ATDC is required for the initiation of KRAS-induced pancreatic tumorigenesis

Authors: Wang, Lidong, Yang, Huibin, Zamperone, Andrea, Diolaiti, Daniel, Palmbos, Phillip L., Abel, Ethan V., Purohit, Vinee, Dolgalev, Igor, Rhim, Andrew D., Ljungman, Mats

Source: Genes & development. 33(11/12):641-655

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN620460022&indx=1&recIds=ETOCRN620460022

Biology and Clinical Applications of Pancreatic Cancer Stem Cells

Authors: Abel, Ethan V., Simeone, Diane M.

Source: In Gastroenterology June 2013 144(6):1241-1248

Beta 1 integrin signaling mediates pancreatic ductal adenocarcinoma resistance to MEK inhibition

Authors: Brannon, Arthur, Drouillard, Donovan, Steele, Nina, Schoettle, Shadae, Abel, Ethan V., Crawford, Howard C., Pasca di Magliano, Marina

Source: Scientific reports. 10(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100174576705.0x000001&indx=1&recIds=ETOCvdc_100174576705.0x000001

SHOC2 and CRAF Mediate ERK1/2 Reactivation in Mutant NRAS-mediated Resistance to RAF Inhibitor

Authors: Kaplan, Fred M., Kugel, Curtis H., III, Dadpey, Neda, Shao, Yongping, Abel, Ethan V., Aplin, Andrew E.

Source: In Journal of Biological Chemistry 7 December 2012 287(50):41797-41807

GSK3β Inhibition Blocks Melanoma Cell/Host Interactions by Downregulating N-Cadherin Expression and Decreasing FAK Phosphorylation

Authors: John, Jobin K. ¹, Paraiso, Kim H.T. ¹, Rebecca, Vito W. ¹, Cantini, Liliana P. ¹, Abel, Ethan V. ², Pagano, Nicholas ^{3, 4}, Meggers, Eric ^{3, 4}, Mathew, Rahel ⁵, Krepler, Clemens ⁶, Izumi, Victoria ⁷, Fang, Bin ⁷, Koomen, John M. ¹, Messina, Jane L. ⁵, Herlyn, Meenhard ⁶, Smalley, Keiran S.M. ^{1, 8, *}

Source: In Journal of Investigative Dermatology December 2012 132(12):2818-2827

A homing endonuclease and the 50-nt ribosomal bypass sequence of phage T4 constitute a mobile DNA cassette

Authors: Bonocora, Richard P., Zeng, Qinglu, Abel, Ethan V., Shub, David A.

Source: Proceedings of the National Academy of Sciences of the United States of America, 2011 Sep . 108(39), 16351-16356.

Access URL: https://www.jstor.org/stable/41352802

Cyclin D3 Expression in Melanoma Cells Is Regulated by Adhesion-dependent Phosphatidylinositol 3-Kinase Signaling and Contributes to G1-S Progression

Authors: Spofford, Laurie S., Abel, Ethan V., Boisvert-Adamo, Karen, Aplin, Andrew E.

Source: In Journal of Biological Chemistry 1 September 2006 281(35):25644-25651

The Notch Pathway Is Important in Maintaining the Cancer Stem Cell Population in Pancreatic Cancer.

Authors: Abel, Ethan V.¹, Kim, Edward J.², Wu, Jingjiang¹, Hynes, Mark¹, Bednar, Filip¹, Proctor, Erica¹, Wang, Lidong¹, Dziubinski, Michele L.¹, Simeone, Diane M.^1,3,4 simeone@umich.edu

Source: PLoS ONE. Mar2014, Vol. 9 Issue 3, p1-13. 13p.

Subject Terms: *STEM cells, *CELL populations, *PANCREATIC cancer, *CANCER cells, *LABORATORY mice, *CYTOLOGY, *GASTROENTEROLOGY, *HEPATOLOGY

Promise, Paradox, and Problems: Vemurafenib, a Melanoma Game Changer.

Authors: Abel, Ethan V.¹, Kugel III, Curtis H.¹, Aplin, Andrew E.^1,2 andrew.aplin@kimmelcancercenter.org

Source: Current Medical Literature: Dermatology. 2012, Vol. 17 Issue 4, p89-98. 10p. 1 Diagram.

Subject Terms: *MELANOMA treatment, *SKIN cancer, *ONCOGENES, *ONCOLOGY, *DERMATOLOGY

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ATDC binds to KEAP1 to drive NRF2-mediated tumorigenesis and chemoresistance in pancreatic cancer

Authors: Purohit, Vinee, Wang, Lidong, Yang, Huibin, Li, Jiufeng, Ney, Gina M., Gumkowski, Erica R., Vaidya, Akash J., Wang, Annie, Bhardwaj, Amit, Zhao, Ende, Dolgalev, Igor, Zamperone, Andrea, Abel, Ethan V., Magliano, Marina Pasca Di, Crawford, Howard C., Diolaiti, Daniel, Papagiannakopoulos, Thales Y., Lyssiotis, Costas A., Simeone, Diane M.

Source: Genes & Development; 2021, Vol. 35 Issue: 3-4 p218-233, 16p

A surgical orthotopic approach for studying the invasive progression of human bladder cancer.

Authors: Lorenzatti Hiles, Guadalupe, Cates, Angelica L., El-Sawy, Layla, Day, Kathleen C., Broses, Luke J., Han, Amy L., Briggs, Hannah L., Emamdjomeh, Amir, Chou, Andrew, Abel, Ethan V., Liebert, Monica, Palmbos, Phillip L., Udager, Aaron M., Keller, Evan T., Day, Mark L.

Source: Nature Protocols; Mar2019, Vol. 14 Issue 3, p738-755, 18p

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ATDC mediates a TP63-regulated basal cancer invasive program

Authors: Palmbos, Phillip L., Wang, Yin, Bankhead III, Armand, Kelleher, Alan J., Wang, Lidong, Yang, Huibin, Ahmet, McKenzie L., Gumkowski, Erica R., Welling, Samuel D., Magnuson, Brian, Leflein, Jacob, Lorenzatti Hiles, Guadalupe, Abel, Ethan V., Dziubinski, Michele L., Urs, Sumithra, Day, Mark L., Ljungman, Mats E., Simeone, Diane M.

Source: Oncogene; May 2019, Vol. 38 Issue: 18 p3340-3354, 15p

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