Bispecific T cell engager-armed T cells targeting integrin ανβ6 exhibit enhanced T cell redirection and antitumor activity in cholangiocarcinoma

Authors: Suwanchiwasiri, Kwanpirom ^{a, b, c}, Phanthaphol, Nattaporn ^{b, c, d, ⁎}, Somboonpatarakun, Chalermchai ^{b, c}, Yuti, Pornpimon ^{b, c}, Sujjitjoon, Jatuporn ^{b, c}, Luangwattananun, Piriya ^{b, c}, Maher, John ^e, Yenchitsomanus, Pa‑thai ^{b, c}, Junking, Mutita ^{b, c, ⁎⁎}

Source: In Biomedicine & Pharmacotherapy June 2024 175

A preclinical platform for assessing long-term drug efficacy exploiting mechanically tunable scaffolds colonized by a three-dimensional tumor microenvironment

Authors: Elly De Vlieghere, Koen Van de Vijver, Eva Blondeel, Nathan Carpentier, Rouba Ghobeira, Jarne Pauwels, Sebastian Riemann, Manon Minsart, Charlotte Fieuws, Johanna Mestach, Ans Baeyens, Nathalie De Geyter, Charlotte Debbaut, Hannelore Denys, Benedicte Descamps, Kathleen Claes, Anne Vral, Jo Van Dorpe, Kris Gevaert, Bruno G. De Geest, Wim Ceelen, Sandra Van Vlierberghe, Olivier De Wever

Source: Biomaterials Research, Vol 27, Iss 1, Pp 1-18 (2023)

Subject Terms: 3D cancer model, Long-term, Drug evaluation, Pre-clinical, Micro-environment, Stiffness, Medical technology, R855-855.5

File Description: electronic resource

Relation: https://doaj.org/toc/2055-7124

Access URL: https://doaj.org/article/3e5a307685aa4c44b056bfedd46942cf

Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids

Authors: Adriana Romanzi, Fabiola Milosa, Gemma Marcelli, Rosina Maria Critelli, Simone Lasagni, Isabella Gigante, Francesco Dituri, Filippo Schepis, Massimiliano Cadamuro, Gianluigi Giannelli, Luca Fabris, Erica Villa

Source: Biomedicines, Vol 12, Iss 1, p 87 (2023)

Subject Terms: proangiogenic factors, VEGF, Angiopoietin-2, 3D cancer model, migration, invasiveness, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/12/1/87; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/3ff6ec006b9c4f7a89266877ad4a75b1

3-Dimensional coculture of breast cancer cell lines with adipose tissue–Derived stem cells reveals the efficiency of oncolytic Newcastle disease virus infection via labeling technology

Authors: Marwa Ibrahim Salman, Ahmed Majeed Al-Shammari, Mahfodha Abbas Emran

Source: Frontiers in Molecular Biosciences, Vol 9 (2022)

Subject Terms: labeled viruses, virotherapy, breast cancer, adipose tissue–derived adult stem cell, 3D cancer model, coculture, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmolb.2022.754100/full; https://doaj.org/toc/2296-889X

Access URL: https://doaj.org/article/3f536bced4784fed8dc7a1556cbe5e39

Development of the Follow-Up Human 3D Oral Cancer Model in Cancer Treatment

Authors: Kazuyo Igawa, Kenji Izumi, Yoshinori Sakurai

Source: BioTech, Vol 12, Iss 2, p 35 (2023)

Subject Terms: 3D cancer model, preclinical study, cancer treatment, quality of life, multidisciplinary treatment, Biotechnology, TP248.13-248.65

File Description: electronic resource

Relation: https://www.mdpi.com/2673-6284/12/2/35; https://doaj.org/toc/2673-6284

Access URL: https://doaj.org/article/44a128e71cf9498a88008ab55da43d95

GelMA, Click-Chemistry Gelatin and Bioprinted Polyethylene Glycol-Based Hydrogels as 3D Ex Vivo Drug Testing Platforms for Patient-Derived Breast Cancer Organoids

Authors: Nathalie Bock, Farzaneh Forouz, Luke Hipwood, Julien Clegg, Penny Jeffery, Madeline Gough, Tirsa van Wyngaard, Christopher Pyke, Mark N. Adams, Laura J. Bray, Laura Croft, Erik W. Thompson, Thomas Kryza, Christoph Meinert

Source: Pharmaceutics, Vol 15, Iss 1, p 261 (2023)

Subject Terms: 3D cancer model, patient-derived organoid, hydrogel, GelMA, gelatin, polyethylene glycol, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/1/261; https://doaj.org/toc/1999-4923

Access URL: https://doaj.org/article/5a542fd7c7cc4e5e896ca4a5ca644885

Semi-Synthetic Click-Gelatin Hydrogels as Tunable Platforms for 3D Cancer Cell Culture

Authors: Luke Hipwood, Julien Clegg, Angus Weekes, Jordan W. Davern, Tim R. Dargaville, Christoph Meinert, Nathalie Bock

Source: Gels, Vol 8, Iss 12, p 821 (2022)

Subject Terms: gelatin, hydrogels, 3D cancer model, extracellular matrix, click chemistry, cell culture, Science, Chemistry, QD1-999, Inorganic chemistry, QD146-197, General. Including alchemy, QD1-65

File Description: electronic resource

Relation: https://www.mdpi.com/2310-2861/8/12/821; https://doaj.org/toc/2310-2861

Access URL: https://doaj.org/article/3fbd8d9ff7cd42cabe099ab2f9a69e12

Cell-Laden Hydrogel as a Clinical-Relevant 3D Model for Analyzing Neuroblastoma Growth, Immunophenotype, and Susceptibility to Therapies

Authors: Alessandra Marrella, Alessandra Dondero, Maurizio Aiello, Beatrice Casu, Daniel Olive, Stefano Regis, Cristina Bottino, Daniela Pende, Raffaella Meazza, Guido Caluori, Roberta Castriconi, Silvia Scaglione

Source: Frontiers in Immunology, Vol 10 (2019)

Subject Terms: 3D cancer model, neuroblastoma, NK cells, PVR, KIRS/HLA-I, PD-Ls, Immunologic diseases. Allergy, RC581-607

File Description: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2019.01876/full; https://doaj.org/toc/1664-3224

Access URL: https://doaj.org/article/a38c4171e38547d9b6023846f4c5d30a

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Pioneering new 3D cancer model to speed new treatments

Source: domain-B (India), May 8, 2018 News, 2pp