Research Progress on the Impact and Mechanism of Energy Metabolism-Related Signaling Pathways in Postmortem Muscle on Meat Tenderness

Authors: AN Yufan, MAO Yanwei, YANG Xiaoyin, ZHU Lixian, LI Jiqiang, HAO Jiangang, GU Yue, CHENG Haijian, ZHANG Yimin

Source: Shipin Kexue, Vol 46, Iss 5, Pp 310-318 (2025)

Subject Terms: energy metabolism, glycolysis, amp-activated protein kinase, sirtuin 1, endogenous protease system, tenderness, Food processing and manufacture, TP368-456

File Description: electronic resource

Relation: https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-5-033.pdf; https://doaj.org/toc/1002-6630

Access URL: https://doaj.org/article/df5917150c3145eabc7505e64e497f88

Neuroprotective Role of Transchalcone in Parkinson‘s Disease through AMP-activated Protein Kinase-mediated Signaling Pathway

Authors: Yao Cheng, Shaik Althaf Hussain, Turki Mayudh Alrubie, Xiaomin Zhang

Source: Journal of Physiological Investigation, Vol 67, Iss 6, Pp 312-320 (2024)

Subject Terms: amp-activated protein kinase, cytokines, mitochondria, neuroprotection, parkinson’s disease, trans-chalcone, Physiology, QP1-981, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://journals.lww.com/cjop/fulltext/2024/67060/neuroprotective_role_of_transchalcone_in.3.aspx; https://doaj.org/toc/2950-6344; https://doaj.org/toc/2950-6352

Access URL: https://doaj.org/article/2101876adaa342cd8ac09be66075bda5

ANXA1-FPR2 axis mitigates the susceptibility to atrial fibrillation in obesity via rescuing AMPK activity in response to lipid overload

Authors: Peng Liu, Lu Wang, Yixin Wang, Linyan Jin, Haoyu Gong, Jiali Fan, Yudi Zhang, Haiquan Li, Bowen Fu, Qiaozhu Wang, Yuping Fu, Boyuan Fan, Xiaoli Li, Hongtao Wang, Xinghua Qin, Qiangsun Zheng

Source: Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-21 (2024)

Subject Terms: Atrial fibrillation, Obesity, ANXA1-FPR2, AMP-activated protein kinase, Lipotoxicity, Diseases of the circulatory (Cardiovascular) system, RC666-701

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2840

Access URL: https://doaj.org/article/96c73b61748f4364aea9638d05e197f2

The AMPK-SIRT1 Axis: Redefining type 2 diabetes mellitus management

Authors: Mighty Kemelo, Phillip Moseki

Source: Results in Chemistry, Vol 14, Iss , Pp 102139- (2025)

Subject Terms: Type 2 diabetes mellitus (T2DM), Natural polyphenols, AMP-activated protein kinase (AMPK), Oral hypoglycemic drugs, Sirtuin-1 (SIRT1), Sirtuin-activating compounds (STACs), Chemistry, QD1-999

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211715625001225; https://doaj.org/toc/2211-7156

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Metformin-mediated intestinal AMPK activation ameliorates PCOS through gut microbiota modulation and metabolic pathways

Authors: Yating Xu, Li Ning, Yu Si, Xiu Li, Ruyue Wang, Qingling Ren

Source: Frontiers in Endocrinology, Vol 16 (2025)

Subject Terms: polycystic ovary syndrome, AMP-activated protein kinase, Indole-3-carboxaldehyde, gut microbiota, serum metabolites, Diseases of the endocrine glands. Clinical endocrinology, RC648-665

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fendo.2025.1526109/full; https://doaj.org/toc/1664-2392

Access URL: https://doaj.org/article/17f8bfb2408d4690963ace982cbd344c

Strategy for treating MAFLD: Electroacupuncture alleviates hepatic steatosis and fibrosis by enhancing AMPK mediated glycolipid metabolism and autophagy in T2DM rats

Authors: Haoru Duan, Shanshan Song, Rui Li, Suqin Hu, Shuting Zhuang, Shaoyang liu, Xiaolu Li, Wei Gao

Source: Diabetology & Metabolic Syndrome, Vol 16, Iss 1, Pp 1-16 (2024)

Subject Terms: Type 2 diabetes, Metabolic dysfunction-associated fatty liver disease, Electroacupuncture, AMP-activated protein kinase signaling pathway, Autophagy, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1758-5996

Access URL: https://doaj.org/article/2c71a1e19f9046978fd65d0c0056e5ab

Extract of Phyllanthus emblica L. fruit stimulates basal glucose uptake and ameliorates palmitate-induced insulin resistance through AMPK activation in C2C12 myotubes

Authors: Hai-yan Li, Chun-fei Li, Chun-hui Liu, Sun-ce Chen, Yi-fan Liu, Quan-he Lv, Wen Zhang

Source: BMC Complementary Medicine and Therapies, Vol 24, Iss 1, Pp 1-14 (2024)

Subject Terms: Phyllanthus emblica L., Glucose uptake, AMP-activated protein kinase, Insulin sensitivity, C2C12 myotubes, Palmitate, Other systems of medicine, RZ201-999

File Description: electronic resource

Relation: https://doaj.org/toc/2662-7671

Access URL: https://doaj.org/article/e6277b61b6534e37ab220c0abdd89ddb

A novel pyridine-2-one AMPK inhibitor: Discovery, mechanism, and in vivo evaluation in a hypoxic pulmonary arterial hypertension rat model

Authors: Tan, Wenhua ^{a, c, d, 1}, Wang, Yu ^{a, c, d, 1}, Li, Mengqi ^{a, c, d}, Zhao, Congke ^{a, c, d}, Hu, Yuanbo ^{a, c, d}, Gao, Ruizhe ^b, Chen, Zhuo ^{a, c, d}, Hu, Liqing ^{b, ⁎⁎}, Li, Qianbin ^{a, c, d, ⁎}

Source: In European Journal of Medicinal Chemistry 15 March 2025 286

Combined deletion of cytosolic 5′-nucleotidases IA and II lowers glycemia by improving skeletal muscle insulin action and lowering hepatic glucose production

Authors: Jacobs, Roxane ¹, Herinckx, Gaëtan ¹, Galland, Noémie ², Balty, Clémence ¹, Vertommen, Didier ¹, Rider, Mark H. ¹, Johanns, Manuel ^{1, ∗}

Source: In Journal of Biological Chemistry March 2025 301(3)

Long-term glucosamine supplementation aggravates atrial fibrillation susceptibility by impairing AMPK signaling

Authors: Qin, Xinghua ^{a, ⁎, 1}, Gong, Haoyu ^{b, 1}, Jin, Lingyan ^b, Wang, Yixin ^b, Dang, Kai ^a, Li, Hui ^c, Zheng, Qiangsun ^{b, ⁎⁎}

Source: In Life Sciences 1 February 2025 362

1-phenyl-3-methyl-5-pyrazolone activates the AMPK pathway to alleviate western-diet induced metabolic dysfunction-associated steatohepatitis in mice

Authors: Chen, Xiaoning ^{a, b, c, d, 1}, Huang, Jiaofeng ^{b, c, d, 1}, You, Yanying ^{b, c, d}, Xue, Hanxin ^{b, c, d}, Wu, Lisha ^{b, c, d}, Zeng, Danyi ^{b, c, d}, Xing, Qingqing ^{b, c, d}, Wu, Minxia ^{b, c, d}, Wang, Mingfang ^{b, c, d}, Pan, Jinshui ^{b, c, d, ⁎⁎⁎}, Lin, Su ^{b, c, d, ⁎⁎}, Zhu, Yueyong ^{b, c, d, ⁎}

Source: In Clinical Nutrition February 2025 45:136-147

Nicotinamide riboside abrogates lipopolysaccharide-induced inflammation and mitochondrial dysfunction in microglia through the AMP-activated protein kinase-sirtuin 3 signaling pathway

Authors: Moon, Chae Young, Park, Jimin, Shin, Eun Jeong, Kang, Hyunju ^⁎

Source: In Food Bioscience January 2025 63

The role of AMP-activated protein kinase activators on energy balance and cellular metabolism in type 2 diabetes mellitus

Authors: Aydin, Saliha ^{a, 1}, Tekinalp, Sevval Gulsah ^{a, b, 1}, Tuzcu, Bilge ^{c, d}, Cam, Furkan ^e, Sevik, Mehmet Orkun ^e, Tatar, Esra ^c, Kalaskar, Deepak ^f, Cam, Muhammet Emin ^{f, g, h, i, ⁎}

Source: In Obesity Medicine January 2025 53

FSTL1 protects against acute aortic dissection by suppressing vascular smooth muscle cell phenotypic switching and degradation of the extracellular matrix

Authors: Li, Jun-ping ^{a, b, 1}, He, Wan-bing ^{b, 1}, Xu, Shu-wan ^{e, 1}, Liu, Juan-zhang ^{b, d}, Huang, Zhao-qi ^{b, d}, Li, Chang-ping ^{b, d}, Huang, Chun-ling ^d, Mai, Pei-biao ^g, Geng, Deng-feng ^{b, d}, Qiu, Xiao-fu ^a, Liu, Zhao-yu ^{d, f, ⁎⁎⁎}, Zhang, Kun ^{c, ⁎⁎}, Zhou, Shu-xian ^{b, d, ⁎}

Source: In Journal of Molecular and Cellular Cardiology January 2025 198:60-73

Corrigendum: (Pro)renin receptor aggravates myocardial pyroptosis in diabetic cardiomyopathy through AMPK-NLRP3 pathway

Authors: Shengnan Li, Jingjing Zhang, Yuewen Zhao, Li Kang, Haipeng Jie, Bo Dong

Source: Frontiers in Pharmacology, Vol 15 (2024)

Subject Terms: (Pro)renin receptor, diabetic cardiomyopathy, pyroptosis, NLRP3, AMPK (AMP-activated protein kinase), Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2024.1532331/full; https://doaj.org/toc/1663-9812

Access URL: https://doaj.org/article/8593eb988b134281ae4252b4abb5e323

Upregulation of ALOX12−12-HETE pathway impairs AMPK-dependent modulation of vascular metabolism in ApoE/LDLR−/− mice

Authors: Mariola Olkowicz, Agnieszka Karas, Piotr Berkowicz, Patrycja Kaczara, Agnieszka Jasztal, Zuzanna Kurylowicz, Filip Fedak, Hernando Rosales-Solano, Kanchan Sinha Roy, Agnieszka Kij, Elzbieta Buczek, Janusz Pawliszyn, Stefan Chlopicki

Source: Pharmacological Research, Vol 210, Iss , Pp 107478- (2024)

Subject Terms: 12-lipoxygenase, Vascular energy metabolism, AMP-activated protein kinase (AMPK), Mitochondrial respiration, Vascular inflammation, Atherosclerosis, Therapeutics. Pharmacology, RM1-950

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Relation: http://www.sciencedirect.com/science/article/pii/S1043661824004237; https://doaj.org/toc/1096-1186

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An AMP‐activated protein kinase‐PGC‐1α axis mediates metabolic plasticity in glioblastoma

Authors: Benedikt Sauer, Jan Kueckelhaus, Nadja I. Lorenz, Süleyman Bozkurt, Dorothea Schulte, Jan‐Béla Weinem, Mohaned Benzarti, Johannes Meiser, Hans Urban, Giulia Villa, Patrick N. Harter, Christian Münch, Johannes Rieger, Joachim P. Steinbach, Dieter Henrik Heiland, Michael W. Ronellenfitsch

Source: Clinical and Translational Medicine, Vol 14, Iss 11, Pp n/a-n/a (2024)

Subject Terms: AMP‐activated protein kinase, glioblastoma, hypoxia, metabolic plasticity, PGC‐1α, PPARGC1A, Medicine (General), R5-920

File Description: electronic resource

Relation: https://doaj.org/toc/2001-1326

Access URL: https://doaj.org/article/953fce7d5fd0419cb7f6878acc45a495

Aerobic exercise attenuates insulin resistance via restoring branched chain amino acids homeostasis in obese mice

Authors: Wei Cao, Yajin Liu, Hao Wei, Yunfeng Dong, Haipeng Sun, Xuejiao Zhang, Junqiang Qiu

Source: Frontiers in Nutrition, Vol 11 (2024)

Subject Terms: aerobic exercise, branched-chain amino acids, mammalian target of rapamycin, AMP-activated protein kinase, insulin resistance, Nutrition. Foods and food supply, TX341-641

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnut.2024.1451429/full; https://doaj.org/toc/2296-861X

Access URL: https://doaj.org/article/99422d51a9f545dc95508073696dab12

Methionine restriction alleviates diabetes-associated cognitive impairment via activation of FGF21

Authors: Yuyu Zhang, Yajie Wang, Yiju Li, Jingxi Pang, Annika Höhn, Weixuan Dong, Rui Gao, Yan Liu, Da Wang, Yongbo She, Rui Guo, Zhigang Liu

Source: Redox Biology, Vol 77, Iss , Pp 103390- (2024)

Subject Terms: Methionine restriction, Diabetes-associated cognitive impairment, Fibroblast growth factor 21, Glucose metabolism, Glucose transporter proteins, AMP-Activated protein kinase, Medicine (General), R5-920, Biology (General), QH301-705.5

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2213231724003689; https://doaj.org/toc/2213-2317

Access URL: https://doaj.org/article/d91157d72936460fba34bd62665cbb5d

miR‐4448/Girdin/Akt/AMPK axis inhibits EZH2‐mediated EMT and tumorigenesis in small‐cell lung cancer

Authors: Nobuyuki Koyama, Yuichi Ishikawa, Hiromitsu Ohta, Takuya Aoki, Hiroyuki Kyoyama, Kazutetsu Aoshiba, Kazutsugu Uematsu

Source: Cancer Medicine, Vol 13, Iss 19, Pp n/a-n/a (2024)

Subject Terms: Akt, AMP‐activated protein kinase, epithelial‐mesenchymal transition, enhancer of zeste homolog 2, Girdin, miR‐4448, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2045-7634

Access URL: https://doaj.org/article/16b95dd534334f368d8c15b4d894f5d4