Safety, Virology, Pharmacokinetics, and Clinical Experience of High-Dose Intravenous Sotrovimab for the Treatment of Mild to Moderate COVID-19: An Open-Label Clinical Trial.

Authors: Moya, Jaynier, Temech, Marisol, Parra, Sergio, Juarez, Erick, Hernandez-Loy, Reinaldo, Gutierrez, Juan C Moises, Diaz, Jorge, Hussain, Rubaba, Segal, Scott, Xu, Claire, Skingsley, Andrew, Schnell, Gretja, El-Zailik, Asma, Sager, Jennifer E, Aldinger, Melissa, Alexander, Elizabeth L, Acloque, Gerard

Source: Open Forum Infectious Diseases; Jul2023, Vol. 10 Issue 7, p1-8, 8p

Subject Terms: COVID-19, VIROLOGY, CLINICAL trials, COUGH, PHARMACOKINETICS, VIRAL load, MYOCARDIAL infarction

Geographic Terms: UNITED States

IRAK4 degrader in hidradenitis suppurativa and atopic dermatitis: a phase 1 trial

Authors: Ackerman, Lindsay, Acloque, Gerard, Bacchelli, Sandro, Schwartz, Howard, Feinstein, Brian J., La Stella, Phillip, Alavi, Afsaneh, Gollerkeri, Ashwin, Davis, Jeffrey, Campbell, Veronica, McDonald, Alice, Agarwal, Sagar, Karnik, Rahul, Shi, Kelvin, Mishkin, Aimee, Culbertson, Jennifer, Klaus, Christine, Enerson, Bradley, Massa, Virginia, Kuhn, Eric, Sharma, Kirti, Keaney, Erin, Barnes, Randy, Chen, Dapeng, Zheng, Xiaozhang, Rong, Haojing, Sabesan, Vijay, Ho, Chris, Mainolfi, Nello, Slavin, Anthony, Gollob, Jared A.

Source: Nature Medicine; 20230101, Issue: Preprints p1-10, 10p

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