In vitro hepatic 3D cell models and their application in genetic toxicology: A systematic review

Authors: Štampar, Martina, Žegura, Bojana

Source: In Mutation Research - Genetic Toxicology and Environmental Mutagenesis November-December 2024 900

Degradation and toxicity of bisphenol A and S during cold atmospheric pressure plasma treatment

Authors: Kovačič, Ana, Modic, Martina, Hojnik, Nataša, Štampar, Martina, Gulin, Martin Rafael, Nannou, Christina, Koronaiou, Lelouda-Athanasia, Heath, David, Walsh, James L., Žegura, Bojana, Lambropoulou, Dimitra, Cvelbar, Uroš, Heath, Ester

Source: In Journal of Hazardous Materials 15 July 2023 454

Adverse (geno)toxic effects of bisphenol A and its analogues in hepatic 3D cell model

Authors: Sendra, Marta, Štampar, Martina, Fras, Katarina, Novoa, Beatriz, Figueras, Antonio, Žegura, Bojana

Source: In Environment International January 2023 171

HepG2 spheroids as a biosensor-like cell-based system for (geno)toxicity assessment

Authors: Štampar, Martina ^{a, b}, Žabkar, Sonja ^a, Filipič, Metka ^a, Žegura, Bojana ^{a, ∗}

Source: In Chemosphere March 2022 291 Part 1

Hepatocellular carcinoma (HepG2/C3A) cell-based 3D model for genotoxicity testing of chemicals

Authors: Štampar, Martina, Sedighi Frandsen, Helle, Rogowska-Wrzesinska, Adelina, Wrzesinski, Krzysztof, Filipič, Metka, Žegura, Bojana

Source: In Science of the Total Environment 10 February 2021 755 Part 2

Method to Disassemble Spheroids into Core and Rim for Downstream Applications Such as Flow Cytometry, Comet Assay, Transcriptomics, Proteomics, and Lipidomics

Authors: Frandsen, Helle Sedighi, Štampar, Martina, Vej-Nielsen, Joel Mario, Žegura, Bojana, Rogowska-Wrzesinska, Adelina

Source: Methods in molecular biology. 2273:173-188

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN625803017&indx=1&recIds=ETOCRN625803017

Application of advanced HepG2 3D cell model for studying genotoxic activity of cyanobacterial toxin cylindrospermopsin

Authors: Hercog, Klara, Štampar, Martina, Štern, Alja, Filipič, Metka, Žegura, Bojana

Source: In Environmental Pollution October 2020 265 Part B

Design and synthesis of 3,5-substituted 1,2,4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα

Authors: Loboda, Kaja Bergant, Valjavec, Katja, Štampar, Martina, Wolber, Gerhard, Žegura, Bojana, Filipič, Metka, Dolenc, Marija Sollner, Perdih, Andrej

Source: In Bioorganic Chemistry June 2020 99

Corrigendum to 'Degradation and toxicity of bisphenol A and S during cold atmospheric pressure plasma treatment' J. Hazard. Mater. 454(2023) Article no. 131478

Authors: Kovačič, Ana, Modic, Martina, Hojnik, Nataša, Štampar, Martina, Gulin, Martin Rafael, Nannou, Christina, Koronaiou, Lelouda-Athanasia, Heath, David, Walsh, James L., Žegura, Bojana, Lambropoulou, Dimitra, Cvelbar, Uroš, Heath, Ester

Source: Journal of hazardous materials. 457

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100196441973.0x000001&indx=1&recIds=ETOCvdc_100196441973.0x000001

Combined Toxic Effects of BPA and Its Two Analogues BPAP and BPC in a 3D HepG2 Cell Model.

Authors: Štampar, Martina¹ (AUTHOR), Ravnjak, Tim² (AUTHOR), Domijan, Ana-Marija³ (AUTHOR), Žegura, Bojana¹ (AUTHOR) bojana.zegura@nib.si

Source: Molecules. Apr2023, Vol. 28 Issue 7, p3085. 16p.

Subject Terms: *POISONS, *TOXICITY testing, *CELL survival, *REACTIVE oxygen species, *BINARY mixtures, *GENETIC toxicology

Structure-guided optimization of 4,6-substituted-1,3,5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα

Authors: Bergant, Kaja, Janežič, Matej, Valjavec, Katja, Sosič, Izidor, Pajk, Stane, Štampar, Martina, Žegura, Bojana, Gobec, Stanislav, Filipič, Metka, Perdih, Andrej

Source: In European Journal of Medicinal Chemistry 1 August 2019 175:330-348

Substituted 4,5′-Bithiazoles as Catalytic Inhibitors of Human DNA Topoisomerase IIα

Authors: Loboda, Kaja Bergant, Janežič, Matej, Štampar, Martina, Žegura, Bojana, Filipič, Metka, Perdih, Andrej

Source: JOURNAL OF CHEMICAL INFORMATION AND MODELING. 60(7):3662-3678

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCRN632689550&indx=1&recIds=ETOCRN632689550

Development of in vitro 3D cell model from hepatocellular carcinoma (HepG2) cell line and its application for genotoxicity testing

Authors: Štampar, Martina, Tomc, Jana, Filipič, Metka, Žegura, Bojana

Source: Archives of toxicology. 93(11):3321-3333

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100125619190.0x000001&indx=1&recIds=ETOCvdc_100125619190.0x000001

Structure-guided optimization of 4, 6-substituted-1, 3, 5-triazin-2(1H)-ones as catalytic inhibitors of human DNA topoisomerase IIα

Authors: Bergant, Kaja, Janežič, Matej, Valjavec, Katja, Sosič, Izidor, Pajk, Stane, Štampar, Martina, Žegura, Bojana, Gobec, Stanislav, Filipič, Metka, Perdih, Andrej

Source: European journal of medicinal chemistry. 175:330-348

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100097112491.0x000001&indx=1&recIds=ETOCvdc_100097112491.0x000001

Design and synthesis of 3, 5-substituted 1, 2, 4-oxadiazoles as catalytic inhibitors of human DNA topoisomerase IIα

Authors: Loboda, Kaja Bergant, Valjavec, Katja, Štampar, Martina, Wolber, Gerhard, Žegura, Bojana, Filipič, Metka, Dolenc, Marija Sollner, Perdih, Andrej

Source: Bioorganic chemistry. 99

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCvdc_100114407831.0x000001&indx=1&recIds=ETOCvdc_100114407831.0x000001

Impact of Deoxynivalenol and Zearalenone as Single and Combined Treatment on DNA, Cell Cycle and Cell Proliferation in HepG2 Cells.

Authors: Domijan, Ana-Marija, Hercog, Klara, Štampar, Martina, Gajski, Goran, Gerić, Marko, Sokolović, Marijana, Žegura, Bojana

Source: International Journal of Molecular Sciences; Feb2023, Vol. 24 Issue 4, p4082, 13p

Subject Terms: FUSARIUM toxins, CELL proliferation, ZEARALENONE, DEOXYNIVALENOL, CELL survival, DNA damage, CELL cycle

Adverse Toxic Effects of Tyrosine Kinase Inhibitors on Non-Target Zebrafish Liver (ZFL) Cells.

Authors: Kološa, Katja, Žegura, Bojana, Štampar, Martina, Filipič, Metka, Novak, Matjaž

Source: International Journal of Molecular Sciences; Feb2023, Vol. 24 Issue 4, p3894, 19p

Subject Terms: PROTEIN-tyrosine kinase inhibitors, GENETIC toxicology, SINGLE-strand DNA breaks, POISONS, LIVER cells, CELL cycle

Substituted 4,5′-Bithiazoles as Catalytic Inhibitors of Human DNA Topoisomerase IIα.

Authors: Bergant Loboda, Kaja, Janežič, Matej, Štampar, Martina, Žegura, Bojana, Filipič, Metka, Perdih, Andrej

Source: Journal of Chemical Information & Modeling; 7/27/2020, Vol. 60 Issue 7, p3662-3678, 17p

Characterization of In Vitro 3D Cell Model Developed from Human Hepatocellular Carcinoma (HepG2) Cell Line.

Authors: Štampar, Martina^1,2 (AUTHOR) martina.stampar@nib.si, Breznik, Barbara¹ (AUTHOR) barbara.breznik@nib.si, Filipič, Metka^1,2 (AUTHOR) metka.filipic@nib.si, Žegura, Bojana^1,2 (AUTHOR) Bojana.zegura@nib.si

Source: Cells (2073-4409). Dec2020, Vol. 9 Issue 12, p2557. 1p.

Subject Terms: *HEPATOCELLULAR carcinoma, *CELL lines, *LIVER cells, *GENETIC toxicology, *CELL analysis, *MOTION capture (Human mechanics)

(Invited) the Removal of Bisphenols from Wastewaters with Atmospheric Pressure Plasma.

Authors: Hojnik, Nataša, Kovačič, Ana, Modic, Martina, Štampar, Martina, Gulin, Martin Rafael, Nannou, Christina, Koronaiou, Lelouda-Athanasia, Heath, David, Walsh, James Leon, Žegura, Bojana, Lambropoulou, Dimitra, Cvelbar, Uros, Heath, Sr., Ester

Source: ECS Meeting Abstracts; 2023, Vol. MA2023-02 Issue 1, p1201-1201, 1p