Sall4 and Gata4 induce cardiac fibroblast transition towards a partially multipotent state with cardiogenic potential

Authors: Hong Gao, Saliha Pathan, Beverly R. E. A. Dixon, Aarthi Pugazenthi, Megumi Mathison, Tamer M.A. Mohamed, Todd K. Rosengart, Jianchang Yang

Source: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)

Subject Terms: Cardiac regeneration, Pluripotency, Partial reprogramming, Sox17, Oct4, Protein interaction, Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/dddb22f9f6054e26a9612826b2a513e0

Activation of a GPCR, ORL1 Receptor: A Novel Therapy to Prevent Heart Failure Progression

Authors: Saliha S. Pathan, Aarthi Pugazenthi, Beverly R. E. A. Dixon, Theodore G. Wensel, Todd K. Rosengart, Megumi Mathison

Source: Journal of Cardiovascular Development and Disease, Vol 11, Iss 11, p 355 (2024)

Subject Terms: prevention of ischemic heart failure progression, ORL1 receptor activation, MCOPPB, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://www.mdpi.com/2308-3425/11/11/355; https://doaj.org/toc/2308-3425

Access URL: https://doaj.org/article/be5a8326140a4065aaf1f0c4db5dff10

p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation

Authors: Jaya Pratap Pinnamaneni, Vivek P. Singh, Mary B. Kim, Christopher T. Ryan, Aarthi Pugazenthi, Deepthi Sanagasetti, Megumi Mathison, Jianchang Yang, Todd K. Rosengart

Source: Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/134bd79bdf1646b48043120e2ac5e255

Fibroblast transition to an endothelial 'trans' state improves cell reprogramming efficiency

Authors: Megumi Mathison, Deepthi Sanagasetti, Vivek P. Singh, Aarthi Pugazenthi, Jaya Pratap Pinnamaneni, Christopher T. Ryan, Jianchang Yang, Todd K. Rosengart

Source: Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/dd218c69e5e94d91a0439e753722da4a

Hippo Pathway Effector Tead1 Induces Cardiac Fibroblast to Cardiomyocyte Reprogramming

Authors: Vivek P. Singh, Jaya P. Pinnamaneni, Aarthi Pugazenthi, Deepthi Sanagasetti, Megumi Mathison, James F. Martin, Jianchang Yang, Todd K. Rosengart

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 24 (2021)

Subject Terms: cardiomyocytes, direct reprogramming, regeneration, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/03a8a14f7f4f4a2bbb8a18395c5c2fe4

Enhanced Generation of Induced Cardiomyocytes Using a Small‐Molecule Cocktail to Overcome Barriers to Cardiac Cellular Reprogramming

Authors: Vivek P. Singh, Jaya Pratap Pinnamaneni, Aarthi Pugazenthi, Deepthi Sanagasetti, Megumi Mathison, Kai Wang, Jianchang Yang, Todd K. Rosengart

Source: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 12 (2020)

Subject Terms: cardiomyocytes, direct reprogramming, small molecules, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/2047-9980

Access URL: https://doaj.org/article/1040bbb45c734eb0ad10c5511adb548e