Retinoic acid-induced alterations enhance eATP-mediated anti-cancer effects in glioma cells: Implications for P2X7 receptor variants as key players

Authors: Szymczak, Bartosz ^a, Pegoraro, Anna ^b, De Marchi, Elena ^b, Grignolo, Marianna ^b, Maciejewski, Bartosz ^c, Czarnecka, Joanna ^a, Adinolfi, Elena ^b, Roszek, Katarzyna ^{a, ⁎}

Source: In BBA - Molecular Basis of Disease March 2025 1871(3)

Administration of P2X7 Receptor Blockers in Oncological Experimental Models

Authors: De Marchi, Elena, Pegoraro, Anna, Adinolfi, Elena

Source: Methods in molecular biology. 2510:303-314

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN629710071&indx=1&recIds=ETOCRN629710071

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

Authors: Tattersall, Luke, Shah, Karan M., Lath, Darren L., Singh, Archana, Down, Jennifer M., De Marchi, Elena, Williamson, Alex, Di Virgilio, Francesco, Heymann, Dominique, Adinolfi, Elena, Fraser, William D., Green, Darrell, Lawson, Michelle A., Gartland, Alison

Source: In Journal of Bone Oncology December 2021 31

The P2X7 Receptor in Oncogenesis and Metastatic Dissemination: New Insights on Vesicular Release and Adenosinergic Crosstalk.

Authors: Adinolfi, Elena¹ (AUTHOR) elena.adinolfi@unife.it, De Marchi, Elena¹ (AUTHOR) marianna.grignolo@unife.it, Grignolo, Marianna¹ (AUTHOR) anna.pegoraro@unife.it, Szymczak, Bartosz² (AUTHOR) b_szymczak@doktorant.umk.pl, Pegoraro, Anna¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Sep2023, Vol. 24 Issue 18, p13906. 15p.

Subject Terms: *CARCINOGENESIS, *METASTASIS, *EXTRACELLULAR vesicles, *STROMAL cells, *EXOSOMES

Role of the P2X7 receptor in tumor-associated inflammation

Authors: Adinolfi, Elena, De Marchi, Elena, Orioli, Elisa, Pegoraro, Anna, Di Virgilio, Francesco

Source: In Current Opinion in Pharmacology August 2019 47:59-64

Detection of Extracellular ATP in the Tumor Microenvironment, Using the pmeLUC Biosensor

Authors: De Marchi, Elena, Orioli, Elisa, Pegoraro, Anna, Adinolfi, Elena, Di Virgilio, Francesco

Source: Methods in molecular biology. 2041:183-196

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN622105857&indx=1&recIds=ETOCRN622105857

Preclinical and clinical aspects of P2X receptors as a common route in different diseases: A meeting report.

Authors: Tattersall, Luke, Adinolfi, Elena, Antonioli, Luca, Agrawal, Ankita

Source: Purinergic Signalling; Oct2024, Vol. 20 Issue 5, p473-476, 4p

The P2X7 receptor: A main player in inflammation

Authors: Adinolfi, Elena, Giuliani, Anna Lisa, De Marchi, Elena, Pegoraro, Anna, Orioli, Elisa, Di Virgilio, Francesco

Source: In Biochemical Pharmacology May 2018 151:234-244

Amyloid β-dependent mitochondrial toxicity in mouse microglia requires P2X7 receptor expression and is prevented by nimodipine

Authors: Chiozzi, Paola, Sarti, Alba, Sanz, Juana, Giuliani, Anna, Adinolfi, Elena, Vultaggio-Poma, Valentina, Falzoni, Simonetta, Di Virgilio, Francesco

Source: Scientific reports. 9(1):1-15

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100133349561.0x000001&indx=1&recIds=ETOCvdc_100133349561.0x000001

Involvement of P2X7 Receptors in the Osteogenic Differentiation of Mesenchymal Stromal/Stem Cells Derived from Human Subcutaneous Adipose Tissue

Authors: Carluccio, Marzia, Zuccarini, Mariachiara, Ziberi, Sihana, Giuliani, Patricia, Morabito, Caterina, Mariggiò, Maria A., Lonardo, Maria Teresa, Adinolfi, Elena, Orioli, Elisa, Di Iorio, Patrizia, Caciagli, Francesco, Ciccarelli, Renata

Source: Stem cell reviews. 15(4):574-589

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100128554495.0x000001&indx=1&recIds=ETOCvdc_100128554495.0x000001

The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment

Authors: De Marchi, Elena, Orioli, Elisa, Pegoraro, Anna, Sangaletti, Sabina, Portararo, Paola, Curti, Antonio, Colombo, Mario, Di Virgilio, Francesco, Adinolfi, Elena

Source: Oncogene. 38(19):3636-3650

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100188106728.0x000001&indx=1&recIds=ETOCvdc_100188106728.0x000001

The P2X7 Receptor is a Master Regulator of Microparticle and Mitochondria Exchange in Mouse Microglia.

Authors: Falzoni, Simonetta, Vultaggio-Poma, Valentina, Chiozzi, Paola, Tarantini, Mario, Adinolfi, Elena, Boldrini, Paola, Giuliani, Anna Lisa, Morciano, Giampaolo, Tang, Yong, Gorecki, Dariusz C, Di Virgilio, Francesco

Source: Function; 2024, Vol. 5 Issue 4, p1-16, 16p

Subject Terms: ENERGY levels (Quantum mechanics), CELL communication, ENERGY transfer, MITOCHONDRIA, CELL lines

P2X7 Variants in Pathophysiology.

Authors: Pegoraro, Anna, Grignolo, Marianna, Ruo, Luigia, Ricci, Ludovica, Adinolfi, Elena

Source: International Journal of Molecular Sciences; Jun2024, Vol. 25 Issue 12, p6673, 11p

Subject Terms: ALTERNATIVE RNA splicing, PATHOLOGICAL physiology, ADENOSINE triphosphate, PSYCHOLOGICAL stress, SINGLE nucleotide polymorphisms

The purinergic receptor P2X7 as a modulator of viral vector-mediated antigen cross-presentation.

Authors: Longo, Ylenia, Moreno Mascaraque, Sara, Andreacchio, Giuseppe, Werner, Julia, Katahira, Ichiro, De Marchi, Elena, Pegoraro, Anna, Lebbink, Robert Jan, Köhrer, Karl, Petzsch, Patrick, Tao, Ronny, Di Virgilio, Francesco, Adinolfi, Elena, Drexler, Ingo

Source: Frontiers in Immunology; 5/6/2024, p01-18, 18p

Subject Terms: VIRAL antigens, PURINERGIC receptors, VACCINIA, MAJOR histocompatibility complex, DENDRITIC cells

Emerging Roles of Purinergic Signaling in Diabetes

Authors: Fotino, Carmen, Dal Ben, Diego, Adinolfi, Elena

Source: Medicinal chemistry. 14(5):428-438

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100078009897.0x000001&indx=1&recIds=ETOCvdc_100078009897.0x000001

Extracellular ATP and P2 purinergic signalling in the tumour microenvironment

Authors: Di Virgilio, Francesco, Sarti, Alba, Falzoni, Simonetta, De Marchi, Elena, Adinolfi, Elena

Source: Nature reviews.Cancer. 18(10):601-618

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100183817274.0x000001&indx=1&recIds=ETOCvdc_100183817274.0x000001

P2 receptors in cancer progression and metastatic spreading

Authors: Di Virgilio, Francesco, Falzoni, Simonetta, Giuliani, Anna Lisa, Adinolfi, Elena

Source: In Current Opinion in Pharmacology August 2016 29:17-25

Astrocytes‐derived extracellular vesicles in motion at the neuron surface: Involvement of the prion protein

Authors: D'Arrigo, Giulia, Gabrielli, Martina, Scaroni, Federica, Swuec, Paolo, Amin, Ladan, Pegoraro, Anna, Adinolfi, Elena, Di Virgilio, Francesco, Cojoc, Dan, Legname, Giuseppe, Verderio, Claudia

Source: Journal of extracellular vesicles. 10(9)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100132342336.0x000001&indx=1&recIds=ETOCvdc_100132342336.0x000001

P2X7 Receptor Orchestrates Multiple Signalling Pathways Triggering Inflammation, Autophagy and Metabolic/Trophic Responses

Authors: Orioli, Elisa, Marchi, Elena De, Giuliani, Anna Lisa, Adinolfi, Elena

Source: Current medicinal chemistry. 24(21):2261-2275

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100077932588.0x000001&indx=1&recIds=ETOCvdc_100077932588.0x000001

P2X7 Receptor as a Therapeutic Target

Authors: De Marchi, Elena, Orioli, Elisa, Ben, Diego Dal, Adinolfi, Elena

Source: Advances in protein chemistry and structural biology. 104:39-80

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN606530145&indx=1&recIds=ETOCRN606530145