Reprogramming tumor-associated macrophages with lipid nanosystems reduces PDAC tumor burden and liver metastasis

Authors: Adrián Palencia-Campos, Laura Ruiz-Cañas, Marcelina Abal-Sanisidro, Juan Carlos López-Gil, Sandra Batres-Ramos, Sofia Mendes Saraiva, Balbino Yagüe, Diego Navarro, Sonia Alcalá, Juan A. Rubiolo, Nadège Bidan, Laura Sánchez, Simona Mura, Patrick C. Hermann, María de la Fuente, Bruno Sainz

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-26 (2024)

Subject Terms: Pancreatic ductal adenocarcinoma, Tumor-associated macrophages, Tumor microenvironment, Lipid nanoemulsions, Galunisertib, Liver metastasis, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/1b8793c91b624a6a801204a956631ce0

Targeting cancer stem cell OXPHOS with tailored ruthenium complexes as a new anti-cancer strategy

Authors: Sonia Alcalá, Lara Villarino, Laura Ruiz-Cañas, José R. Couceiro, Miguel Martínez-Calvo, Adrián Palencia-Campos, Diego Navarro, Pablo Cabezas-Sainz, Iker Rodriguez-Arabaolaza, Alfonso Cordero-Barreal, Lucia Trilla-Fuertes, Juan A. Rubiolo, Sandra Batres-Ramos, Mireia Vallespinos, Cristina González-Páramos, Jéssica Rodríguez, Angelo Gámez-Pozo, Juan Ángel Fresno Vara, Sara Fra Fernández, Amparo Benito Berlinches, Nicolás Moreno-Mata, Ana María Torres Redondo, Alfredo Carrato, Patrick C. Hermann, Laura Sánchez, Susana Torrente, Miguel Ángel Fernández-Moreno, José L. Mascareñas, Bruno Sainz

Source: Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-27 (2024)

Subject Terms: Pancreatic ductal adenocarcinoma, Cancer stem cells, Ruthenium complexes, Mitochondrial DNA, Anti-cancer agents, Oxidative phosphorylation, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1756-9966

Access URL: https://doaj.org/article/a0e8a35f5983431287f4bb493ff1d8e0

EVC-EVC2 complex stability and ciliary targeting are regulated by modification with ubiquitin and SUMO

Authors: Pablo Barbeito, Raquel Martin-Morales, Adrian Palencia-Campos, Juan Cerrolaza, Celia Rivas-Santos, Leticia Gallego-Colastra, Jose Antonio Caparros-Martin, Carolina Martin-Bravo, Ana Martin-Hurtado, Laura Sánchez-Bellver, Gemma Marfany, Victor L. Ruiz-Perez, Francesc R. Garcia-Gonzalo

Source: Frontiers in Cell and Developmental Biology, Vol 11 (2023)

Subject Terms: Ellis van Creveld syndrome, Weyers acrofacial dysostosis, ciliopathy, cilia, Hedgehog signaling, ubiquitin, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fcell.2023.1190258/full; https://doaj.org/toc/2296-634X

Access URL: https://doaj.org/article/a86e27311a0c49f7aeba15c269909a16