Cancer stem cell populations are resistant to 5-aminolevulinic acid-photodynamic therapy (5-ALA-PDT)

Authors: Chantel P. J. Rice, Vipin Shankar Chelakkot, Noah T. Conohan, Kensuke Hirasawa

Source: Scientific Reports, Vol 15, Iss 1, Pp 1-9 (2025)

Subject Terms: 5-aminolevulinic acid (5-ALA), Photodynamic therapy (PDT), Cancer stem cells (CSCs), CD133, 5-ALA-PDT resistance, Medicine, Science

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Relation: https://doaj.org/toc/2045-2322

Access URL: https://doaj.org/article/e575c89b696544f1a6a02a1b167f189f

Results of microsurgical resection of glioblastomas under endoscopic and fluorescent control

Authors: A. Yu. Rynda, V. E. Olyushin, D. M. Rostovtsev, Yu. M. Zabrodskaya, G. V. Papayan

Source: Biomedical Photonics, Vol 13, Iss 3, Pp 20-30 (2024)

Subject Terms: glioblastoma, endoscopy, fluorescent resection, results, survival, 5-ala, chlorin e6, Medical technology, R855-855.5

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Relation: https://www.pdt-journal.com/jour/article/view/659; https://doaj.org/toc/2413-9432

Access URL: https://doaj.org/article/2a1d1c431e67442a977c0f390a6a5c53

Comparison of photodynamic therapy and LEEP in women of reproductive age with cervical squamous intraepithelial neoplasia 2 (CIN2): A prospective observational study in China

Authors: Cheng Li, Xuanhui Wang, Qiulin Cui, Mian He, Ming Chen

Source: Photodiagnosis and Photodynamic Therapy, Vol 52, Iss , Pp 104496- (2025)

Subject Terms: high-grade squamous intraepithelial lesion (HSIL), Cervical intraepithelial neoplasia grade 2 (CIN2), 5-aminolevulinic acid photodynamic therapy (5-ALA PDT), loop electrosurgical excision procedure (LEEP), human papilloma virus (HPV), Medicine (General), R5-920

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Relation: http://www.sciencedirect.com/science/article/pii/S1572100025000262; https://doaj.org/toc/1572-1000

Access URL: https://doaj.org/article/c3fd1e4a7908426d802e38e7b0acf2f2

Studies related to the enhanced the effect of 5-aminolevulinic acid-based photodynamic therapy combined with tirapazamine

Authors: Qian Wang, Yuping Suo, Rui Shi, Yulan Wang

Source: Photodiagnosis and Photodynamic Therapy, Vol 49, Iss , Pp 104287- (2024)

Subject Terms: Photodynamic therapy, Tirapazamine, Ovarian cancer, Hypoxia, Apoptosis, 5-ALA, Medicine (General), R5-920

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Relation: http://www.sciencedirect.com/science/article/pii/S1572100024003247; https://doaj.org/toc/1572-1000

Access URL: https://doaj.org/article/b8d68fe191c9409fb0a247964b83fdb7

Effects of 5-Aminolevulinic Acid (5-ALA) on Morphological and Physiological Characteristics of Grapevine against Salt Stress

Authors: Selda Daler, Yılmaz Özkol

Source: Turkish Journal of Agriculture: Food Science and Technology, Vol 12, Iss 4, Pp 575-585 (2024)

Subject Terms: 5-aminolevulinic acid (5-ala), 41 b, american grapevine rootstock, nacl, salinity stress, Agriculture, Agriculture (General), S1-972

File Description: electronic resource

Relation: https://www.agrifoodscience.com/index.php/TURJAF/article/view/6711; https://doaj.org/toc/2148-127X

Access URL: https://doaj.org/article/3696076a36ee40d6bbaeed9f3218d55f

Carboxymethyl chitosan-based nanoparticles of acid response for the synergistic anti-tumor effect of PDT and chemotherapy

Authors: Zhang, Haiyun ^{a, b, 1}, Wang, Guifang ^{b, 1}, Li, Yuxin ^a, Wen, Ying ^a, Zhang, Yan ^{a, ⁎}, Wang, Qiangsong ^{a, ⁎}

Source: In International Journal of Biological Macromolecules November 2024 280 Part 3

ALA-RDT in GBM: protocol of the phase I/II dose escalation trial of radiodynamic therapy with 5-Aminolevulinic acid in patients with recurrent glioblastoma

Authors: Niklas Benedikt Pepper, Hans Theodor Eich, Michael Müther, Michael Oertel, Stephan Rehn, Dorothee Cäcilia Spille, Walter Stummer

Source: Radiation Oncology, Vol 19, Iss 1, Pp 1-8 (2024)

Subject Terms: Glioblastoma, 5-ALA, Radiodynamic therapy, Radiation therapy, Radiosensitizer, Recurrent glioblastoma, Medical physics. Medical radiology. Nuclear medicine, R895-920, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

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Relation: https://doaj.org/toc/1748-717X

Access URL: https://doaj.org/article/f3cff0fb0d0641168e753c0de641fb38

In Situ Light-Source Delivery During 5-Aminulevulinic Acid-Guided High-Grade Glioma Resection: Spatial, Functional and Oncological Informed Surgery

Authors: José Pedro Lavrador, Francesco Marchi, Ali Elhag, Nida Kalyal, Engelbert Mthunzi, Mariam Awan, Oliver Wroe-Wright, Alba Díaz-Baamonde, Ana Mirallave-Pescador, Zita Reisz, Richard Gullan, Francesco Vergani, Keyoumars Ashkan, Ranjeev Bhangoo

Source: Biomedicines, Vol 12, Iss 12, p 2748 (2024)

Subject Terms: 5-ALA, blue-light source, glioblastoma, surgery, Spectra, MIPS, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/12/2748; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/4c76f6031de74b4ca2cd08334d0219d2

Noninvasive Ultra Low Intensity Light Photodynamic Treatment of Glioblastoma with Drug Augmentation: LoGlo PDT Regimen

Authors: Richard E. Kast, Anton P. Kast, Jürgen Arnhold, Felix Capanni, Laura N. Milla Sanabria, Nicolas Bader, Bruno Marques Vieira, Alex Alfieri, Georg Karpel-Massler, Erasmo Barros da Silva

Source: Brain Sciences, Vol 14, Iss 12, p 1164 (2024)

Subject Terms: 5-ALA, glioblastoma, noninvasive, photodynamic treatment, repurposing, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/14/12/1164; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/5771b53bf2504599980db9568defd49f

Analysis of the Porphyrin Peak Shift and Fluorescence Lifetime in Gliomas with Different Tumor Grades, Intratumoral Regions, and Visible Fluorescence Status

Authors: Lisa Irina Körner, David Reichert, Marco Andreana, Angelika Unterhuber, Mikael T. Erkkilae, Jessica Makolli, Barbara Kiesel, Mario Mischkulnig, Thomas Rötzer-Pejrimovsky, Adelheid Wöhrer, Mitchel S. Berger, Rainer Leitgeb, Georg Widhalm

Source: Diagnostics, Vol 14, Iss 23, p 2651 (2024)

Subject Terms: protoporphyrin IX, 5-ALA, fluorescence lifetime, glioma, intraoperative visualization, Medicine (General), R5-920

File Description: electronic resource

Relation: https://www.mdpi.com/2075-4418/14/23/2651; https://doaj.org/toc/2075-4418

Access URL: https://doaj.org/article/010759b5df084f98baeab993b84cf069

Effective Fluorescence Control for TUR of the Bladder

Authors: Loshchenov, M., Kalyagina, N., Yagudaev, D., Borodkin, A., Kozlikina, E., Kustov, D., Amouroux, M., Daul, C., Moskalev, A., Blondel, W.

Source: 2022 International Conference Laser Optics (ICLO) Laser Optics (ICLO), 2022 International Conference. :1-1 Jun, 2022

Relation: 2022 International Conference Laser Optics (ICLO)

A novel PDT: 5-aminolevulinic acid combined 450 nm blue laser photodynamic therapy significantly promotes cell death of HR-HPV infected cells

Authors: Yuqing Chen, Yibo Mei, Lijiang Gu, Xing Li, Peng Guo, Lihong Chen, Dalin He

Source: Artificial Cells, Nanomedicine, and Biotechnology, Vol 51, Iss 1, Pp 22-32 (2023)

Subject Terms: HPV infection, photodynamic therapy, 5-aminolevulinic acid (5-ALA), 450 nm, cell apoptosis, reactive oxygen species（ROS）, Biotechnology, TP248.13-248.65, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2169-1401; https://doaj.org/toc/2169-141X

Access URL: https://doaj.org/article/305570056dd34be681615cc44def95a0

Photodynamic therapy in neurooncology

Authors: V. E. Olyushin, K. K. Kukanov, A. S. Nechaeva, S. S. Sklyar, A. E. Vershinin, M. V. Dikonenko, A. S. Golikova, A. S. Mansurov, B. I. Safarov, A. Y. Rynda, G. V. Papayan

Source: Biomedical Photonics, Vol 12, Iss 3, Pp 25-35 (2023)

Subject Terms: photodynamic therapy, photosensitizer, photoditazine, 5-ala, neurooncology, apoptosis, necrosis, meningioma, recurrence, glioblastoma, metastasis, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://www.pdt-journal.com/jour/article/view/606; https://doaj.org/toc/2413-9432

Access URL: https://doaj.org/article/9bf567ecee9a4db2810da06b9e65ba10

In Vivo Nuclear Molecular Imaging in Drug Development and Pharmacological Research

Contributors: Yue, Xuyi

Subject Terms: nanoparticle, multimodal imaging, photoacoustic, heterobivalent peptide, Alzheimer’s disease, amyloid-beta, animal model, astrocyte, blood–brain barrier, imaging, metabolism, microglia, neuroinflammation, neurotransmitter receptors, positron emission tomography, synaptic density, vascular imaging, FDG, PET/CT, microvasculature imaging, ABC-transporter, drug-induced liver injury, hepatotoxicity, organic anion-transporting polypeptide, pharmacokinetics, liver function, SLC-transporter, V/Q PET/CT, [68Ga]Ga-MAA, 68Ga-labelled carbon nanoparticles, glioblastoma, fluorescence guided surgery, 5-ALA, fluorescein, NIR-AZA, magnetic resonance imaging, high resolution, hybrid imaging, psychiatric disorders, extracellular vesicles (EVs), umbilical cord mesenchymal stem cell (UCMSC), diabetes, I-124, positron emission tomography (PET), intravenous (I.V.) administration, intra-arterial (I.A.) administration, biodistribution, fluorine-18, PET, oxime, PSMA, lipophilicity, radiometals, copper-61, liquid targets, post-processing, [61Cu]Cu-DOTA-NOC, [61Cu]Cu-DOTA-TOC, [61Cu]Cu-DOTA-TATE, FAP, 99mTc-FAP inhibitor, 99mTc-labeled iFAP, tumor microenvironment, SPECT, GluN1/2B receptors, NMDA, [3H]ifenprodil, σ1 and σ2 receptors, receptor occupancy, PET imaging, drug development, neurodegenerative diseases, Research and information: general, Biology, life sciences

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Access URL: https://directory.doabooks.org/handle/20.500.12854/100794
https://mdpi.com/books/pdfview/book/7256

Enlightening the invisible: Applications, limits and perspectives of intraoperative fluorescence in neurosurgery

Authors: Cossu, Giulia ^{a, b, ⁎}, Le Van, Tuan ^b, Kerherve, Luc ^b, Houidi, Sayda A. ^b, Morlaix, Edouard ^b, Bonneville, Florent ^b, Chapon, Renan ^b, Baland, Olivier ^b, Cao, Catherine ^b, Lleu, Maxime ^b, Farah, Walid ^b, El Cadhi, Ahmed ^b, Beaurain, Jacques ^b, Picart, Thiebaud ^{c, d, e}, Xu, Bin ^f, Berhouma, Moncef ^{b, g}

Source: In Brain and Spine 2024 4

Fluorescence guidance in skull base surgery: Applications and limitations – A systematic review

Authors: Suero Molina, Eric ^{a, b, ⁎}, Bruneau, Michael ^c, Reuter, Gilles ^d, Shahein, Mostafa ^e, Cavallo, Luigi M. ^f, Daniel, Roy T. ^g, Kasper, Ekkehard M. ^h, Froelich, Sebastien ⁱ, Jouanneau, Emanuel ^j, Manet, Romain ^j, Messerer, Mahmoud ^f, Mazzatenta, Diego ^k, Meling, Torstein R. ^l, Roche, Pierre-Hugues ^m, Schroeder, Henry WS. ⁿ, Tatagiba, Marcos ^o, Visocchi, Massimiliano ^p, Prevedello, Daniel M. ^q, Stummer, Walter ^a, Cornelius, Jan F. ^r

Source: In Brain and Spine 2024 4

Benefits of combined use of 68−Ga Dotatoc and 5-ALA fluorescence for recurrent atypical skull-base meningioma after previous microsurgery and Gamma Knife radiosurgery: a case report

Authors: Iulia Peciu-Florianu, Alice Jaillard, Constantin Tuleasca, Nicolas Reyns

Source: Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-6 (2023)

Subject Terms: Meningioma, Atypical, Recurrent, Gamma Knife, 5-ALA, Fluorescence, Medicine

File Description: electronic resource

Relation: https://doaj.org/toc/1752-1947

Access URL: https://doaj.org/article/6619a8c2ee7f4231a30241f082994784

Effects of 5-Aminolevulinic Acid Supplementation on Gas Production, Fermentation Characteristics, and Bacterial Community Profiles In Vitro

Authors: Zhenkai Hao, Zhuangzhuang Guo, Ning Zhang, Jing Wang, Jiabao Xu, Weiyu Zhang, Qiang Liu, Cong Wang, Yawei Zhang, Yuanqing Zhang

Source: Microorganisms, Vol 12, Iss 9, p 1867 (2024)

Subject Terms: 5-ALA, beef cattle, in vitro rumen fermentation, bacterial diversity, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2076-2607/12/9/1867; https://doaj.org/toc/2076-2607

Access URL: https://doaj.org/article/8bf8dc2dadae4563abbe1666085212e9

Fluorescence-Enhanced Assessments for Human Breast Cancer Cell Characterizations

Authors: Mahsa Ghezelbash, Batool Sajad, Shadi Hojatizadeh

Source: Photonics, Vol 11, Iss 8, p 746 (2024)

Subject Terms: fluorescence, breast cancer, detection, auto-fluorescence, key fluorophores, 5-ALA, Applied optics. Photonics, TA1501-1820

File Description: electronic resource

Relation: https://www.mdpi.com/2304-6732/11/8/746; https://doaj.org/toc/2304-6732

Access URL: https://doaj.org/article/ee3864f26e0b4ba7a0cd934baead4e1d

Plant growth regulators mitigate oxidative damage to rice seedling roots by NaCl stress

Authors: Yaxin Wang, Li-ming Zhao, Naijie Feng, Dianfeng Zheng, Xue Feng Shen, Hang Zhou, Wenxin Jiang, Youwei Du, Huimin Zhao, Xutong Lu, Peng Deng

Source: PeerJ, Vol 12, p e17068 (2024)

Subject Terms: Rice root system, NaCl stress, 5-ALA, DTA-6, Physiological properties, Keywords Rice root system, Medicine, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://peerj.com/articles/17068.pdf; https://peerj.com/articles/17068/; https://doaj.org/toc/2167-8359

Access URL: https://doaj.org/article/13e180f8e9814e9292ecda9e215d0a55