Syndecan-1 in the Serum of Deceased Kidney Donors as a Potential Biomarker of Kidney Function

Authors: Navratil, Pavel ^{a, b, ⁎}, Sahi, Sukhdeep ^c, Hruba, Petra ^d, Ticha, Alena ^e, Timkova, Katarina ^f, Viklicky, Ondrej ^f, Cerny, Vladimir ^{b, g, h}, Astapenko, David ^{b, h, i}

Source: In Transplantation Proceedings March 2025 57(2):187-193

Low-grade hemodilution improves the microcirculatory function in surgical patients

Authors: Hahn, Robert G. ^{a, ⁎}, Tlapakova, Katerina ^b, Koudelova, Hana ^b, Knoblochova, Veronika ^c, Rehak, David ^d, Cerny, Vladimir ^{d, e, f, g, h}, Astapenko, David ^{b, d, e}

Source: In Microvascular Research March 2025 158

Impact of anesthetics on rat hippocampus and neocortex: A comprehensive proteomic study based on label-free mass spectrometry

Authors: Astapenko, David ^{a, b}, Vajrychova, Marie ^{c, ⁎}, Fabrik, Ivo ^c, Kupcik, Rudolf ^c, Pimkova, Kristyna ^{c, e}, Tambor, Vojtech ^c, Radochova, Vera ^d, Cerny, Vladimir ^{a, f}

Source: In Heliyon 30 March 2024 10(6)

Lipid emulsions prevent postoperative abdominal adhesions

Authors: Sirovy, Miroslav, Krupova, Marketa, Hyspler, Radomir, Ticha, Alena, Kolackova, Martina, Andrys, Ctirad, Radochova, Vera, Astapenko, David, Odlozilová, Sarka, Kotek, Jirí, Zajak, Jan, Paral, Jiri

Source: Asian journal of surgery. 46(1):465-471

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100178319068.0x000001&indx=1&recIds=ETOCvdc_100178319068.0x000001

Exogenous surfactant for lung contusion causing ARDS: A systematic review of clinical and experimental reports.

Authors: Merkl, Tomáš^1,2,3 (AUTHOR) tomas.merkl@fnhk.cz, Astapenko, David^4,5 (AUTHOR), Štichhauer, Radek^2,3 (AUTHOR), Šafus, Antonín^2,3 (AUTHOR), Dušek, Tomáš^1,3,6 (AUTHOR), Kotek, Jiří^1,6 (AUTHOR), Řehák, David³ (AUTHOR), Lochman, Petr^1,3,6 (AUTHOR)

Source: Clinical Respiratory Journal. May2024, Vol. 18 Issue 5, p1-7. 7p.

Subject Terms: *MECONIUM aspiration syndrome, *PULMONARY surfactant, *OXYGENATORS, *ADULT respiratory distress syndrome, *SURFACE active agents, *BRONCHI

Modulation of the capillary leakage by exogenous albumin in a rat model of endothelial glycocalyx damage.

Authors: Astapenko, David^1,2,3 (AUTHOR) astapenko.d@seznam.cz, Zrzavecky, Marek² (AUTHOR), Gorskaja, Diana² (AUTHOR), Hyspler, Radomir^2,4 (AUTHOR), Ticha, Alena⁴ (AUTHOR), Radochova, Vera⁵ (AUTHOR), Lehmann, Christian^6,7,8,9 (AUTHOR), Malbrain, Manu L.N.G.^10,11,12 (AUTHOR), Cerny, Vladimir^1,2,3,13,14 (AUTHOR), Hahn, Robert G.¹⁵ (AUTHOR)

Source: Clinical Hemorheology & Microcirculation. 2024, Vol. 86 Issue 4, p509-517. 9p.

Subject Terms: *ALBUMINS, *GLYCOCALYX, *BLOOD proteins, *LEAKAGE, *ANIMAL disease models

A novel "lateral approach short axis in-plane" technique vs. conventional "short-axis out-of-plane approach" for ultrasound-guided internal jugular vein access: a prospective randomized non-inferiority trial.

Authors: Kalina, Michal, Vargová, Patricia, Bubeníková, Adéla, Škulec, Roman, Černý, Vladimír, Astapenko, David

Source: Ultrasound Journal; 1/16/2025, Vol. 17 Issue 1, p1-8, 8p

Subject Terms: JUGULAR vein, MEDICAL sciences, CRITICALLY ill, POINT-of-care testing, CATHETERIZATION

Protection of the endothelium and endothelial glycocalyx by hydrogen against ischaemia-reperfusion injury in a porcine model of cardiac arrest.

Authors: Astapenko, David^1,2,3 (AUTHOR) astapenko.d@seznam.cz, Hyspler, Radomir^2,4 (AUTHOR), Ticha, Alena⁴ (AUTHOR), Tomasova, Adela^2,4 (AUTHOR), Navratil, Pavel^2,5 (AUTHOR), Zrzavecky, Marek² (AUTHOR), Byreddy, Bhavya² (AUTHOR), Sedlacek, Petr² (AUTHOR), Radochova, Vera⁶ (AUTHOR), Skulec, Roman^1,2,7,8,9 (AUTHOR), Hahn, Robert G.¹⁰ (AUTHOR), Lehmann, Christian^11,12,13,14 (AUTHOR), Malbrain, Manu L.N.G.^15,16,17 (AUTHOR), Cerny, Vladimir^{1,2,3,7,8,11,18,19,20} (AUTHOR)

Source: Clinical Hemorheology & Microcirculation. 2023, Vol. 85 Issue 2, p135-146. 12p.

Subject Terms: *RETURN of spontaneous circulation, *CARDIAC arrest, *GLYCOCALYX, *VENTRICULAR fibrillation, *ENDOTHELIUM

The Effect of Fluid Loading and Hypertonic Saline Solution on Cortical Cerebral Microcirculation and Glycocalyx Integrity

Authors: Dostalova, Vlasta, Astapenko, David, Kraus, Jaroslav, Cerny, Vladimir, Ticha, Alena, Hyspler, Radomir, Radochova, Vera, Paral, Jiri, Dostal, Pavel

Source: Journal of neurosurgical anesthesiology. 31(4):434-443

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100088462238.0x000001&indx=1&recIds=ETOCvdc_100088462238.0x000001

Endothelial glycocalyx damage in patients with severe COVID-19 on mechanical ventilation – A prospective observational pilot study.

Authors: Astapenko, David^1,2,3 (AUTHOR) Astapenko.D@seznam.cz, Tomasova, Adela^2,4 (AUTHOR), Ticha, Alena⁴ (AUTHOR), Hyspler, Radomir^2,4 (AUTHOR), Chua, Huey Shin² (AUTHOR), Manzoor, Mubashar² (AUTHOR), Skulec, Roman^2,5 (AUTHOR), Lehmann, Christian^6,7,8,9 (AUTHOR), Hahn, Robert G.^10,11 (AUTHOR), Malbrain, Manu LNG^12,13 (AUTHOR), Cerny, Vladimir^1,2,3,5,6 (AUTHOR)

Source: Clinical Hemorheology & Microcirculation. 2022, Vol. 81 Issue 3, p205-219. 15p.

Subject Terms: *COVID-19, *GLYCOCALYX, *ARTIFICIAL respiration, *SEPTIC shock, *INTENSIVE care units

A porcine model of endothelial glycocalyx damage by enzymatic digestion: A pilot study.

Authors: Astapenko, David^1,2 (AUTHOR) Astapenko.D@seznam.cz, Ticha, Alena³ (AUTHOR), Hyspler, Radomir^2,3 (AUTHOR), Tomasova, Adela³ (AUTHOR), Navratil, Pavel^2,4 (AUTHOR), Maly, Ondrej^2,5,6 (AUTHOR), Parizkova, Renata Cerna^1,2 (AUTHOR), Cizkova, Dana⁷ (AUTHOR), Huey, Shin Chua² (AUTHOR), Lehmann, Christian⁸ (AUTHOR), Malbrain, Manu L.N.G.^9,10 (AUTHOR), Cerny, Vladimir^1,2,8,11,12 (AUTHOR)

Source: Clinical Hemorheology & Microcirculation. 2021, Vol. 78 Issue 3, p325-338. 14p.

Subject Terms: *DAMAGE models, *GLYCOCALYX, *DIGESTION, *HEPARANASE, *HYALURONIDASES

Targeting the endothelial glycocalyx in acute critical illness as a challenge for clinical and laboratory medicine

Authors: Cerny, Vladimir, Astapenko, David, Brettner, Florian, Benes, Jan, Hyspler, Radomir, Lehmann, Christian, Zadak, Zdenek

Source: Critical reviews in clinical laboratory sciences. 54(5):343-357

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100105417192.0x000001&indx=1&recIds=ETOCvdc_100105417192.0x000001

Evaluation of endothelial glycocalyx in healthy volunteers – An observational study.

Authors: Astapenko, David^1,2,3 (AUTHOR) Astapenko.d@seznam.cz, Ticha, Alena^3,4 (AUTHOR), Tomasova, Adela⁴ (AUTHOR), Hyspler, Radomir^2,3,4 (AUTHOR), Zadak, Zdenek^2,3 (AUTHOR), Lehmann, Christian^5,6,7,8 (AUTHOR), Cerny, Vladimir^1,2,3,5,9 (AUTHOR)

Source: Clinical Hemorheology & Microcirculation. 2020, Vol. 75 Issue 3, p257-265. 9p.

Subject Terms: *GLYCOCALYX, *VOLUNTEERS, *TISSUE metabolism, *SCIENTIFIC observation, *YOUNG adults

Clinical physiology aspects of chloremia in fluid therapy: a systematic review

Authors: Astapenko, David [and others]

Source: Perioperative medicine. 9(1)

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100190468014.0x000001&indx=1&recIds=ETOCvdc_100190468014.0x000001

Pyelovesicostomy as an Alternative Surgical Treatment for Complex Ureteral Lesions After Kidney Transplant.

Authors: Navratil, Pavel, Sahi, Sukhdeep, Spacek, Jiri, Pacovsky, Jaroslav, Lesko, Michal, Gunka, Igor, Astapenko, David

Source: Experimental & Clinical Transplantation; Sep2023, Vol. 21 Issue 9, p712-716, 5p

Endothelial glycocalyx in acute care surgery – what anaesthesiologists need to know for clinical practice.

Authors: Astapenko, David^1,2,3, Benes, Jan^4,5,6, Pouska, Jiri^4,5, Lehmann, Christian^7,8,9,10,11, Islam, Sufia¹², Cerny, Vladimir^1,2,3,7,13 cernyvla1960@mail.com

Source: BMC Anesthesiology. 12/20/2019, Vol. 19 Issue 1, p1-13. 13p.

Subject Terms: *ANESTHESIOLOGISTS, *BLOOD transfusion, *CATASTROPHIC illness, *CELL membranes, *CONVALESCENCE, *CRITICAL care medicine, *EMERGENCY medical services, *EPITHELIAL cells, *FLUID therapy, *HEMORRHAGIC shock, *HYDROCORTISONE, *INFLAMMATION, *MEDICAL practice, *PATIENTS, *PROFESSIONS, *SERUM albumin, *SURGICAL complications, *SYSTEMATIC reviews, *OXIDATIVE stress, *TREATMENT effectiveness, *SEVERITY of illness index, *SEVOFLURANE, *DISEASE complications

Effect of short-term administration of lipid emulsion on endothelial glycocalyx integrity in ICU patients – A microvascular and biochemical pilot study.

Authors: Astapenko, David^1,2 (AUTHOR), Turek, Zdenek¹ (AUTHOR), Dostal, Pavel¹ (AUTHOR), Hyspler, Radomir^2,3 (AUTHOR), Ticha, Alena^2,3 (AUTHOR), Kaska, Milan⁴ (AUTHOR), Zadak, Zdenek² (AUTHOR), Skulec, Roman⁵ (AUTHOR), Lehmann, Christian⁶ (AUTHOR), Cerny, Vladimir^1,2,5,6 (AUTHOR) cernyvla1960@gmail.com

Source: Clinical Hemorheology & Microcirculation. 2019, Vol. 73 Issue 2, p329-339. 11p.

Subject Terms: *ERYTHROCYTES, *LIPIDS, *EMULSIONS, *PILOT projects, *SYNDECANS

Company/Entity: UNIVERSITY of Colorado Hospital

Effect of acute hypernatremia induced by hypertonic saline administration on endothelial glycocalyx in rabbits.

Authors: Astapenko, David¹ (AUTHOR), Dostalova, Vlasta¹ (AUTHOR), Kraus, Jaroslav¹ (AUTHOR), Radochova, Vera² (AUTHOR), Dostal, Pavel¹ (AUTHOR), Ticha, Alena³ (AUTHOR), Hyspler, Radomir³ (AUTHOR), Lehmann, Christian^4,5 (AUTHOR), Cerny, Vladimir^1,4,6,7 (AUTHOR) cernyvla1960@gmail.com

Source: Clinical Hemorheology & Microcirculation. 2019, Vol. 72 Issue 1, p107-116. 10p.

Subject Terms: *HYPERNATREMIA, *GLYCOCALYX, *ERYTHROCYTES, *RABBITS, *INTRAVENOUS therapy

Neuraxial anesthesia is less harmful to the endothelial glycocalyx during elective joint surgery compared to general anesthesia.

Authors: Astapenko, David¹ (AUTHOR) Astapenko.d@seznam.cz, Pouska, Jiri² (AUTHOR), Benes, Jan² (AUTHOR), Skulec, Roman^3,4 (AUTHOR), Lehmann, Christian^5,6,7,8,9 (AUTHOR), Vink, Hans¹⁰ (AUTHOR), Cerny, Vladimir^1,3,4,5 (AUTHOR)

Source: Clinical Hemorheology & Microcirculation. 2019, Vol. 72 Issue 1, p11-21. 11p.

Subject Terms: *GLYCOCALYX, *TOTAL knee replacement, *GENERAL anesthesia, *KNEE surgery, *ANESTHESIA, *ELECTIVE surgery

The modulation of endothelial glycocalyx by sulodexide on the porcine model of enzymatic endothelial glycocalyx damage – a pilot study.

Authors: Astapenko, David^1,2,3 (AUTHOR) astapenko.d@seznam.cz, Gorskaja, Diana⁴ (AUTHOR), Zrzavecky, Marek⁵ (AUTHOR), Kawashima, Hanako² (AUTHOR), Ssali, Edward² (AUTHOR), Navratil, Pavel^2,6 (AUTHOR), Hana, Ludek^7,8 (AUTHOR), Motesicky, Jan⁹ (AUTHOR), Radochova, Vera¹⁰ (AUTHOR), Hyspler, Radomir^2,11 (AUTHOR), Ticha, Alena¹¹ (AUTHOR), Lehmann, Christian^12,13,14,15 (AUTHOR), Malbrain, Manu LNG^16,17,18 (AUTHOR), Zadak, Zdenek¹¹ (AUTHOR), Cerny, Vladimir^1,2,3,19 (AUTHOR)

Source: Clinical Hemorheology & Microcirculation. Feb2025, p1.

Subject Terms: *HEPARANASE, *SYNDECANS, *GLYCOCALYX, *HYALURONIDASES, *ONE-way analysis of variance