Tuning DO:DM Ratios Modulates MHC Class II Immunopeptidomes

Authors: Olsson, Niclas, Jiang, Wei, Adler, Lital N., Mellins, Elizabeth D., Elias, Joshua E.

Source: In Molecular & Cellular Proteomics March 2022 21(3)

Regulation of the BCR signalosome by the class II peptide editor, H2-M, affects the development and repertoire of innate-like B cells

Authors: Ghosh, Debopam, Pham, Tho D., Nanaware, Padma P., Sengupta, Deepanwita, Adler, Lital N., Li, Caiyun G., He, Xiao, O'Mara, Mary E., Kantor, Aaron B., Nguyen, Khoa D., Yang, Yang, Eisenlohr, Laurence C., Jensen, Peter E., Herzenberg, Leonore A., Stern, Lawrence J., Boyd, Scott D., Ghosn, Eliver E.B., Mellins, Elizabeth D.

Source: In Cell Reports 25 January 2022 38(4)

The mitochondrial carrier Citrin plays a role in regulating cellular energy during carcinogenesis

Authors: Rabinovich, Shiran, Silberman, Alon, Adler, Lital, Agron, Shani, Levin-Zaidman, Smadar, Bahat, Amir, Porat, Ziv, Ben-Zeev, Efrat, Geva, Inbal, Itkin, Maxim, Malitsky, Sergey, Buchaklian, Adam, Helbling, Daniel, Dimmock, David, Erez, Ayelet

Source: Oncogene. 39(1):164-175

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100193644758.0x000001&indx=1&recIds=ETOCvdc_100193644758.0x000001

Targeting purine synthesis in ASS1-expressing tumors enhances the response to immune checkpoint inhibitors

Authors: Keshet, Rom, Lee, Joo Sang, Adler, Lital, Iraqi, Muhammed, Ariav, Yarden, Lim, Lisha Qiu Jin, Lerner, Shaul, Rabinovich, Shiran, Oren, Roni, Katzir, Rotem, Weiss Tishler, Hila, Stettner, Noa, Goldman, Omer, Landesman, Hadas, Galai, Sivan, Kuperman, Yael, Kuznetsov, Yuri, Brandis, Alexander, Mehlman, Tevi, Malitsky, Sergey, Itkin, Maxim, Koehler, S. Eleonore, Zhao, Yongmei, Talsania, Keyur, Shen, Tsai-wei, Peled, Nir, Ulitsky, Igor, Porgador, Angel, Ruppin, Eytan, Erez, Ayelet

Source: Nature cancer. 1(9):894-908

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100172462850.0x000001&indx=1&recIds=ETOCvdc_100172462850.0x000001

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

Authors: Lee, Joo Sang, Adler, Lital, Karathia, Hiren, Carmel, Narin, Rabinovich, Shiran, Auslander, Noam, Keshet, Rom, Stettner, Noa, Silberman, Alon, Agemy, Lilach, Helbling, Daniel, Eilam, Raya, Sun, Qin, Brandis, Alexander, Malitsky, Sergey, Itkin, Maxim, Weiss, Hila, Pinto, Sivan, Kalaora, Shelly, Levy, Ronen, Barnea, Eilon, Admon, Arie, Dimmock, David, Stern-Ginossar, Noam, Scherz, Avigdor, Nagamani, Sandesh C.S., Unda, Miguel, Wilson, David M., III, Elhasid, Ronit, Carracedo, Arkaitz, Samuels, Yardena, Hannenhalli, Sridhar, Ruppin, Eytan, Erez, Ayelet

Source: In Cell 6 September 2018 174(6):1559-1570

In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls

Authors: Jiang, Wei, Birtley, James, Hung, Shu-Chen, Wang, Weiqi, Chiou, Shin-Heng, Macaubas, Claudia, Kornum, Birgitte, Tian, Lu, Huang, Huang, Adler, Lital, Weaver, Grant, Lu, Liying, Ilstad-Minnihan, Alexandra, Somasundaram, Sriram, Ayyangar, Sashi, Davis, Mark, Stern, Lawrence, Mellins, Elizabeth

Source: Nature communications. 10(1):1-17

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100191014238.0x000001&indx=1&recIds=ETOCvdc_100191014238.0x000001

The invertebrate Caenorhabditis elegans biosynthesizes ascorbate

Authors: Patananan, Alexander N., Budenholzer, Lauren M., Pedraza, Maria E., Torres, Eric R., Adler, Lital N., Clarke, Steven G.

Source: In Archives of Biochemistry and Biophysics 1 March 2015 569:32-44

Lung dendritic-cell metabolism underlies susceptibility to viral infection in diabetes.

Authors: Nobs, Samuel Philip, Kolodziejczyk, Aleksandra A., Adler, Lital, Horesh, Nir, Botscharnikow, Christine, Herzog, Ella, Mohapatra, Gayatree, Hejndorf, Sophia, Hodgetts, Ryan-James, Spivak, Igor, Schorr, Lena, Fluhr, Leviel, Kviatcovsky, Denise, Zacharia, Anish, Njuki, Suzanne, Barasch, Dinorah, Stettner, Noa, Dori-Bachash, Mally, Harmelin, Alon, Brandis, Alexander

Source: Nature; Dec2023, Vol. 624 Issue 7992, p645-652, 8p

Author Correction: In vivo clonal expansion and phenotypes of hypocretin-specific CD4+ T cells in narcolepsy patients and controls

Authors: Jiang, Wei, Birtley, James R., Hung, Shu-Chen, Wang, Weiqi, Chiou, Shin-Heng, Macaubas, Claudia, Kornum, Birgitte, Tian, Lu, Huang, Huang, Adler, Lital, Weaver, Grant, Lu, Liying, Ilstad-Minnihan, Alexandra, Somasundaram, Sriram, Ayyangar, Sashi, Davis, Mark M., Stern, Lawrence J., Mellins, Elizabeth D.

Source: Nature communications. 11(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131058487.0x000001&indx=1&recIds=ETOCvdc_100131058487.0x000001

Systems and Trans-System Level Analysis Identifies Conserved Iron Deficiency Responses in the Plant Lineage

Authors: Urzica, Eugen I., Casero, David, Yamasaki, Hiroaki, Hsieh, Scott I., Adler, Lital N., Karpowicz, Steven J., Blaby-Haas, Crysten E., Clarke, Steven G., Loo, Joseph A., Pellegrini, Matteo, Merchant, Sabeeha S.

Source: The Plant Cell, 2012 Oct 01. 24(10), 3921-3948.

Access URL: https://www.jstor.org/stable/23327032

Impact of Oxidative Stress on Ascorbate Biosynthesis in Chlamydomonas via Regulation of the VTC2 Gene Encoding a GDP-l-galactose Phosphorylase

Authors: Urzica, Eugen I., Adler, Lital N., Page, M. Dudley, Linster, Carole L., Arbing, Mark A., Casero, David, Pellegrini, Matteo, Merchant, Sabeeha S. ^**, Clarke, Steven G. ^**

Source: In Journal of Biological Chemistry 20 April 2012 287(17):14234-14245

A Novel GDP-d-glucose Phosphorylase Involved in Quality Control of the Nucleoside Diphosphate Sugar Pool in Caenorhabditis elegans and Mammals

Authors: Adler, Lital N., Gomez, Tara A., Clarke, Steven G., Linster, Carole L.

Source: In Journal of Biological Chemistry 17 June 2011 286(24):21511-21523

Synergy between B cell receptor/antigen uptake and MHCII peptide editing relies on HLA-DO tuning

Authors: Jiang, Wei, Adler, Lital N., Macmillan, Henriette, Mellins, Elizabeth D.

Source: Scientific reports. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100131427820.0x000001&indx=1&recIds=ETOCvdc_100131427820.0x000001

A Second GDP-l-galactose Phosphorylase in Arabidopsis en Route to Vitamin C: COVALENT INTERMEDIATE AND SUBSTRATE REQUIREMENTS FOR THE CONSERVED REACTION

Authors: Linster, Carole L., Adler, Lital N., Webb, Kristofor, Christensen, Kathryn C., Brenner, Charles, Clarke, Steven G.

Source: In Journal of Biological Chemistry 4 July 2008 283(27):18483-18492

Arabidopsis VTC2 Encodes a GDP-l-Galactose Phosphorylase, the Last Unknown Enzyme in the Smirnoff-Wheeler Pathway to Ascorbic Acid in Plants

Authors: Linster, Carole L., Gomez, Tara A., Christensen, Kathryn C., Adler, Lital N., Young, Brian D., Brenner, Charles, Clarke, Steven G.

Source: In Journal of Biological Chemistry 29 June 2007 282(26):18879-18885

Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis.

Authors: Rabinovich, Shiran¹, Adler, Lital¹, Yizhak, Keren², Sarver, Alona¹, Silberman, Alon¹, Agron, Shani¹, Stettner, Noa¹, Sun, Qin³, Brandis, Alexander⁴, Helbling, Daniel⁵, Korman, Stanley⁶, Itzkovitz, Shalev⁷, Dimmock, David⁵, Ulitsky, Igor¹, Nagamani, Sandesh C. S., Ruppin, Eytan, Erez, Ayelet¹

Source: Nature. 11/19/2015, Vol. 527 Issue 7578, p379-383. 5p. 2 Charts, 8 Graphs.

Subject Terms: *ARGININOSUCCINATE synthetase, *PYRIMIDINE synthesis, *ASPARTATES, *TUMORS, *OSTEOSARCOMA, *CANCER cells, *METABOLIC models, *HETEROCYCLIC compounds synthesis, *CHARTS, diagrams, etc., *PHYSIOLOGY

ASL expression in ALDH1A1⁺ neurons in the substantia nigra metabolically contributes to neurodegenerative phenotype.

Authors: Lerner, Shaul, Eilam, Raya, Adler, Lital, Baruteau, Julien, Kreiser, Topaz, Tsoory, Michael, Brandis, Alexander, Mehlman, Tevie, Ryten, Mina, Botia, Juan A., Ruiz, Sonia Garcia, Garcia, Alejandro Cisterna, Dionisi-Vici, Carlo, Ranucci, Giusy, Spada, Marco, Mazkereth, Ram, McCarter, Robert, Izem, Rima, Balmat, Thomas J., Richesson, Rachel

Source: Human Genetics; Oct2021, Vol. 140 Issue 10, p1471-1485, 15p

Subject Terms: SUBSTANTIA nigra, PHENOTYPES, NEURONS, LABORATORY mice, TYROSINE hydroxylase, DOPAMINERGIC neurons

Author Correction: BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation

Authors: Raffel, Simon, Falcone, Mattia, Kneisel, Niclas, Hansson, Jenny, Wang, Wei, Lutz, Christoph, Bullinger, Lars, Poschet, Gernot, Nonnenmacher, Yannic, Barnert, Andrea, Bahr, Carsten, Zeisberger, Petra, Przybylla, Adriana, Sohn, Markus, Tönjes, Martje, Erez, Ayelet, Adler, Lital, Jensen, Patrizia, Scholl, Claudia, Fröhling, Stefan, Cocciardi, Sibylle, Wuchter, Patrick, Thiede, Christian, Flörcken, Anne, Westermann, Jörg, Ehninger, Gerhard, Lichter, Peter, Hiller, Karsten, Hell, Rüdiger, Herrmann, Carl, Ho, Anthony, Krijgsveld, Jeroen, Radlwimmer, Bernhard, Trumpp, Andreas

Source: Nature. 560(7718):E28-E28

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100175109718.0x000001&indx=1&recIds=ETOCvdc_100175109718.0x000001

This result is not displayed to guests.
Login for full access.

This result is not displayed to guests.
Login for full access.