Carboxylesterase 1-mediated endocannabinoid metabolism in skin: role in melanoma progression in BRaf V600E /Pten −/− mice

Authors: Veronika Morozova, Daniele Pellegata, Roch-Philippe Charles, Jürg Gertsch

Source: Cancer & Metabolism, Vol 13, Iss 1, Pp 1-18 (2025)

Subject Terms: CES1, Melanoma, 2-AG, Lipidomics, Targeted Metabolomics, Chemoproteomics, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/2049-3002

Access URL: https://doaj.org/article/d4f71b42060048b5ae80177391328e34

Sex-specific alterations in emotional behavior and neurotransmitter systems in LPA1 receptor-deficient mice

Authors: Sánchez-Marín, Laura ^{a, b, 1}, Jiménez-Castilla, Violeta ^{a, b, 1}, Flores-López, María ^{a, b}, Navarro, Juan A. ^{a, c}, Gavito, Ana ^{a, c}, Blanco-Calvo, Eduardo ^d, Santín, Luis J. ^d, Pavón-Morón, Francisco J. ^{a, e, f}, Rodríguez de Fonseca, Fernando ^{a, c, g, ⁎⁎}, Serrano, Antonia ^{a, b, ⁎}

Source: In Neuropharmacology 1 May 2025 268

Relationship between sex, APOE genotype, endocannabinoids and cognitive change in older adults with metabolic syndrome during a 3-year Mediterranean diet intervention

Authors: Natalia Soldevila-Domenech, Beatriz Fagundo, Aida Cuenca-Royo, Laura Forcano, Maria Gomis-González, Anna Boronat, Antoni Pastor, Olga Castañer, Maria Dolores Zomeño, Albert Goday, Mara Dierssen, Khashayar Baghizadeh Hosseini, Emilio Ros, Dolores Corella, Miguel Ángel Martínez-González, Jordi Salas-Salvadó, Fernando Fernández-Aranda, Montserrat Fitó, Rafael de la Torre

Source: Nutrition Journal, Vol 23, Iss 1, Pp 1-20 (2024)

Subject Terms: Mediterranean diet, Endocannabinoids, Sex differences, Cognition, Metabolic syndrome, 2-AG, Nutrition. Foods and food supply, TX341-641, Nutritional diseases. Deficiency diseases, RC620-627

File Description: electronic resource

Relation: https://doaj.org/toc/1475-2891

Access URL: https://doaj.org/article/69ef19b2d9fa4c6c931206bbf3e76f96

Analgesic Properties of Next-Generation Modulators of Endocannabinoid Signaling: Leveraging Modern Tools for the Development of Novel Therapeutics

Authors: Singh, Simar, Ellioff, Kaylin J., Bruchas, Michael R., Land, Benjamin B. ¹, Stella, Nephi ^{1, *}

Source: In The Journal of Pharmacology and Experimental Therapeutics November 2024 391(2):162-173

The Potential of Cannabichromene (CBC) as a Therapeutic Agent

Authors: Sepulveda, Diana E., Vrana, Kent E., Kellogg, Joshua J., Bisanz, Jordan E., Desai, Dhimant, Graziane, Nicholas M., Raup-Konsavage, Wesley M. ^*

Source: In The Journal of Pharmacology and Experimental Therapeutics November 2024 391(2):206-213

The Interplay of Exogenous Cannabinoid Use on Anandamide and 2-Arachidonoylglycerol in Anxiety: Results from a Quasi-Experimental Ad Libitum Study

Authors: Renée Martin-Willett, Carillon J. Skrzynski, Ethan M. Taylor, Cristina Sempio, Jost Klawitter, L. Cinnamon Bidwell

Source: Pharmaceuticals, Vol 17, Iss 10, p 1335 (2024)

Subject Terms: THC, CBD, anxiety, AEA, 2-AG, cannabinoid content, Medicine, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/10/1335; https://doaj.org/toc/1424-8247

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Reactive spinal glia convert 2-AG to prostaglandins to drive aberrant astroglial calcium signaling

Authors: Klaudia Dócs, Anita Balázs, Ildikó Papp, Peter Szücs, Zoltán Hegyi

Source: Frontiers in Cellular Neuroscience, Vol 18 (2024)

Subject Terms: CB1, 2-AG, COX-2, cannabinoid, prostaglandin, calcium signaling, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fncel.2024.1382465/full; https://doaj.org/toc/1662-5102

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Attenuation of allodynia and microglial reactivity by inhibiting the degradation of 2-arachidonoylglycerol following injury to the trigeminal nerve in mice

Authors: Kamimura, Rantaro ^{a, ∗}, Hossain, Mohammad Zakir ^b, Takahashi, Kojiro ^a, Saito, Isao ^a, Kitagawa, Junichi ^b

Source: In Heliyon August 2022 8(8)

Orexin induces the production of an endocannabinoid-derived lysophosphatidic acid eliciting hypothalamic synaptic loss in obesity

Authors: Alba Clara Fernández-Rilo, Nicola Forte, Letizia Palomba, Lea Tunisi, Fabiana Piscitelli, Roberta Imperatore, Alfonso Di Costanzo, Vincenzo Di Marzo, Luigia Cristino

Source: Molecular Metabolism, Vol 72, Iss , Pp 101713- (2023)

Subject Terms: Hypothalamus, Obesity, α-MSH, Orexin/hypocretin, 2-Arachidonoyl-glycerol, 2-AG, Internal medicine, RC31-1245

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2212877823000479; https://doaj.org/toc/2212-8778

Access URL: https://doaj.org/article/9264eccabc294d96960ef6595ab4fb4d

Cell-autonomous and differential endocannabinoid signaling impacts the development of presynaptic retinal ganglion cell axon connectivity in vivo

Authors: Rodrigo Del Rio, Rosa G. Serrano, Eric Gomez, Joshua C. Martinez, Marina A. Edward, Rommel A. Santos, Kenneth S. Diaz, Susana Cohen-Cory

Source: Frontiers in Synaptic Neuroscience, Vol 15 (2023)

Subject Terms: Xenopus laevis, live imaging, optic tectum, knockdown, anandamide (AEA), 2-Arachidonoylglycerol (2-AG), Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnsyn.2023.1176864/full; https://doaj.org/toc/1663-3563

Access URL: https://doaj.org/article/ee754b06fb0e4cd2882a1c14d0998637

ABHD6 and MAGL control 2-AG levels in the PAG and allodynia in a CSD-induced periorbital model of headache

Authors: Erika Liktor-Busa, Aidan A. Levine, Seph M. Palomino, Simar Singh, Jared Wahl, Todd W. Vanderah, Nephi Stella, Tally M. Largent-Milnes

Source: Frontiers in Pain Research, Vol 4 (2023)

Subject Terms: 2-AG, endocannabinoid, migraine, MAGL, ABHD6, PAG, Neurology. Diseases of the nervous system, RC346-429

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpain.2023.1171188/full; https://doaj.org/toc/2673-561X

Access URL: https://doaj.org/article/d4532d8037154f8e87e75dc035f497b3

Cannabinoids and neuroinflammation: Therapeutic implications

Authors: Brian E. Leonard, Feyza Aricioglu

Source: Journal of Affective Disorders Reports, Vol 12, Iss , Pp 100463- (2023)

Subject Terms: Phytocannabinoids, THC and CBD, endogenous cannabinoids, anadamide and 2-AG, Microglia, Neuroinflammation, Mental healing, RZ400-408

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2666915323000021; https://doaj.org/toc/2666-9153

Access URL: https://doaj.org/article/b3ae701c809145218eceeef34ed6f730

Up-regulation of CB1 cannabinoid receptors located at glutamatergic terminals in the medial prefrontal cortex of the obese Zucker rat

Authors: Leyre Echeazarra, Sergio Barrondo, Gontzal García del Caño, Itziar Bonilla-Del Río, Jon Egaña-Huguet, Nagore Puente, Xabier Aretxabala, Mario Montaña, Maider López de Jesús, Imanol González-Burguera, Miquel Saumell-Esnaola, María Aránzazu Goicolea, Pedro Grandes, Joan Sallés

Source: Frontiers in Neuroanatomy, Vol 16 (2022)

Subject Terms: obese Zucker rat, CB1 receptor, Gi/o proteins, 2-AG levels, medial prefrontal cortex, glutamatergic terminals, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnana.2022.1004702/full; https://doaj.org/toc/1662-5129

Access URL: https://doaj.org/article/70efecff7f434c68b2dafd26fc181ffd

Circulating Endocannabinoids and N-Acylethanolamines in Individuals with Cannabis Use Disorder—Preliminary Findings

Authors: Nadia Boachie, Erin Gaudette, Richard P. Bazinet, Lin Lin, Rachel F. Tyndale, Esmaeil Mansouri, Marilyn A. Huestis, Junchao Tong, Bernard Le Foll, Stephen J. Kish, Tony P. George, Isabelle Boileau

Source: Brain Sciences, Vol 13, Iss 10, p 1375 (2023)

Subject Terms: AEA, 2-AG, OEA, DHEA, NAE, N-acylethanolamines, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3425/13/10/1375; https://doaj.org/toc/2076-3425

Access URL: https://doaj.org/article/c15397b4384f4b5dbc0cffdffb8ba890

Development of a highly-specific 18F-labeled irreversible positron emission tomography tracer for monoacylglycerol lipase mapping

Authors: Zhen Chen, Wakana Mori, Jian Rong, Michael A. Schafroth, Tuo Shao, Richard S. Van, Daisuke Ogasawara, Tomoteru Yamasaki, Atsuto Hiraishi, Akiko Hatori, Jiahui Chen, Yiding Zhang, Kuan Hu, Masayuki Fujinaga, Jiyun Sun, Qingzhen Yu, Thomas L. Collier, Yihan Shao, Benjamin F. Cravatt, Lee Josephson, Ming-Rong Zhang, Steven H. Liang

Source: Acta Pharmaceutica Sinica B, Vol 11, Iss 6, Pp 1686-1695 (2021)

Subject Terms: Monoacylglycerol lipase (MAGL), Central nervous system (CNS), 2-Arachidonylglycerol (2-AG), Arachidonic acid (AA), Positron emission tomography (PET), Fluorine-18, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2211383521000381; https://doaj.org/toc/2211-3835

Access URL: https://doaj.org/article/6647b3af1e7f460aab63220f173d99be

The Long-Term Neuroprotective Effect of the Endocannabinoid 2-AG and Modulation of the SGZ’s Neurogenic Response after Neonatal Hypoxia-Ischemia

Authors: Gorane Beldarrain, Enrique Hilario, Idoia Lara-Celador, Marc Chillida, Ana Catalan, Antonia Ángeles Álvarez-Diaz, Daniel Alonso-Alconada

Source: Pharmaceutics, Vol 15, Iss 6, p 1667 (2023)

Subject Terms: neonatal hypoxia-ischemia, endocannabinoid system, 2-AG, neuroprotection, neurogenesis, Pharmacy and materia medica, RS1-441

File Description: electronic resource

Relation: https://www.mdpi.com/1999-4923/15/6/1667; https://doaj.org/toc/1999-4923

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Activity-Dependent Modulation of Tonic GABA Currents by Endocannabinoids in Hirudo verbana

Authors: Riley T. Paulsen, Brian D. Burrell

Source: Frontiers in Synaptic Neuroscience, Vol 14 (2022)

Subject Terms: endocannabinoids, 2-arachidonoylglycerol (2-AG), anandamide (AEA), TRPV, tonic inhibition, Hirudo verbana, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnsyn.2022.760330/full; https://doaj.org/toc/1663-3563

Access URL: https://doaj.org/article/498b4815e10541bf97d09dddf934bbe7

Cannabinoids accumulate in mouse breast milk and differentially regulate lipid composition and lipid signaling molecules involved in infant development

Authors: Clare T Johnson, Gabriel H Dias de Abreu, Ken Mackie, Hui-Chen Lu, Heather B Bradshaw

Source: BBA Advances, Vol 2, Iss , Pp 100054- (2022)

Subject Terms: Cannabidiol, CBD, ∆-9-tetrahydrocannabinol, THC, Milk, 2-AG, Biochemistry, QD415-436, Genetics, QH426-470

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S2667160322000151; https://doaj.org/toc/2667-1603

Access URL: https://doaj.org/article/6c288daf76e14bd484f72a0a9da89e0d

Jalur Sinyal dan Metabolisme Endocannabinoid: Tinjauan Pustaka

Authors: Loo Hariyanto Raharjo, Harman Agusaputra

Source: Jurnal Ilmiah Kedokteran Wijaya Kusuma, Vol 8, Iss 1, Pp 117-136 (2019)

Subject Terms: Endocannabinoid, Anandamide (AEA), arachidonoyglycerol (2-AG), Jalur metabolik, Jalur transduksi sinyal, Medicine (General), R5-920, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://journal.uwks.ac.id/index.php/jikw/article/view/574; https://doaj.org/toc/1978-2071; https://doaj.org/toc/2580-5967

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2-Arachidonoylglycerol as an Endogenous Cue Negatively Regulates Attachment of the Mussel Perna viridis

Authors: Qi Dai, Zhi-Xuan Wang, Yan-Qing Sheng, Zhi-Wen Wu, Yan Qiu, Pei Su, Cai-Huan Ke, Dan-Qing Feng

Source: Frontiers in Marine Science, Vol 8 (2021)

Subject Terms: endocannabinoid, 2-AG, mussel, Perna viridis, attachment, Science, General. Including nature conservation, geographical distribution, QH1-199.5

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fmars.2021.719781/full; https://doaj.org/toc/2296-7745

Access URL: https://doaj.org/article/534e292d97cf4b93b03e64430378fd86