Hepatitis C virus drugs that inhibit SARS-CoV-2 papain-like protease synergize with remdesivir to suppress viral replication in cell culture

Authors: Bafna, Khushboo, White, Kris, Harish, Balasubramanian, Rosales, Romel, Ramelot, Theresa A., Acton, Thomas B., Moreno, Elena, Kehrer, Thomas, Miorin, Lisa, Royer, Catherine A., García-Sastre, Adolfo, Krug, Robert M., Montelione, Gaetano T.

Source: In Cell Reports 18 May 2021 35(7)

Structural and Biochemical Studies Identify Tobacco SABP2 as a Methyl Salicylate Esterase and Implicate It in Plant Innate Immunity

Authors: Forouhar, Farhad, Yang, Yue, Kumar, Dhirendra, Chen, Yang, Fridman, Eyal, Park, Sang Wook, Chiang, Yiwen, Acton, Thomas B., Montelione, Gaetano T., Pichersky, Eran, Klessig, Daniel F., Tong, Liang, Cashmore, Anthony R.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2005 Feb 01. 102(5), 1773-1778.

Access URL: https://www.jstor.org/stable/3374506

The RAS-Binding Domain of Human BRAF Protein Serine/Threonine Kinase Exhibits Allosteric Conformational Changes upon Binding HRAS

Authors: Aramini, James M., Vorobiev, Sergey M., Tuberty, Lynda M., Janjua, Haleema, Campbell, Elliot T., Seetharaman, Jayaraman, Su, Min, Huang, Yuanpeng J., Acton, Thomas B., Xiao, Rong, Tong, Liang, Montelione, Gaetano T.

Source: In Structure 4 August 2015 23(8):1382-1393

High-Throughput Production of Proteins in E. coli for Structural Studies

Authors: Black, Charikleia, Barker, John J., Hitchman, Richard B., Kwong, Hok Sau, Festenstein, Sam, Acton, Thomas B.

Source: Methods in molecular biology. 1586:359-372

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN611403730&indx=1&recIds=ETOCRN611403730

Crystal Structures of Malonyl-Coenzyme A Decarboxylase Provide Insights into Its Catalytic Mechanism and Disease-Causing Mutations

Authors: Froese, D. Sean, Forouhar, Farhad, Tran, Timothy H., Vollmar, Melanie, Kim, Yi Seul, Lew, Scott, Neely, Helen, Seetharaman, Jayaraman, Shen, Yang, Xiao, Rong, Acton, Thomas B., Everett, John K., Cannone, Giuseppe, Puranik, Sriharsha, Savitsky, Pavel, Krojer, Tobias, Pilka, Ewa S., Kiyani, Wasim, Lee, Wen Hwa, Marsden, Brian D., von Delft, Frank, Allerston, Charles K., Spagnolo, Laura, Gileadi, Opher, Montelione, Gaetano T., Oppermann, Udo, Yue, Wyatt W., Tong, Liang

Source: In Structure 2 July 2013 21(7):1182-1192

A hybrid NMR/SAXS‐based approach for discriminating oligomeric protein interfaces using Rosetta

Authors: Rossi, Paolo, Shi, Lei, Liu, Gaohua, Barbieri, Christopher M., Lee, Hsiau‐Wei, Grant, Thomas D., Luft, Joseph R., Xiao, Rong, Acton, Thomas B., Snell, Edward H., Montelione, Gaetano T., Baker, David, Lange, Oliver F., Sgourakis, Nikolaos G.

Source: Proteins. 83(2):309-317

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100085835860.0x000001&indx=1&recIds=ETOCvdc_100085835860.0x000001

Determination of solution structures of proteins up to 40 kDa using CS-Rosetta with sparse NMR data from deuterated samples

Authors: Lange, Oliver F., Rossi, Paolo, Sgourakis, Nikolaos G., Song, Yifan, Lee, Hsiau-Wei, Aramini, James M., Ertekin, Asli, Xiao, Rong, Acton, Thomas B., Montelione, Gaetano T., Baker, David

Source: Proceedings of the National Academy of Sciences of the United States of America, 2012 Jul 01. 109(27), 10873-10878.

Access URL: https://www.jstor.org/stable/41601697

Novel C-terminal Motif within Sec7 Domain of Guanine Nucleotide Exchange Factors Regulates ADP-ribosylation Factor (ARF) Binding and Activation

Authors: Lowery, Jason, Szul, Tomasz, Seetharaman, Jayaraman, Jian, Xiaoying, Su, Min, Forouhar, Farhad, Xiao, Rong, Acton, Thomas B., Montelione, Gaetano T., Lin, Helen, Wright, John W., Lee, Eunjoo, Holloway, Zoe G. ^**, Randazzo, Paul A., Tong, Liang, Sztul, Elizabeth

Source: In Journal of Biological Chemistry 21 October 2011 286(42):36898-36906

Molecular Insights into Substrate Recognition and Catalysis by Tryptophan 2,3-Dioxygenase

Authors: Forouhar, Farhad, Anderson, J. L. Ross, Mowat, Christopher G., Vorobiev, Sergey M., Hussain, Arif, Abashidze, Mariam, Bruckmann, Chiara, Thackray, Sarah J., Seetharaman, Jayaraman, Tucker, Todd, Xiao, Rong, Ma, Li-Chung, Zhao, Li, Acton, Thomas B., Montelione, Gaetano T., Chapman, Stephen K., Tong, Liang

Source: Proceedings of the National Academy of Sciences of the United States of America, 2007 Jan 01. 104(2), 473-478.

Access URL: https://www.jstor.org/stable/25426126

The high-throughput protein sample production platform of the Northeast Structural Genomics Consortium

Authors: Xiao, Rong, Anderson, Stephen, Aramini, James, Belote, Rachel, Buchwald, William A., Ciccosanti, Colleen, Conover, Ken, Everett, John K., Hamilton, Keith, Huang, Yuanpeng Janet, Janjua, Haleema, Jiang, Mei, Kornhaber, Gregory J., Lee, Dong Yup, Locke, Jessica Y., Ma, Li-Chung, Maglaqui, Melissa, Mao, Lei, Mitra, Saheli, Patel, Dayaban, Rossi, Paolo, Sahdev, Seema, Sharma, Seema, Shastry, Ritu, Swapna, G.V.T., Tong, Saichu N., Wang, Dongyan, Wang, Huang, Zhao, Li, Montelione, Gaetano T., Acton, Thomas B.

Source: In Journal of Structural Biology October 2010 172(1):21-33

Structural Basis of O6-Alkylguanine Recognition by a Bacterial Alkyltransferase-like DNA Repair Protein

Authors: Aramini, James M., Tubbs, Julie L., Kanugula, Sreenivas, Rossi, Paolo, Ertekin, Asli, Maglaqui, Melissa, Hamilton, Keith, Ciccosanti, Colleen T., Jiang, Mei, Xiao, Rong, Soong, Ta-Tsen, Rost, Burkhard, Acton, Thomas B., Everett, John K., Pegg, Anthony E., Tainer, John A. ^**, Montelione, Gaetano T.

Source: In Journal of Biological Chemistry 30 April 2010 285(18):13736-13741

Structure function characterization of SARS CoV2 proteases for COVID19 antiviral development

Authors: Greene-Cramer, Rebecca, Bafna, Khushboo, White, Kris, Harish, Balasubramanian, Rosales, Romel, Ramelot, Theresa, Acton, Thomas B., Del Olmo, Elena Moreno, Kehrer, Thomas, Miorin, Lisa, Royer, Catherine A., Garcia-Sastre, Adolfo, Krug, Robert, Montelione, Gaetano T.

Source: Biophysical journal. 121(S1):30a-30a

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100177561286.0x000001&indx=1&recIds=ETOCvdc_100177561286.0x000001

Molecular Insights into the Biosynthesis of the F420 Coenzyme

Authors: Forouhar, Farhad, Abashidze, Mariam, Xu, Huimin, Grochowski, Laura L., Seetharaman, Jayaraman, Hussain, Munif, Kuzin, Alexandre, Chen, Yang, Zhou, Weihong, Xiao, Rong, Acton, Thomas B., Montelione, Gaetano T., Galinier, Anne, White, Robert H., Tong, Liang

Source: In Journal of Biological Chemistry 25 April 2008 283(17):11832-11840

Structural and Functional Studies of the Abundant Tegument Protein ORF52 from Murine Gammaherpesvirus 68

Authors: Benach, Jordi, Wang, Lili, Chen, Yang, Ho, Chi Kent, Lee, Shaoying, Seetharaman, Jayaraman, Xiao, Rong, Acton, Thomas B., Montelione, Gaetano T., Deng, Hongyu, Sun, Ren, Tong, Liang

Source: In Journal of Biological Chemistry 26 October 2007 282(43):31534-31541

Crystal Structures of Two Bacterial 3-Hydroxy-3-methylglutaryl-CoA Lyases Suggest a Common Catalytic Mechanism among a Family of TIM Barrel Metalloenzymes Cleaving Carbon-Carbon Bonds

Authors: Forouhar, Farhad, Hussain, Munif, Farid, Ramy, Benach, Jordi, Abashidze, Mariam, Edstrom, William C., Vorobiev, Sergey M., Xiao, Rong, Acton, Thomas B., Fu, Zhuji, Kim, Jung-Ja P., Miziorko, Henry M., Montelione, Gaetano T., Hunt, John F.

Source: In Journal of Biological Chemistry 17 March 2006 281(11):7533-7545

Protocol for production and purification of SARS-CoV-2 3CLpro

Authors: Mazzei, Luca, Greene-Cramer, Rebecca, Bafna, Khushboo, Jovanovic, Aleksandar, De Falco, Anna, Acton, Thomas B., Royer, Catherine Ann, Ciurli, Stefano, Montelione, Gaetano T.

Source: In STAR Protocols 16 June 2023 4(2)

Structural and Functional Evidence for Bacillus subtilis PaiA as a Novel N1-Spermidine/Spermine Acetyltransferase

Authors: Forouhar, Farhad ^‡, Lee, In-Sun ^‡, Vujcic, Jelena ^§, Vujcic, Slavoljub ^§, Shen, Jianwei ^‡, Vorobiev, Sergey M. ^‡, Xiao, Rong ^{¶, ∥}, Acton, Thomas B. ^{¶, ∥}, Montelione, Gaetano T. ^{¶, ∥}, Porter, Carl W. ^§, Tong, Liang ^{‡, 1}

Source: In Journal of Biological Chemistry 2 December 2005 280(48):40328-40336

Robotic Cloning and Protein Production Platform of the Northeast Structural Genomics Consortium

Authors: Acton, Thomas B., Gunsalus, Kristin C., Xiao, Rong, Ma, Li Chung, Aramini, James, Baran, Michael C., Chiang, Yi-Wen, Climent, Teresa, Cooper, Bonnie, Denissova, Natalia G., Douglas, Shawn M., Everett, John K., Ho, Chi Kent, Macapagal, Daphne, Rajan, Paranji K., Shastry, Ritu, Shih, Liang-yu, Swapna, G.V.T., Wilson, Michael, Wu, Margaret, Gerstein, Mark, Inouye, Masayori, Hunt, John F., Montelione, Gaetano T.

Source: In Methods in Enzymology 2005 394:210-243

A Novel NAD-binding Protein Revealed by the Crystal Structure of 2,3-Diketo-l-gulonate Reductase (YiaK)

Authors: Forouhar, Farhad ^‡, Lee, Insun ^‡, Benach, Jordi ^‡, Kulkarni, Kaushal ^‡, Xiao, Rong ^§, Acton, Thomas B. ^§, Montelione, Gaetano T. ^§, Tong, Liang ^{‡, ¶}

Source: In Journal of Biological Chemistry 26 March 2004 279(13):13148-13155

The SufE Sulfur-acceptor Protein Contains a Conserved Core Structure that Mediates Interdomain Interactions in a Variety of Redox Protein Complexes

Authors: Goldsmith-Fischman, Sharon, Kuzin, Alexandre, Edstrom, William C., Benach, Jordi, Shastry, Ritu, Xiao, Rong, Acton, Thomas B., Honig, Barry, Montelione, Gaetano T., Hunt, John F. ^*

Source: In Journal of Molecular Biology 2004 344(2):549-565