Neoadjuvant systemic oncolytic vesicular stomatitis virus is safe and may enhance long-term survivorship in dogs with naturally occurring osteosarcoma

Authors: Kelly M. Makielski, Aaron L. Sarver, Michael S. Henson, Kathleen M. Stuebner, Antonella Borgatti, Lukkana Suksanpaisan, Caitlin Preusser, Alexandru-Flaviu Tabaran, Ingrid Cornax, M. Gerard O’Sullivan, Andrea Chehadeh, Donna Groschen, Kelly Bergsrud, Sara Pracht, Amber Winter, Lauren J. Mills, Marc D. Schwabenlander, Melissa Wolfe, Michael A. Farrar, Gary R. Cutter, Joseph S. Koopmeiners, Stephen J. Russell, Jaime F. Modiano, Shruthi Naik

Source: Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100736- (2023)

Subject Terms: oncolytic virus, osteosarcoma, neoadjuvant, immunotherapy, virotherapy, tumor microenvironment, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2372770523000852; https://doaj.org/toc/2372-7705

Access URL: https://doaj.org/article/f4f7cab98bbe4ae5a0cfe31df10cc42c

Increased risk of cancer in dogs and humans: A consequence of recent extension of lifespan beyond evolutionarily determined limitations?

Authors: Aaron L. Sarver, Kelly M. Makielski, Taylor A. DePauw, Ashley J. Schulte, Jaime F. Modiano

Source: Aging and Cancer, Vol 3, Iss 1, Pp 3-19 (2022)

Subject Terms: cancer‐protective mechanisms, cancer risk, evolution, longevity, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282, Geriatrics, RC952-954.6

File Description: electronic resource

Relation: https://doaj.org/toc/2643-8909

Access URL: https://doaj.org/article/c8eaeac0ad9542d5beae4c6db42ceb10

BRAF inhibition in melanoma is associated with the dysregulation of histone methylation and histone methyltransferases

Authors: Florina Grigore, Hana Yang, Nicholas D. Hanson, Matthew W. VanBrocklin, Aaron L. Sarver, James P. Robinson

Source: Neoplasia: An International Journal for Oncology Research, Vol 22, Iss 9, Pp 376-389 (2020)

Subject Terms: BRAF, Histone, Melanoma, Mouse, Resistance, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S1476558620301287; https://doaj.org/toc/1476-5586

Access URL: https://doaj.org/article/d80ae3ffcea34140aa80065f5fa10623

OMCD: OncomiR Cancer Database

Authors: Aaron L. Sarver, Anne E. Sarver, Ce Yuan, Subbaya Subramanian

Source: BMC Cancer, Vol 18, Iss 1, Pp 1-6 (2018)

Subject Terms: Cancer, microRNA, OncomiR, TCGA, Database, miRNA, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: http://link.springer.com/article/10.1186/s12885-018-5085-z; https://doaj.org/toc/1471-2407

Access URL: https://doaj.org/article/618144fbc6cd467aa50ea3a20e58ecc5

Comparative Approach to the Temporo-Spatial Organization of the Tumor Microenvironment

Authors: Kendall L. Langsten, Jong Hyuk Kim, Aaron L. Sarver, Mark Dewhirst, Jaime F. Modiano

Source: Frontiers in Oncology, Vol 9 (2019)

Subject Terms: tumor microenvironment, temporo-spatial organization, dog, canine, human, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fonc.2019.01185/full; https://doaj.org/toc/2234-943X

Access URL: https://doaj.org/article/83c7fcdb323840239594f1192726822b

Risk Factors for Development of Canine and Human Osteosarcoma: A Comparative Review

Authors: Kelly M. Makielski, Lauren J. Mills, Aaron L. Sarver, Michael S. Henson, Logan G. Spector, Shruthi Naik, Jaime F. Modiano

Source: Veterinary Sciences, Vol 6, Iss 2, p 48 (2019)

Subject Terms: bone cancer, osteosarcoma, dog, human, pediatric, comparative oncology, genetics, risk factors, Veterinary medicine, SF600-1100

File Description: electronic resource

Relation: https://www.mdpi.com/2306-7381/6/2/48; https://doaj.org/toc/2306-7381

Access URL: https://doaj.org/article/24664900bc2147789b6a5b27b227695d

Retroviral insertional mutagenesis identifies the del(5q) genes, CXXC5, TIFAB and ETF1, as well as the Wnt pathway, as potential targets in del(5q) myeloid neoplasms

Authors: Angela Stoddart, Zhijian Qian, Anthony A. Fernald, Rachel J. Bergerson, Jianghong Wang, Theodore Karrison, John Anastasi, Elizabeth T. Bartom, Aaron L. Sarver, Megan E. McNerney, David A. Largaespada, Michelle M. Le Beau

Source: Haematologica, Vol 101, Iss 6 (2016)

Subject Terms: Diseases of the blood and blood-forming organs, RC633-647.5

File Description: electronic resource

Relation: https://haematologica.org/article/view/7750; https://doaj.org/toc/0390-6078; https://doaj.org/toc/1592-8721

Access URL: https://doaj.org/article/38894833a35240298034dca589cfe5fb

Genome-wide association study identifies shared risk loci common to two malignancies in golden retrievers.

Authors: Noriko Tonomura, Ingegerd Elvers, Rachael Thomas, Kate Megquier, Jason Turner-Maier, Cedric Howald, Aaron L Sarver, Ross Swofford, Aric M Frantz, Daisuke Ito, Evan Mauceli, Maja Arendt, Hyun Ji Noh, Michele Koltookian, Tara Biagi, Sarah Fryc, Christina Williams, Anne C Avery, Jong-Hyuk Kim, Lisa Barber, Kristine Burgess, Eric S Lander, Elinor K Karlsson, Chieko Azuma, Jaime F Modiano, Matthew Breen, Kerstin Lindblad-Toh

Source: PLoS Genetics, Vol 11, Iss 2, p e1004922 (2015)

Subject Terms: Genetics, QH426-470

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4333733?pdf=render; https://doaj.org/toc/1553-7390; https://doaj.org/toc/1553-7404

Access URL: https://doaj.org/article/5b00e49abada4f5abe8f6eab4d5205b1

Insulin Receptor Substrate Adaptor Proteins Mediate Prognostic Gene Expression Profiles in Breast Cancer.

Authors: Marc A Becker, Yasir H Ibrahim, Annabell S Oh, Dedra H Fagan, Sara A Byron, Aaron L Sarver, Adrian V Lee, Leslie M Shaw, Cheng Fan, Charles M Perou, Douglas Yee

Source: PLoS ONE, Vol 11, Iss 3, p e0150564 (2016)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b3a2a113adc349f9a86de76741740fe5

Genetic signature of histiocytic sarcoma revealed by a sleeping beauty transposon genetic screen in mice.

Authors: Raha A Been, Michael A Linden, Courtney J Hager, Krista J DeCoursin, Juan E Abrahante, Sean R Landman, Michael Steinbach, Aaron L Sarver, David A Largaespada, Timothy K Starr

Source: PLoS ONE, Vol 9, Iss 5, p e97280 (2014)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC4020815?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/fd34e899663546a0b2155c0e9b95ad2e

Combinatorial treatment of DNA and chromatin-modifying drugs cause cell death in human and canine osteosarcoma cell lines.

Authors: Venugopal Thayanithy, ChangWon Park, Aaron L Sarver, Reena V Kartha, Derek M Korpela, Ashley J Graef, Clifford J Steer, Jaime F Modiano, Subbaya Subramanian

Source: PLoS ONE, Vol 7, Iss 9, p e43720 (2012)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: http://europepmc.org/articles/PMC3434163?pdf=render; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/b9d298e242d24dcda4d8522d88044f7f

miRNA expression in colon polyps provides evidence for a multihit model of colon cancer.

Authors: Ann L Oberg, Amy J French, Aaron L Sarver, Subbaya Subramanian, Bruce W Morlan, Shaun M Riska, Pedro M Borralho, Julie M Cunningham, Lisa A Boardman, Liang Wang, Thomas C Smyrk, Yan Asmann, Clifford J Steer, Stephen N Thibodeau

Source: PLoS ONE, Vol 6, Iss 6, p e20465 (2011)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21694772/?tool=EBI; https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/f4d0f3cdd8ea4a0685a81183c254f6b1