Comparative evaluation of antifungal susceptibility testing methods of invasive Candida species and detection of FKS genes mutations in caspofungin intermediate and resistant isolates

Authors: Dalia Saad ElFeky, Doaa Mahdy El-Wakil, Mai M. Mwafy, Mohamed M.A. Atia, Noha Mahmoud Gohar

Source: BMC Infectious Diseases, Vol 25, Iss 1, Pp 1-16 (2025)

Subject Terms: Candida species, ATB FUNGUS 3, Vitek-2 AST-YS08, Caspofungin, Acquired resistance, FKS mutations, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2334

Access URL: https://doaj.org/article/20ebcbcb82724668a6385969786ca51a

The Use of Personalized Medicine in Pancreatic Ductal Adenocarcinoma (PDAC): New Therapeutic Opportunities

Authors: Inês Mendes, Nuno Vale

Source: Future Pharmacology, Vol 4, Iss 4, Pp 934-954 (2024)

Subject Terms: genetics, epigenetics, microbiome-acquired resistance, personalized medicine, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2673-9879/4/4/49; https://doaj.org/toc/2673-9879

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Identification of expression profiles and transcription factors during EGFR‐TKI acquired resistance in LUAD

Authors: Lili Feng, Cenzhu Wang, Jiawen Chen, Chenyue Tao, Liuliu Zhang, Luojing Zhou

Source: Precision Medical Sciences, Vol 13, Iss 4, Pp 221-231 (2024)

Subject Terms: acquired resistance, EGFR‐TKI, LUAD, single‐cell RNA sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2642-2514

Access URL: https://doaj.org/article/3fe99e3aa5a54907baee838121c1a974

Immunomodulating melatonin-decorated silica nanoparticles suppress bacterial wilt (Ralstonia solanacearum) in tomato (Solanum lycopersicum L.) through fine-tuning of oxidative signaling and rhizosphere bacterial community

Authors: Munazza Ijaz, Luqiong Lv, Temoor Ahmed, Muhammad Noman, Abdul Manan, Rafia Ijaz, Rahila Hafeez, Muhammad Shafiq Shahid, Daoze Wang, Gabrijel Ondrasek, Bin Li

Source: Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-22 (2024)

Subject Terms: Biogenic nanoformulations, Microbiome, Plant defense, Systemic acquired resistance, Stress signaling, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/1477-3155

Access URL: https://doaj.org/article/28dd9ebd08634148b3a08690a141d2a4

RNA silencing is activated by N gene-mediated hypersensitive response and plays a key role in local and systemic virus resistance

Authors: Wenjing Li, Ru Yu, Wenjuan Liu, Hong Zhang, Chengyang Ren, Yan Zhang, Haoran Ma, Changxiang Zhu, Hongmei Liu

Source: Phytopathology Research, Vol 6, Iss 1, Pp 1-13 (2024)

Subject Terms: TMV, N gene, RNA silencing, Hypersensitive response, Systemic acquired resistance, Plant culture, SB1-1110

File Description: electronic resource

Relation: https://doaj.org/toc/2524-4167

Access URL: https://doaj.org/article/2837e86cd9854632a37362b5ccf216f8

Disruption of mgrB gene by ISkpn14 sourced from a bla KPC−2 carrying plasmid mediating polymyxin resistance against carbapenem-resistant Klebsiella pneumoniae during treatment: study on the underlying mechanisms

Authors: Ziyao Li, Zichen Lei, Xinmeng Liu, Feilong Zhang, Xinrui Yang, Yongli Wu, Chen Li, Jiankang Zhao, Yulin Zhang, Yanning Hua, Binghuai Lu, Bin Cao

Source: BMC Microbiology, Vol 24, Iss 1, Pp 1-12 (2024)

Subject Terms: Polymyxin resistance, Insertion sequence, Carbapenem-resistant Klebsiella pneumoniae, Acquired resistance, Origination of the IS, Microbiology, QR1-502

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2180

Access URL: https://doaj.org/article/0c01922e3d354ef0bc3e7f59bec75163

Genomic and phenotypic insight into antimicrobial resistance of Pseudomonas fluorescens from King George Island, Antarctica

Authors: Myllena Pereira Silverio, Júnia Schultz, Mariana T. D. Parise, Doglas Parise, Marcus Vinicius Canário Viana, Wylerson Nogueira, Rommel Thiago Jucá Ramos, Aristoteles Góes-Neto, Vasco Ariston De Carvalho Azevedo, Bertram Brenig, Raquel Regina Bonelli, Alexandre Soares Rosado

Source: Frontiers in Microbiology, Vol 16 (2025)

Subject Terms: resistomes, psychrotolerant bacteria, Proteobacteria, Pseudomonadota, antibiotics, acquired resistance, Microbiology, QR1-502

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmicb.2025.1535420/full; https://doaj.org/toc/1664-302X

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Ginseng polysaccharides circumvent acquired resistance to anti-PD-1 immunotherapy in patients with non-small cell lung cancer

Authors: Jumin Huang, Ziming Wang, Feng Li, Huiting Wang, Yang Xiang, Runze Li, Chun Xie, Yuwei Wang, Zhihong Jiang, Yabing Cao, Wenhua Liang, Elaine Lai-Han Leung

Source: Pharmacological Research, Vol 212, Iss , Pp 107611- (2025)

Subject Terms: Immune checkpoint inhibitors, Acquired resistance, Non-small cell lung cancer, Ginseng polysaccharides, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1043661825000362; https://doaj.org/toc/1096-1186

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The control effect and induced disease resistance mechanism of Bacillus tequilensis on wheat powdery mildew

Authors: Qiuyan Bi, Fen Lu, Jie Wu, Xiangyu Liu, Xiuying Han, Jianjiang Zhao

Source: Biological Control, Vol 201, Iss , Pp 105698- (2025)

Subject Terms: Bacillus tequilensis, Blumeria graminis, Systemic acquired resistance, Agriculture, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1049964425000088; https://doaj.org/toc/1049-9644

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Viral diversity and phloem transcriptional changes in grapevine Shiraz disease infected vines

Authors: Cristobal Onetto, Dilrukshi Nagahatenna, Yeniu Mickey Wang, Vinay Pagay, Anthony Borneman

Source: OENO One, Vol 59, Iss 1 (2025)

Subject Terms: Grapevine Shiraz disease, Grapevine Virus A, Grapevine leafroll virus, Systemic Acquired Resistance, Transcriptomics, Agriculture, Botany, QK1-989

File Description: electronic resource

Relation: https://oeno-one.eu/article/view/8284; https://doaj.org/toc/2494-1271

Access URL: https://doaj.org/article/be92e99c8e444c0a9b3741f977cf1f94

In vitro evaluation of the clinical utility of Apitolisib/Vorinostat combination in Apitolisib-resistant H1975 lung adenocarcinoma cells

Authors: Abduladim Hmmier, Paul Dowling

Source: Future Journal of Pharmaceutical Sciences, Vol 10, Iss 1, Pp 1-10 (2024)

Subject Terms: H1975 lung adenocarcinoma, Apitolisib-acquired resistance, Acquired aggressive proliferation, Metabolic reprogramming, Apitolisib/Vorinostat combination, Therapeutics. Pharmacology, RM1-950, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://doaj.org/toc/2314-7253

Access URL: https://doaj.org/article/9e4cd27a9c7d4f3aa45a2f3d06206ab1

Insights into gemcitabine resistance in pancreatic cancer: association with metabolic reprogramming and TP53 pathogenicity in patient derived xenografts

Authors: Mariam M. Konaté, Julia Krushkal, Ming-Chung Li, Li Chen, Yuri Kotliarov, Alida Palmisano, Rini Pauly, Qian Xie, P. Mickey Williams, Lisa M. McShane, Yingdong Zhao

Source: Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)

Subject Terms: Pancreatic adenocarcinoma, Gemcitabine, Intrinsic resistance, Acquired resistance, OXPHOS, Glycolysis, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1479-5876

Access URL: https://doaj.org/article/8450290fb1bd45a187afecbd4534732f

New insights into azelaic acid-induced resistance against Alternaria Solani in tomato plants

Authors: Mostafa Haghpanah, Nadali Babaeian Jelodar, Hamid Najafi Zarrini, Ali Pakdin-Parizi, Ali Dehestani

Source: BMC Plant Biology, Vol 24, Iss 1, Pp 1-14 (2024)

Subject Terms: Defense response, JA/ET pathway, Necrotrophic pathogen, Phytohormone analysis, Systemic acquired resistance, Botany, QK1-989

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2229

Access URL: https://doaj.org/article/e650bacfd5244840b98d5d3ef4efdd1d

Genomic landscape of clinically acquired resistance alterations in patients treated with KRASG12C inhibitors

Authors: Riedl, J.M. ^{1, 2, †}, Fece de la Cruz, F. ^{1, †}, Lin, J.J. ¹, Parseghian, C. ², Kim, J.E. ^{1, 3}, Matsubara, H. ¹, Barnes, H. ¹, Caughey, B. ¹, Norden, B.L. ¹, Morales-Giron, A.A. ¹, Kushner, E.W. ¹, Ehnstrom, S. ¹, Nakamura, H. ¹, Patel, P.S. ¹, Ellis, H. ¹, Pappas, L. ¹, Vakaris, A. ¹, Gainor, J.F. ¹, Kopetz, S. ², Klempner, S.J. ¹, Parikh, A.R. ¹, Hata, A.N. ¹, Heist, R.S. ¹, Corcoran, R.B. ^{1, ∗}

Source: In Annals of Oncology

Treatment Patterns and Clinical Outcomes in Patients With EGFR-Mutated Non–Small-Cell Lung Cancer After Progression on Osimertinib

Authors: Robinson, Nathaniel D. ¹, Canavan, Maureen E. ¹, Zhan, Peter L. ¹, Udelsman, Brooks V. ², Pathak, Ranjan ³, Boffa, Daniel J. ¹, Goldberg, Sarah B. ^{1, ⁎}

Source: In Clinical Lung Cancer January 2025 26(1):9-17

Acquired gene alterations in patients treated with ribociclib plus endocrine therapy or endocrine therapy alone using baseline and end-of-treatment circulating tumor DNA samples in the MONALEESA-2, -3, and -7 trials

Authors: André, F. ^{1, ∗}, Solovieff, N. ², Su, F. ³, Bardia, A. ⁴, Neven, P. ⁵, Yap, Y.S. ⁶, Tripathy, D. ⁷, Lu, Y.-S. ⁸, Slamon, D. ⁹, Chia, S. ¹⁰, Joshi, M. ², Chakravartty, A. ³, Lteif, A. ³, Taran, T. ¹¹, Arteaga, C.L. ^{12, ∗}

Source: In Annals of Oncology January 2025 36(1):54-64

A good response to furmonertinib fourth-line treatment of an advanced lung adenocarcinoma patient with EGFR exon20in and PIK3CA mutation: a case report and literature review

Authors: Kai Sun, Peng Wang

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: EGFR-TKI, PIK3CA mutant, furmonertinib, synchronous cancer, EGFR-TKI acquired resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1467722/full; https://doaj.org/toc/2234-943X

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Corrigendum: Bruceine H mediates EGFR-TKI drug persistence in NSCLC by Notch3-dependent β-catenin activating FOXO3a signaling

Authors: Jiahui Wu, Xiao He, Ziwei Xiong, Lingyu Shi, Daofeng Chen, Yulin Feng, Quan Wen

Source: Frontiers in Oncology, Vol 14 (2024)

Subject Terms: bruceine H, Notch3 inhibitor, EGFR-TKI, acquired resistance, non-small cell lung cancer, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2024.1515205/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/4d21ae32d5c241e190039fbf8d9293c6

EGFR bypass activation mediates acquired resistance to regorafenib in hepatocellular carcinoma

Authors: Lili Hu, Weiwei Shi, Kua Liu, Ding Ma, Qilei Xin, Zhongxia Wang, Yin Cao, Guang Zhang

Source: Frontiers in Medicine, Vol 11 (2024)

Subject Terms: regorafenib, acquired resistance, EGFR, bypass activation, combination therapy, HCC, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmed.2024.1464610/full; https://doaj.org/toc/2296-858X

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Neuroendocrine transdifferentiation in human cancer: molecular mechanisms and therapeutic targets

Authors: Jun Jiang, Donghui Han, Jiawei Wang, Weihong Wen, Rui Zhang, Weijun Qin

Source: MedComm, Vol 5, Iss 10, Pp n/a-n/a (2024)

Subject Terms: acquired resistance, lineage plasticity, neuroendocrine prostate cancer, neuroendocrine transdifferentiation, small cell lung cancer, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2688-2663

Access URL: https://doaj.org/article/cde92fc00e854d8b971b3bc3cb137a13