Andrographolide Sulfonates and Xiyanping: A Review of Chemical Composition, Pharmacological Activities, Clinical Applications, and Adverse Reactions.

Authors: Li, Zihong^1,2 (AUTHOR), Yao, Lihao¹ (AUTHOR), Liu, Zhenjie^1,2 (AUTHOR), Wang, Liuping^1,2 (AUTHOR), Ruan, Huini^1,2 (AUTHOR), Shen, Yuanle^1,2 (AUTHOR), Zhang, Peng^1,2 (AUTHOR), Li, Kaitong^1,2 (AUTHOR), Wang, Honglan^1,2 (AUTHOR), Fan, Lili¹ (AUTHOR) fengjianfang@vip.163.com, Tu, Liangxing³ (AUTHOR) tufrankie@163.com, Feng, Jianfang² (AUTHOR) tufrankie@163.com

Source: Pharmaceuticals (14248247). Feb2025, Vol. 18 Issue 2, p183. 19p.

Subject Terms: *ANDROGRAPHIS paniculata, *COVID-19 pandemic, *CLINICAL medicine, *RESPIRATORY infections, *ACANTHACEAE

Genome-Wide Identification of CONSTANS - like (COL) Gene Family and the Potential Function of ApCOL08 Under Salt Stress in Andrographis paniculata.

Authors: Zhao, Yizhu¹ (AUTHOR) 15868190169@163.com, Xu, Jiahao¹ (AUTHOR), Xu, Xinyi¹ (AUTHOR), Liu, Hui² (AUTHOR), Chang, Qinxiang¹ (AUTHOR), Xu, Ling¹ (AUTHOR) lxu@zstu.edu.cn, Liang, Zongsuo¹ (AUTHOR) lxu@zstu.edu.cn

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 2, p724. 25p.

Subject Terms: *ANDROGRAPHIS paniculata, *SESAME, *CHROMOSOME duplication, *FLOWERING of plants, *GENE families

An Innovative Method of Improving an Extract of Andrographis paniculata from Leaves: Its Anticancer Effect Involves the Cell Endoplasmic Reticulum.

Authors: Maiuolo, Jessica¹ (AUTHOR) maiuolo@unicz.it, Caminiti, Rosamaria¹ (AUTHOR) r.caminiti@unicz.it, Mazza, Valeria¹ (AUTHOR) valeria.mazza@unicz.it, Oppedisano, Francesca¹ (AUTHOR) oppedisanof@libero.it, Nucera, Saverio¹ (AUTHOR) maria.serra@studenti.unicz.it, Serra, Maria¹ (AUTHOR) robertamacri85@gmail.com, Macrì, Roberta¹ (AUTHOR) palma@unicz.it, Palma, Ernesto¹ (AUTHOR) mollace@libero.it, Eng, Annie² (AUTHOR) annie@hpingredients.com, Mollace, Vincenzo¹ (AUTHOR) muscoli@unicz.it, Muscoli, Carolina¹ (AUTHOR)

Source: International Journal of Molecular Sciences. Jan2025, Vol. 26 Issue 1, p344. 18p.

Subject Terms: *ANDROGRAPHIS paniculata, *POISONS, *ANNEXINS, *CELL survival, *ANTINEOPLASTIC agents

Andrographis paniculata (Burm. f.) Nees extract ameliorates insulin resistance in the insulin-resistant HepG2 cells via GLUT2/IRS-1 pathway.

Authors: Ningsih, Sri¹ (AUTHOR) Srin002@brin.go.id, Kusumastuti, Siska Andrina¹ (AUTHOR), Nuralih, Nuralih¹ (AUTHOR), Fajriawan, Adam Arditya¹ (AUTHOR), Permatasari, Devi¹ (AUTHOR), Yunianto, Prasetyawan¹ (AUTHOR), Ramadhan, Donny¹ (AUTHOR), Wulandari, Mayriska Tri² (AUTHOR), Firdausi, Nisrina¹ (AUTHOR), Nurhadi, Nurhadi¹ (AUTHOR), Giarni, Reni² (AUTHOR), Agustini, Kurnia¹ (AUTHOR), Wibowo, Agung Eru¹ (AUTHOR), Rosidah, Idah¹ (AUTHOR), Rengganis, Tiya Novlita¹ (AUTHOR), Ngatinem, Ngatinem¹ (AUTHOR), Subiantoro, Agus Himawan¹ (AUTHOR), Supriyono, Agus¹ (AUTHOR)

Source: Archives of Physiology & Biochemistry. Dec2024, Vol. 130 Issue 6, p779-789. 11p.

Subject Terms: *ANDROGRAPHIS paniculata, *INSULIN sensitivity, *INSULIN resistance, *INSULIN receptors, *GLUCOSE transporters

In vitro Antioxidant Potential of Andrographis paniculata Extracts.

Authors: Chukwu, Onyeneke Eusebius¹ oluwaropoboluwade2019@gmail.com, Oluwaropo, Boluwade¹, Omozuwa, Victor¹, Onwe, Chibuike A.¹, Martins Omorogie, Olowoyo¹, Onwordi, Emmanuel¹

Source: Systematic Reviews in Pharmacy. Dec2024/Jan2025, Vol. 15 Issue 12, p373-376. 4p.

Subject Terms: *ANDROGRAPHIS paniculata, *TREATMENT effectiveness, *OXIDANT status, *HYPERTENSION, *CARBONATED beverages

In vitro anthelmintic activity of Phyllanthus niruri Linn., Andrographis paniculata, Curcuma xanthorrhiza Roxb., and Curcuma aeruginosa Roxb. ethanol extracts on the motility and cuticle damage of Ascaridia galli.

Authors: Tiuria, Risa¹ risati@apps.ipb.ac.id, Sutardi, Lina Noviyanti² linans@apps.ipb.ac.id, Nugraha, Arifin Budiman¹ arifin@apps.ipb.ac.id, Subangkit, Mawar³ bangkit@apps.ipb.ac.id

Source: Veterinary World. Nov2024, Vol. 17 Issue 11, p2488-2496. 9p.

Subject Terms: *ANDROGRAPHIS paniculata, *PLANT extracts, *ALIMENTARY canal, *SALT, *CUTICLE

Genome-Wide Identification and Characterization of Diterpenoid Pathway CYPs in Andrographis paniculata and Analysis of Their Expression Patterns under Low Temperature Stress.

Authors: Sun, Mingyang^1,2 (AUTHOR) sunmingyangphy@163.com, Li, Jingyu^1,2 (AUTHOR) jingyuli138@gmail.com, Xu, Shiqiang^1,2 (AUTHOR) shiqxu0376@163.com, Gu, Yan^1,2 (AUTHOR) guyan@gdaas.cn, Wang, Jihua^1,2 (AUTHOR) wangjihua@gdaas.cn

Source: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 19, p10741. 17p.

Subject Terms: *ANDROGRAPHIS paniculata, *MEMBRANE proteins, *CYTOCHROME P-450, *LOW temperatures, *ABIOTIC stress, *GIBBERELLINS

Potential of Medicinal Plants to Inhibit Neurodegenerative Activities in Diabetes: A Systematic Review.

Authors: Phaik Har Yong¹, Wong Xue Yi¹, Meram Azzani² dr_memeazzani@yahoo.com, Guad, Rhanye Mac^3,4, Zhi Xiang Ng⁵

Source: Journal of Young Pharmacists. Oct-Dec2024, Vol. 16 Issue 4, p620-632. 13p.

Subject Terms: *ANDROGRAPHIS paniculata, *PAPAYA, *MEDICINAL plants, *BLOOD sugar, *ACETYLCHOLINESTERASE

Effect of Colchicine on Andrographis Variety Phichit 4-4 for Plant Breeding in Stem and Leaf Characteristics.

Authors: Surson, Suntaree¹ sun_dawn990@hotmail.com, Sitthaphanit, Suphasit², Wongkerson, Khumpanat³

Source: Indian Journal of Agricultural Research. Oct2024, Vol. 58 Issue 5, p744-751. 8p.

Subject Terms: *ANDROGRAPHIS paniculata, *PLANT breeding, *AGRICULTURE, *PLANT stems, *FLOW cytometry

Terminalia bellirica and Andrographis paniculata dietary supplementation in mitigating heat stress-induced behavioral, metabolic and genetic alterations in broiler chickens.

Authors: Fayed, Rabie H.¹ (AUTHOR), Ali, Sara E.² (AUTHOR), Yassin, Aya M.³ (AUTHOR) ayamohye@cu.edu.eg, Madian, K.⁴ (AUTHOR), Bawish, Basma M.¹ (AUTHOR)

Source: BMC Veterinary Research. 9/3/2024, Issue 1, p1-23. 23p.

Subject Terms: *ANDROGRAPHIS paniculata, *LEUKOCYTES, *KIDNEY function tests, *DRINKING behavior, *BROILER chickens, *CHICKS, *POULTRY growth, *FEED additives

Sambiloto leaves (Andrographis paniculata (Burm.f.) Wall. Ex. Nees) nanoemulsion preparations: Optimization of Tween 80 and PEG-400 concentrations as photoprotective agents.

Authors: HARDESTYARIKI, Dwi¹, AL-RASYID, Rida Seranita², APRIANI, Elsa Fitria² elsafitria@mipa.unsri.ac.id

Source: Journal of Research in Pharmacy. 2024, Vol. 28 Issue 5, p1435-1448. 14p.

Subject Terms: *ANDROGRAPHIS paniculata, *FACTORIAL experiment designs, *PRETEENS, *QUERCETIN, *VISCOSITY

In-silico study unveils potential phytocompounds in Andrographis paniculata against E6 protein of the high-risk HPV-16 subtype for cervical cancer therapy.

Authors: Islam, Md. Aminul¹ (AUTHOR) aminul@pahmc.edu.bd, Hossain, Md. Shohel² (AUTHOR), Hasnat, Soharth³ (AUTHOR), Shuvo, Mahmudul Hasan⁴ (AUTHOR), Akter, Shilpy⁵ (AUTHOR), Maria, Mustary Anjum⁴ (AUTHOR), Tahcin, Anika⁴ (AUTHOR), Hossain, Md. Arju⁶ (AUTHOR), Hoque, M. Nazmul³ (AUTHOR) nazmul90@bsmrau.edu.bd

Source: Scientific Reports. 7/26/2024, Vol. 14 Issue 1, p1-18. 18p.

Subject Terms: *ANDROGRAPHIS paniculata, *CERVICAL cancer, *CANCER treatment, *HUMAN papillomavirus, *ROOT-mean-squares

Synthetic Modifications of Andrographolide Targeting New Potential Anticancer Drug Candidates: A Comprehensive Overview.

Authors: Messire, Gatien¹ (AUTHOR) gatien.messire@univ-orleans.fr, Rollin, Patrick¹ (AUTHOR), Gillaizeau, Isabelle¹ (AUTHOR), Berteina-Raboin, Sabine¹ (AUTHOR) sabine.berteina-raboin@univ-orleans.fr

Source: Molecules. Jun2024, Vol. 29 Issue 12, p2884. 21p.

Subject Terms: *ANDROGRAPHIS paniculata, *ANTINEOPLASTIC agents, *SYNTHETIC biology, *CELL lines, *COMMERCIAL product testing, *CANCER cells

Overexpression of 3-hydroxy-3-methylglutaryl coenzyme-A reductase-1 (HMGR1) enhanced andrographolide accumulation in Andrographis paniculata (Burm.F.).

Authors: Marwani, Erly¹ erly@itb.ac.id, Menra, Juane Plantika, Nadhira, Amanda, Kristianti, Tati², Febrianti, Karlina, Dwivany, Fenny Martha

Source: Jordan Journal of Biological Sciences. Jun2024, Vol. 17 Issue 2, p235-246. 12p.

Subject Terms: *ANDROGRAPHIS paniculata, *GENETIC overexpression, *HIGH performance liquid chromatography, *TRANSGENIC plants, *REGENERATION (Botany)

Preparation of Andrographis Paniculata and Rosa Formulation and its Antibacterial Activity Against Urinary Tract Infection Causing Pathogens.

Authors: Thiraviarajan, Akash¹, Shanmugam, Rajeshkumar¹ rajeshkumars.sdc@saveetha.com, Munusamy, Tharani¹

Source: Journal of Pharmacy & Bioallied Sciences. 2024 Supplement, Vol. 16, pS1360-S1364. 5p.

Subject Terms: *ANDROGRAPHIS paniculata, *ANTIBACTERIAL agents, *USEFUL plants, *CITRUS fruits, *ENTEROCOCCUS faecalis, *URINARY tract infections

Geographic Terms: SRI Lanka

Anti-Inflammatory Effect of Herbal Mouthwash Prepared Using Andrographis Paniculata and Rosa Formulation.

Authors: P., Aishvarya Rukmani¹, Shanmugam, Rajeshkumar¹ rajeshkumars.sdc@saveetha.com, Manigandan, Pradeep¹

Source: Journal of Pharmacy & Bioallied Sciences. 2024 Supplement, Vol. 16, pS1345-S1349. 5p.

Subject Terms: *ANDROGRAPHIS paniculata, *DENATURATION of proteins, *MOUTHWASHES, *ANTI-inflammatory agents, *ALBUMINS, *ROSACEAE

Exploitation of Selected Fungal Endophytes of Andrographis paniculata (Burm. f.) Wall. ex Nees for the Production and Optimisation of Tannase and Screening for their Associated Hydrolysing Enzymes; Amylase, Protease, Lipase, and Laccase.

Authors: Mishra, Bibartan^1,2, Santra, Hiran Kanti², Banerjee, Debdulal^1,2 db@mail.vidyasagar.ac.in

Source: Journal of Pure & Applied Microbiology. 2024, Vol. 18 Issue 1, p555-567. 13p.

Subject Terms: *ENDOPHYTIC fungi, *ANDROGRAPHIS paniculata, *LIPASES, *AMYLASES, *FUNGAL enzymes, *ENZYMES, *LACCASE

Geographic Terms: INDIA

Estimation of Andrographolide and Antioxidant Activities in Andrographis peniculata Commercial Products by Color Parameters.

Authors: Petchpoung, Krittaya¹ rdikyp@ku.ac.th, Soiklom, Siriwan¹, Siri-Anusornsak, Wipada¹

Source: Trends in Sciences. Mar2024, Vol. 21 Issue 3, p1-7. 7p.

Subject Terms: *ANDROGRAPHIS paniculata, *ANTIOXIDANTS, *COLORS, *FREE radical scavengers, *COLOR, *HERBAL medicine

Development and Optimization of Andrographis paniculata Extract-Loaded Self-Microemulsifying Drug Delivery System Using Experimental Design Model.

Authors: Pornpitchanarong, Chaiyakarn¹ (AUTHOR) pornpitchanaron_c@su.ac.th, Akkaramongkolporn, Prasert¹ (AUTHOR), Nattapulwat, Nattawat¹ (AUTHOR), Opanasopit, Praneet¹ (AUTHOR), Patrojanasophon, Prasopchai¹ (AUTHOR) patrojanasophon_p@su.ac.th

Source: Pharmaceutics. Feb2024, Vol. 16 Issue 2, p166. 17p.

Subject Terms: *ANDROGRAPHIS paniculata, *DRUG delivery systems, *MICROEMULSIONS, *EXPERIMENTAL design, *ZETA potential, *OLEIC acid, *MEMBRANE permeability (Biology)

Impact of water deficit stress on physiological performance, secondary metabolites, and gene expression in Andrographis paniculata.

Authors: Singh, Pritee¹ (AUTHOR) pritee.siingh@gmail.com, Laxman, R.H.¹ (AUTHOR), Rao, V. Keshava¹ (AUTHOR), Ravishankar, K.V.¹ (AUTHOR), Shivashankara, K.S.¹ (AUTHOR), Kumar, Prakash¹ (AUTHOR)

Source: South African Journal of Botany. Mar2025, Vol. 178, p400-410. 11p.

Subject Terms: *ANDROGRAPHIS paniculata, *METABOLITES, *GENE expression, *PHOTOSYNTHETIC rates, *PHYSIOLOGICAL stress, *CHLOROPHYLL spectra