisevich, Viktoriya, Agans, Krystle N., Prasad, Abhishek N., Deer, Daniel J., Geisbert, Joan B., Dobias, Natalie S., Fenton, Karla A., Cross, Robert W., Geisbert, Thomas W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2022 Mar . 119(12), 1-12.

Access URL: https://www.jstor.org/stable/27151091

Natural history of Sudan ebolavirus infection in rhesus and cynomolgus macaques

Authors: Woolsey, Courtney, Fears, Alyssa C., Borisevich, Viktoriya, Agans, Krystle N., Dobias, Natalie S., Prasad, Abhishek N., Deer, Daniel J., Geisbert, Joan B., Fenton, Karla A., Geisbert, Thomas W., Cross, Robert W.

Source: Emerging microbes & infections. 11(1):1635-1646

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100194681420.0x000001&indx=1&recIds=ETOCvdc_100194681420.0x000001

A recombinant VSV-vectored vaccine rapidly protects nonhuman primates against heterologous lethal Lassa fever

Authors: Cross, Robert W., Woolsey, Courtney, Prasad, Abhishek N., Borisevich, Viktoriya, Agans, Krystle N., Deer, Daniel J., Geisbert, Joan B., Dobias, Natalie S., Fenton, Karla A., Geisbert, Thomas W.

Source: In Cell Reports 19 July 2022 40(3)

Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses

Authors: Milligan, Jacob C., Davis, Carl W., Yu, Xiaoying, Ilinykh, Philipp A., Huang, Kai, Halfmann, Peter J., Cross, Robert W., Borisevich, Viktoriya, Agans, Krystle N., Geisbert, Joan B., Chennareddy, Chakravarthy, Goff, Arthur J., Piper, Ashley E., Hui, Sean, Shaffer, Kelly C.L., Buck, Tierra, Heinrich, Megan L., Branco, Luis M., Crozier, Ian, Holbrook, Michael R., Kuhn, Jens H., Kawaoka, Yoshihiro, Glass, Pamela J., Bukreyev, Alexander, Geisbert, Thomas W., Worwa, Gabriella, Ahmed, Rafi, Saphire, Erica Ollmann

Source: In Cell 17 March 2022 185(6):995-1007

Therapy for Argentine hemorrhagic fever in nonhuman primates with a humanized monoclonal antibody

Authors: Zeitlin, Larry, Cross, Robert W., Geisbert, Joan B., Borisevich, Viktoriya, Agans, Krystle N., Prasad, Abhishek N., Enterlein, Sven, Aman, M. Javad, Bornholdt, Zachary A., Brennan, Miles B., Campbell, Lioudmila, Kim, Do, Mlakar, Neil, Moyer, Crystal L., Pauly, Michael H., Shestowsky, William, Whaley, Kevin J., Fenton, Karla A., Geisbert, Thomas W.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2021 Mar . 118(11), 1-8.

Access URL: https://www.jstor.org/stable/27027616

Pan-ebolavirus protective therapy by two multifunctional human antibodies

Authors: Gilchuk, Pavlo, Murin, Charles D., Cross, Robert W., Ilinykh, Philipp A., Huang, Kai, Kuzmina, Natalia, Borisevich, Viktoriya, Agans, Krystle N., Geisbert, Joan B., Zost, Seth J., Nargi, Rachel S., Sutton, Rachel E., Suryadevara, Naveenchandra, Bombardi, Robin G., Carnahan, Robert H., Bukreyev, Alexander, Geisbert, Thomas W., Ward, Andrew B., Crowe, James E., Jr.

Source: In Cell 28 October 2021 184(22):5593-5607

Use of convalescent serum reduces severity of COVID-19 in nonhuman primates

Authors: Cross, Robert W., Prasad, Abhishek N., Borisevich, Viktoriya, Woolsey, Courtney, Agans, Krystle N., Deer, Daniel J., Dobias, Natalie S., Geisbert, Joan B., Fenton, Karla A., Geisbert, Thomas W.

Source: In Cell Reports 9 March 2021 34(10)

Monoclonal antibody therapy demonstrates increased virulence of a lineage VII strain of Lassa virus in nonhuman primates.

Authors: Woolsey, Courtney, Cross, Robert W., Prasad, Abhishek N., Agans, Krystle N., Borisevich, Viktoriya, Deer, Daniel J., Dobias, Natalie S., Fears, Alyssa C., Harrison, Mack B., Heinrich, Megan L., Fenton, Karla A., Garry, Robert F., Branco, Luis M., Geisbert, Thomas W.

Source: Emerging Microbes & Infections; Dec2024, Vol. 13 Issue 1, p1-14, 14p

Potent Henipavirus Neutralization by Antibodies Recognizing Diverse Sites on Hendra and Nipah Virus Receptor Binding Protein

Authors: Dong, Jinhui, Cross, Robert W., Doyle, Michael P., Kose, Nurgun, Mousa, Jarrod J., Annand, Edward J., Borisevich, Viktoriya, Agans, Krystle N., Sutton, Rachel, Nargi, Rachel, Majedi, Mahsa, Fenton, Karla A., Reichard, Walter, Bombardi, Robin G., Geisbert, Thomas W., Crowe, James E., Jr.

Source: In Cell 10 December 2020 183(6):1536-1550

A VP35 Mutant Ebola Virus Lacks Virulence but Can Elicit Protective Immunity to Wild-Type Virus Challenge

Authors: Woolsey, Courtney, Menicucci, Andrea R., Cross, Robert W., Luthra, Priya, Agans, Krystle N., Borisevich, Viktoriya, Geisbert, Joan B., Mire, Chad E., Fenton, Karla A., Jankeel, Allen, Anand, Sneha, Ebihara, Hideki, Geisbert, Thomas W., Messaoudi, Ilhem, Basler, Christopher F.

Source: In Cell Reports 17 September 2019 28(12):3032-3046

A Two-Antibody Pan-Ebolavirus Cocktail Confers Broad Therapeutic Protection in Ferrets and Nonhuman Primates

Authors: Bornholdt, Zachary A., Herbert, Andrew S., Mire, Chad E., He, Shihua, Cross, Robert W., Wec, Anna Z., Abelson, Dafna M., Geisbert, Joan B., James, Rebekah M., Rahim, Md Niaz, Zhu, Wenjun, Borisevich, Viktoriya, Banadyga, Logan, Gunn, Bronwyn M., Agans, Krystle N., Wirchnianski, Ariel S., Goodwin, Eileen, Tierney, Kevin, Shestowsky, William S., Bohorov, Ognian, Bohorova, Natasha, Velasco, Jesus, Ailor, Eric, Kim, Do, Pauly, Michael H., Whaley, Kevin J., Alter, Galit, Walker, Laura M., Chandran, Kartik, Zeitlin, Larry, Qiu, Xiangguo, Geisbert, Thomas W., Dye, John M.

Source: In Cell Host & Microbe 9 January 2019 25(1):49-58

Marburg and Ravn Viruses Fail to Cause Disease in the Domestic Ferret ( Mustela putorius furo )

Authors: Cross, Robert W., Mire, Chad E., Agans, Krystle N., Borisevich, Viktoriya, Fenton, Karla A., Geisbert, Thomas W.

Source: The Journal of Infectious Diseases, 2018 Dec . 218, S448-S452.

Access URL: https://www.jstor.org/stable/26576212

Efficacy of Human Monoclonal Antibody Monotherapy Against Bundibugyo Virus Infection in Nonhuman Primates

Authors: Gilchuk, Pavlo, Mire, Chad E., Geisbert, Joan B., Agans, Krystle N., Deer, Daniel J., Cross, Robert W., Slaughter, James C., Flyak, Andrew I., Mani, Jeremy, Pauly, Michael H., Velasco, Jesus, Whaley, Kevin J., Zeitlin, Larry, Geisbert, Thomas W., Crowe, James E.

Source: The Journal of Infectious Diseases, 2018 Dec . 218, S565-S573.

Access URL: https://www.jstor.org/stable/26576227

Postexposure Efficacy of Recombinant Vesicular Stomatitis Virus Vectors Against High and Low Doses of Marburg Virus Variant Angola in Nonhuman Primates

Authors: Woolsey, Courtney, Geisbert, Joan B., Matassov, Demetrius, Agans, Krystle N., Borisevich, Viktoriya, Cross, Robert W., Deer, Daniel J., Fenton, Karla A., Eldridge, John H., Mire, Chad E., Geisbert, Thomas W.

Source: The Journal of Infectious Diseases, 2018 Dec . 218, S582-S587.

Access URL: https://www.jstor.org/stable/26576229

Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates.

Authors: Zeitlin, Larry, Cross, Robert W., Woolsey, Courtney, West, Brandyn R., Borisevich, Viktoriya, Agans, Krystle N., Prasad, Abhishek N., Deer, Daniel J., Stuart, Lauren, McCavitt-Malvido, Maria, Kim, Do H., Pettitt, James, Crowe Jr., James E., Whaley, Kevin J., Veesler, David, Dimitrov, Antony, Abelson, Dafna M., Geisbert, Thomas W., Broder, Christopher C.

Source: Science Translational Medicine; 4/3/2024, Vol. 16 Issue 741, p1-10, 10p

Subject Terms: NIPAH virus, HENDRA virus, CERCOPITHECUS aethiops, AUJESZKY'S disease virus, PRIMATES, VACCINE approval, Q fever

Geographic Terms: BANGLADESH, SOUTHEAST Asia

Assessment of the potential for host-targeted iminosugars UV-4 and UV-5 activity against filovirus infections in vitro and in vivo

Authors: Warfield, Kelly L., Warren, Travis K., Qiu, Xiangguo, Wells, Jay, Mire, Chad E., Geisbert, Joan B., Stuthman, Kelly S., Garza, Nicole L., Van Tongeren, Sean A., Shurtleff, Amy C., Agans, Krystle N., Wong, Gary, Callahan, Michael V., Geisbert, Thomas W., Klose, Brennan, Ramstedt, Urban, Treston, Anthony M.

Source: In Antiviral Research February 2017 138:22-31

Oral and Conjunctival Exposure of Nonhuman Primates to Low Doses of Ebola Makona Virus

Authors: Mire, Chad E., Geisbert, Joan B., Agans, Krystle N., Deer, Daniel J., Fenton, Karla A., Geisbert, Thomas W.

Source: The Journal of Infectious Diseases, 2016 Oct . 214, S263-S267.

Access URL: http://www.jstor.org/stable/44007287

Molecular Diagnostic Field Test for Point-of-Care Detection of Ebola Virus Directly From Blood

Authors: Benzine, Jason W., Brown, Kerry M., Agans, Krystle N., Godiska, Ronald, Mire, Chad E., Gowda, Krishne, Converse, Brandon, Geisbert, Thomas W., Mead, David A., Chander, Yogesh

Source: The Journal of Infectious Diseases, 2016 Oct . 214, S234-S242.

Access URL: http://www.jstor.org/stable/44007283

Passive Immunotherapy: Assessment of Convalescent Serum Against Ebola Virus Makona Infection in Nonhuman Primates

Authors: Mire, Chad E., Geisbert, Joan B., Agans, Krystle N., Thi, Emily P., Lee, Amy C. H., Fenton, Karla A., Geisbert, Thomas W.

Source: The Journal of Infectious Diseases, 2016 Oct . 214, S367-S374.

Access URL: http://www.jstor.org/stable/44007302