Dual TLR9 and PD-L1 targeting unleashes dendritic cells to induce durable antitumor immunity

Authors: Alfred Zippelius, Mélanie Buchi, Richard Klar, Julia Festag, Sven Michel, Frank Jaschinski, Sebastian Kobold, Abhishek S Kashyap, Johannes vom Berg, Laura Fernandez-Rodriguez, Chiara Cianciaruso, Ruben Bill, Marcel P Trefny, Nicole Kirchhammer, Rainer H Kohler, Elham Jones, Andre Maaske, Karen O Dixon, Mikael J Pittet

Source: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 5 (2023)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/11/5/e006714.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/78cf6c8515374d7f847b8913a986bde6

Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer

Authors: Alfred Zippelius, Petra Herzig, Heinz Läubli, Vaios Karanikas, Gieri Cathomas, Christian Klein, Marta Trüb, Franziska Uhlenbrock, Christina Claus, Martin Thelen, Marina Bacac, Maria Amann, Rosemarie Albrecht, Claudia Ferrara-Koller, Daniela Thommen, Sacha Rothschield, Spasenija Savic Prince, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Abhishek S Kashyap

Source: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)

Subject Terms: Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://jitc.bmj.com/content/8/2/e000238.full; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/812e0e185e314e829d4e8fe6aa67b3da

Plinabulin, a Distinct Microtubule-Targeting Chemotherapy, Promotes M1-Like Macrophage Polarization and Anti-tumor Immunity

Authors: Marina Natoli, Petra Herzig, Elham Pishali Bejestani, Melanie Buchi, Reto Ritschard, G. Kenneth Lloyd, Ramon Mohanlal, James R. Tonra, Lan Huang, Viola Heinzelmann, Marta Trüb, Alfred Zippelius, Abhishek S. Kashyap

Source: Frontiers in Oncology, Vol 11 (2021)

Subject Terms: immunoncology, macrophage polarization, anti-tumor immunity, ovarian cancer, chemotherapy, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fonc.2021.644608/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/d21b4ca37c104d1593f619178ef9f5c2

Antisense oligonucleotide targeting CD39 improves anti-tumor T cell immunity

Authors: Abhishek S. Kashyap, Tamara Thelemann, Richard Klar, Sandra M. Kallert, Julia Festag, Melanie Buchi, Lisa Hinterwimmer, Monika Schell, Sven Michel, Frank Jaschinski, Alfred Zippelius

Source: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-12 (2019)

Subject Terms: CD39, CD73, Ectonucleotidase, Antisense oligonucleotide (ASO), Immunotherapy, ATP, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s40425-019-0545-9; https://doaj.org/toc/2051-1426

Access URL: https://doaj.org/article/270e5351314041b4b9b45ed11b5860ce

GEF-H1 Signaling upon Microtubule Destabilization Is Required for Dendritic Cell Activation and Specific Anti-tumor Responses

Authors: Abhishek S. Kashyap, Laura Fernandez-Rodriguez, Yun Zhao, Gianni Monaco, Marcel P. Trefny, Naohiro Yoshida, Kea Martin, Ashwani Sharma, Natacha Olieric, Pankaj Shah, Michal Stanczak, Nicole Kirchhammer, Sung-Moo Park, Sebastien Wieckowski, Heinz Laubli, Rachid Zagani, Benjamin Kasenda, Michel O. Steinmetz, Hans-Christian Reinecker, Alfred Zippelius

Source: Cell Reports, Vol 28, Iss 13, Pp 3367-3380.e8 (2019)

Subject Terms: Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211124719311052; https://doaj.org/toc/2211-1247

Access URL: https://doaj.org/article/21a0d97cff3b46a0a90aae9154512253