Untargeted metabolomics reveals the impact of Liraglutide treatment on metabolome profiling and metabolic pathways in type-2 diabetes mellitus

Authors: Hicham Benabdelkamel, Rajaa Sebaa, Reem H. AlMalki, Afshan Masood, Assim A. Alfadda, Anas M. Abdel Rahman

Source: Saudi Pharmaceutical Journal, Vol 32, Iss 11, Pp 102172- (2024)

Subject Terms: T2DM, GLP-1 analog, Liraglutide, Metabolomics, Metabolome, Pentose and glucuronate interconversion, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1319016424002226; https://doaj.org/toc/1319-0164

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Plasma-based proteomic profiling identifies the distinct regulation of proteins in hyperplasia and endometrial cancer

Authors: Khalid Akkour, Ibrahim O Alanazi, Assim A Alfadda, Afshan Masood, Hani Alhalal, Salini Scaria Joy, Ali Bassi, Eman Alshehri, Moudi A Alwehaibi, Maria Arafah, Hicham Benabdelkamel

Source: BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)

Subject Terms: Endometrial cancer, Hyperplasia, Plasma, Proteomics, 2D-DIGE, MALDI-TOF, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/7df3a60227bc4a879b10588202372338

Label-free quantitative proteomic profiling reveals differential plasma protein expression in patients with obesity after treatment with liraglutide

Authors: Afshan Masood, Hicham Benabdelkamel, Salini Scaria Joy, Abdulaziz Alhossan, Bashayr Alsuwayni, Ghalia Abdeen, Madhawi Aldhwayan, Nora A. Alfadda, Alexander Dimitri Miras, Assim A. Alfadda

Source: Frontiers in Molecular Biosciences, Vol 11 (2024)

Subject Terms: obesity, liraglutide, GLP1 receptor agonist, proteomics, label-free quantification, multimerin-2, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2024.1458675/full; https://doaj.org/toc/2296-889X

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Plasma Proteomic Signature of Endometrial Cancer in Patients with Diabetes

Authors: Muhammad Mujammami, Mohamed Rafiullah, Khalid Akkour, Assim A. Alfadda, Afshan Masood, Salini Scaria Joy, Hani Alhalal, Maria Arafah, Eman Alshehri, Ibrahim O. Alanazi, Hicham Benabdelkamel

Source: ACS Omega, Vol 9, Iss 4, Pp 4721-4732 (2024)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/988ee10d1ff841babe74cbcac13cf611

Multiple Reaction Monitoring–Mass Spectrometric Immunoassay Analysis of Parathyroid Hormone Fragments with Vitamin D Deficiency in Patients with Diabetes Mellitus

Authors: Hicham Benabdelkamel, Refat M. Nimer, Afshan Masood, Maha Al Mogren, Anas M. Abdel Rahman, Assim A. Alfadda

Source: Proteomes, Vol 12, Iss 4, p 30 (2024)

Subject Terms: diabetes, vitamin D deficiency, mass spectrometric immunoassay (MSIA), multiple reaction monitoring, parathyroid hormone, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2227-7382/12/4/30; https://doaj.org/toc/2227-7382

Access URL: https://doaj.org/article/399b489d69e74bbdb5e562ebde5bd8fc

Label-Free Quantitative Proteomics Analysis of Nasal Lavage Fluid in Chronic Rhinosinusitis with Nasal Polyposis

Authors: Musallam Kashoob, Afshan Masood, Assim A. Alfadda, Salini Scaria Joy, Wed Alluhaim, Shahid Nawaz, Mashal Abaalkhail, Omar Alotaibi, Saad Alsaleh, Hicham Benabdelkamel

Source: Biology, Vol 13, Iss 11, p 887 (2024)

Subject Terms: chronic rhinosinusitis, sinusitis, nasal polyposis, label-free quantification, LC-MS/MS, biomarkers, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2079-7737/13/11/887; https://doaj.org/toc/2079-7737

Access URL: https://doaj.org/article/3bdc4c6e40d24e65aca06342e546907e

Metabolomic profile of patients on levothyroxine treatment for hypothyroidism

Authors: Hicham Benabdelkamel, Malak A Jaber, Lina A Dahabiyeh, Afshan Masood, Reem H Almalki, Mohthash Musambil, Anas M Abdel Rahman, Assim A Alfadda

Source: European Thyroid Journal, Vol 12, Iss 4, Pp 1-10 (2023)

Subject Terms: thyroid hormone, hypothyroidism, lc-ms based metabolomics, levothyroxine, lipid disturbance, anabolic effect, bile acid, metabolomics biomarker, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://etj.bioscientifica.com/view/journals/etj/12/4/ETJ-23-0062.xml; https://doaj.org/toc/2235-0802

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Metabolomic Effects of Liraglutide Therapy on the Plasma Metabolomic Profile of Patients with Obesity

Authors: Assim A. Alfadda, Anas M. Abdel Rahman, Hicham Benabdelkamel, Reem AlMalki, Bashayr Alsuwayni, Abdulaziz Alhossan, Madhawi M. Aldhwayan, Ghalia N. Abdeen, Alexander Dimitri Miras, Afshan Masood

Source: Metabolites, Vol 14, Iss 9, p 500 (2024)

Subject Terms: obesity, liraglutide, metabolomics, mass spectrometry, arachidonic acid, biomarkers, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/14/9/500; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/c2d47837a1a74d21a7a3848433def29a

Urinary Proteome Differences in Patients with Type 2 Diabetes Pre and Post Liraglutide Treatment

Authors: Mohamed Rafiullah, Hicham Benabdelkamel, Afshan Masood, Aishah A. Ekhzaimy, Mohthash Musambil, Salini Scaria Joy, Assim A. Alfadda

Source: Current Issues in Molecular Biology, Vol 45, Iss 2, Pp 1407-1421 (2023)

Subject Terms: GLP-1 receptors agonist, liraglutide, metallothionein-2, proteomics, type 2 diabetes mellitus, zinc-alpha-2-glycoprotein, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/1467-3045/45/2/92; https://doaj.org/toc/1467-3037; https://doaj.org/toc/1467-3045

Access URL: https://doaj.org/article/f3eb8dcc9c35436cab0a607e6c7ed7e3

Metabolomic Profiling of Blood Plasma in Females with Hyperplasia and Endometrial Cancer

Authors: Hicham Benabdelkamel, Malak A. Jaber, Khalid Akkour, Reem H. AlMalki, Assim A. Alfadda, Afshan Masood, Salini Scaria Joy, Hani Alhalal, Moudi A. Alwehaibi, Maria Arafah, Eman Alshehri, Anas M. Abdel Rahman

Source: Metabolites, Vol 14, Iss 2, p 109 (2024)

Subject Terms: endometrial cancer, hyperplasia (HP), metabolomics, LC-HRMS, energy metabolism, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.mdpi.com/2218-1989/14/2/109; https://doaj.org/toc/2218-1989

Access URL: https://doaj.org/article/ba9f897cf95f42ed861177b2b1c80bf6

Isolation and molecular characterization of multidrug-resistant Salmonella enterica serovars

Authors: Mysoon M. Al-Ansari, Moneerah M. Aljubali, Ali M. Somily, Ahmad M. Albarrag, Afshan Masood

Source: Journal of Infection and Public Health, Vol 14, Iss 12, Pp 1767-1776 (2021)

Subject Terms: Salmonella, Chicken, PCR characterization, Antibiotic resistance profiling, Infectious and parasitic diseases, RC109-216, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1876034121003324; https://doaj.org/toc/1876-0341

Access URL: https://doaj.org/article/33970694f55b41f7a4df43b84d6d0d95

The metabolomics approach revealed a distinctive metabolomics pattern associated with hyperthyroidism treatment

Authors: Malak A. Jaber, Hicham Benabdelkamel, Lina A. Dahabiyeh, Afshan Masood, Reem H. AlMalki, Mohthash Musambil, Assim A. Alfadda, Anas M. Abdel Rahman

Source: Frontiers in Endocrinology, Vol 13 (2022)

Subject Terms: hyperthyroidism, carbimazole, metabolomics, acylcarnitines, tryptophan metabolism, redox hemostasis, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2022.1050201/full; https://doaj.org/toc/1664-2392

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Proteomic Profiling Identifies Distinct Regulation of Proteins in Obese Diabetic Patients Treated with Metformin

Authors: Awad Alshahrani, Ahmad Aljada, Afshan Masood, Muhammad Mujammami, Assim A. Alfadda, Mohthash Musambil, Ibrahim O. Alanazi, Mohammed Al Dubayee, Anas M. Abdel Rahman, Hicham Benabdelkamel

Source: Pharmaceuticals, Vol 16, Iss 10, p 1345 (2023)

Subject Terms: metformin, proteomics, obesity, type 2 diabetes mellitus, mass spectrometry, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/16/10/1345; https://doaj.org/toc/1424-8247

Access URL: https://doaj.org/article/10f1ca8ffe2a4a2d8d6ccbcf2b96eff1

Proteomic profiling of thyroid tissue in patients with obesity and benign diffuse goiter

Authors: Hicham Benabdelkamel, Mohamed Rafiullah, Afshan Masood, Abdulaziz Alsaif, Mohthash Musambil, Assim A. Alfadda

Source: Frontiers in Endocrinology, Vol 13 (2022)

Subject Terms: thyroid tissue, goiter, proteomics, obese, 2D-DIGE, MALDI-TOF, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2022.923465/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/dafb3a5a709e421abb383084d48736b3

Identification of Protein Changes in the Urine of Hypothyroid Patients Treated with Thyroxine Using Proteomics Approach

Authors: Afshan Masood, Hicham Benabdelkamel, Anwar A. Jammah, Aishah A. Ekhzaimy, Assim A. Alfadda

Source: ACS Omega, Vol 6, Iss 3, Pp 2367-2378 (2021)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/cc69451c8c9b4b16939f961becb0a0e7

Antimicrobial Mechanism and Identification of the Proteins Mediated by Extracts from Asphaltum punjabianum and Myrtus communis

Authors: Kawther Aabed, Afrah E. Mohammed, Hicham Benabdelkamel, Afshan Masood, Assim A. Alfadda, Ibrahim O. Alanazi, Eman A. Alnehmi

Source: ACS Omega, Vol 5, Iss 48, Pp 31019-31035 (2020)

Subject Terms: Chemistry, QD1-999

File Description: electronic resource

Relation: https://doaj.org/toc/2470-1343

Access URL: https://doaj.org/article/97b8b6502c4a42f8a9066480fa1ed65b

Genomic, Proteomic, and Phenotypic Spectrum of Novel O-Sialoglycoprotein Endopeptidase Variant in Four Affected Individuals With Galloway-Mowat Syndrome

Authors: Malak Ali Alghamdi, Hicham Benabdelkamel, Afshan Masood, Narjes Saheb Sharif-Askari, Mahmood Y. Hachim, Hamad Alsheikh, Muddathir H. Hamad, Mustafa A. Salih, Fahad A. Bashiri, Khalid Alhasan, Tarek Kashour, Pilar Guatibonza Moreno, Sabine Schröder, Vasiliki Karageorgou, Aida M. Bertoli-Avella, Hisham Alkhalidi, Dima Z. Jamjoom, Ibrahim A. Alorainy, Assim A. Alfadda, Rabih Halwani

Source: Frontiers in Genetics, Vol 13 (2022)

Subject Terms: Galloway-Mowat syndrome, steroid-resistant nephrotic syndrome, GAMOS, proteomic, KEOPS complex, Genetics, QH426-470

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fgene.2022.806190/full; https://doaj.org/toc/1664-8021

Access URL: https://doaj.org/article/8db6644c11c4473ea480bba4e547fa50

Proteomics Profiling to Distinguish DOCK8 Deficiency From Atopic Dermatitis

Authors: Minnie Jacob, Afshan Masood, Zakiya Shinwari, Mai Abdel Jabbar, Hamoud Al-Mousa, Rand Arnaout, Bandar AlSaud, Majed Dasouki, Ayodele A. Alaiya, Anas M. Abdel Rahman

Source: Frontiers in Allergy, Vol 2 (2021)

Subject Terms: atopic dermatitis, dedicator of cytokinesis (DOCK8), hyper IgE syndrome (HIES), label-free proteomics, biomarker, multiple reaction monitoring, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/falgy.2021.774902/full; https://doaj.org/toc/2673-6101

Access URL: https://doaj.org/article/d1f6d8850f3e45c4a80647f65242f9cb

Rare occurrence of central diabetes insipidus with dermatomyositis in a young male

Authors: Aishah Ekhzaimy, Afshan Masood, Seham Alzahrani, Waleed Al-Ghamdi, Daad Alotaibi, Muhammad Mujammami

Source: Endocrinology, Diabetes & Metabolism Case Reports, Vol 1, Iss 1, Pp 1-5 (2020)

Subject Terms: Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://edm.bioscientifica.com/view/journals/edm/2020/1/EDM19-0070.xml; https://doaj.org/toc/2052-0573

Access URL: https://doaj.org/article/581a62b3b0254d7cb9a66c9257769c75

Tissue-Based Proteomic Profiling in Patients with Hyperplasia and Endometrial Cancer

Authors: Khalid Akkour, Ibrahim O. Alanazi, Assim A. Alfadda, Hani Alhalal, Afshan Masood, Mohthash Musambil, Anas M. Abdel Rahman, Moudi A. Alwehaibi, Maria Arafah, Ali Bassi, Hicham Benabdelkamel

Source: Cells, Vol 11, Iss 13, p 2119 (2022)

Subject Terms: uterus, endometrial cancer, tissue, proteomics, hyperplasia, 2D-DIGE, Cytology, QH573-671

File Description: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/13/2119; https://doaj.org/toc/2073-4409

Access URL: https://doaj.org/article/b0c8459ce4c34c09a72b00b7e779cfba