Glucose-dependent insulinotropic polypeptide (GIP)

Authors: Timo D. Müller, Alice Adriaenssens, Bo Ahrén, Matthias Blüher, Andreas L. Birkenfeld, Jonathan E. Campbell, Matthew P. Coghlan, David D'Alessio, Carolyn F. Deacon, Stefano DelPrato, Jonathan D. Douros, Daniel J. Drucker, Natalie S. Figueredo Burgos, Peter R. Flatt, Brian Finan, Ruth E. Gimeno, Fiona M. Gribble, Matthew R. Hayes, Christian Hölscher, Jens J. Holst, Patrick J. Knerr, Filip K. Knop, Christine M. Kusminski, Arkadiusz Liskiewicz, Guillaume Mabilleau, Stephanie A. Mowery, Michael A. Nauck, Aaron Novikoff, Frank Reimann, Anna G. Roberts, Mette M. Rosenkilde, Ricardo J. Samms, Philip E. Scherer, Randy J. Seeley, Kyle W. Sloop, Christian Wolfrum, Denise Wootten, Richard D. DiMarchi, Matthias H. Tschöp

Source: Molecular Metabolism, Vol 95, Iss , Pp 102118- (2025)

Subject Terms: Diabetes, GLP-1, GIP, Incretin, Insulin, Obesity, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877825000250; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/47fb9d758cf640c696e3da5f4001e25b

Loss of GIPR in LEPR cells impairs glucose control by GIP and GIP:GLP-1 co-agonism without affecting body weight and food intake in mice

Authors: Seun Akindehin, Arkadiusz Liskiewicz, Daniela Liskiewicz, Miriam Bernecker, Cristina Garcia-Caceres, Daniel J. Drucker, Brian Finan, Gerald Grandl, Robert Gutgesell, Susanna M. Hofmann, Ahmed Khalil, Xue Liu, Perla Cota, Mostafa Bakhti, Oliver Czarnecki, Aimée Bastidas-Ponce, Heiko Lickert, Lingru Kang, Gandhari Maity, Aaron Novikoff, Sebastian Parlee, Ekta Pathak, Sonja C. Schriever, Michael Sterr, Siegfried Ussar, Qian Zhang, Richard DiMarchi, Matthias H. Tschöp, Paul T. Pfluger, Jonathan D. Douros, Timo D. Müller

Source: Molecular Metabolism, Vol 83, Iss , Pp 101915- (2024)

Subject Terms: Obesity, Type 2 diabetes, GIP, GLP-1, GIPR:GLP-1R co-agonism, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877824000462; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/4df457ac59ce49e8af09680efdd590e2

TRPM7 kinase is required for insulin production and compensatory islet responses during obesity

Authors: Noushafarin Khajavi, Andreas Beck, Klea Riçku, Philipp Beyerle, Katharina Jacob, Sabrina F. Syamsul, Anouar Belkacemi, Peter S. Reinach, Pascale C.F. Schreier, Houssein Salah, Tanja Popp, Aaron Novikoff, Andreas Breit, Vladimir Chubanov, Timo D. Müller, Susanna Zierler, Thomas Gudermann

Source: JCI Insight, Vol 8, Iss 3 (2023)

Subject Terms: Cell biology, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/2379-3708

Access URL: https://doaj.org/article/3e995b7dace7473fa3fc520fc567dc3c

Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono- and dual-agonists

Authors: Aaron Novikoff, Shannon L. O'Brien, Miriam Bernecker, Gerald Grandl, Maximilian Kleinert, Patrick J. Knerr, Kerstin Stemmer, Martin Klingenspor, Anja Zeigerer, Richard DiMarchi, Matthias H. Tschöp, Brian Finan, Davide Calebiro, Timo D. Müller

Source: Molecular Metabolism, Vol 49, Iss , Pp 101181- (2021)

Subject Terms: GLP-1R, GIPR, Biased agonism, Receptor Internalization, Receptor Trafficking, Dual-agonists, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877821000211; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/3747ffadfcfc4ababd52d92c0564e71b