Rottlerin Stimulates Exosome/Microvesicle Release Via the Increase of Ceramide Levels Mediated by Ampk in an In Vitro Model of Intracellular Lipid Accumulation

Authors: Yessenia L. Molina, David García-Seisdedos, Bohdan Babiy, Milagros Lerma, Javier Martínez-Botas, María J. Casarejos, María T. Vallejo, Diego Gómez-Coronado, Miguel A. Lasunción, Óscar Pastor, Rebeca Busto

Source: Biomedicines, Vol 10, Iss 6, p 1316 (2022)

Subject Terms: rottlerin, exosome/microvesicle, intracellular lipid trafficking, ceramide, sphingolipid, lysosomal storage disease, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://www.mdpi.com/2227-9059/10/6/1316; https://doaj.org/toc/2227-9059

Access URL: https://doaj.org/article/c4a8ae005cca432399f9442792dac2a4

Smart Data for Genomic Information Systems: the SILE Method

Authors: Ana León Palacio, Óscar Pastor López

Source: Complex Systems Informatics and Modeling Quarterly, Vol 0, Iss 17, Pp 1-23 (2018)

Subject Terms: Conceptual Modelling, Data Quality, Big Data, Smart Data, Genomics, Information technology, T58.5-58.64

File Description: electronic resource

Relation: https://csimq-journals.rtu.lv/article/view/2524; https://doaj.org/toc/2255-9922

Access URL: https://doaj.org/article/2b278f2271814f52a41d57803de06dd0

Selected Topics on Business Informatics: Editorial Introduction to Issue 13 of CSIMQ

Authors: Jelena Zdravkovic, Óscar Pastor, Peri Loucopoulos

Source: Complex Systems Informatics and Modeling Quarterly, Vol 0, Iss 13 (2017)

Subject Terms: Capacity planning, enterprise applications, collaborative filtering, rating time clusters, product-cost optimization, individual process model, information logistics, business process, data-centric, adaptive case management, Information technology, T58.5-58.64

File Description: electronic resource

Relation: https://csimq-journals.rtu.lv/article/view/1909; https://doaj.org/toc/2255-9922

Access URL: https://doaj.org/article/9a6c08a5c8ee411db6cd827e39844376

Selected Topics on Advances in Capability-Oriented Information Systems Development: Editorial Introduction to Issue 10 of CSIMQ

Authors: Jelena Zdravkovic, Óscar Pastor, Peri Loucopoulos

Source: Complex Systems Informatics and Modeling Quarterly, Vol 0, Iss 10 (2017)

Subject Terms: Capability, information systems engineering, business engineering, software-service bundle, capability modeling, capability design, Capability Driven Development, start-up incubation, service, ecosystem, Information technology, T58.5-58.64

File Description: electronic resource

Relation: https://csimq-journals.rtu.lv/article/view/1688; https://doaj.org/toc/2255-9922

Access URL: https://doaj.org/article/9f279951de1f4c20b207b585a8569e5c

Atypical antipsychotics alter cholesterol and fatty acid metabolism in vitro[S]

Authors: Alberto Canfrán-Duque, María E. Casado, Óscar Pastor, Jana Sánchez-Wandelmer, Gema de la Peña, Milagros Lerma, Paloma Mariscal, Franz Bracher, Miguel A. Lasunción, Rebeca Busto

Source: Journal of Lipid Research, Vol 54, Iss 2, Pp 310-324 (2013)

Subject Terms: second-generation antipsychotic drugs, cholesterol biosynthesis, lipid synthesis, apolipoprotein B secretion, intracellular lipid traffic, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S002222752042797X; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/a12cdca81f4a47f9b1e6b0c7c073b42d

A Method to Identify Relevant Genome Data: Conceptual Modeling for the Medicine of Precision
Conceptual modeling (International conference)

Authors: Palacio, Ana León, López, Óscar Pastor, Ródenas, Juan Carlos Casamayor

Source: Lecture notes in computer science. 11157:597-609

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN604317329&indx=1&recIds=ETOCCN604317329

Guidelines for Designing User Interfaces to Analyze Genetic Data. Case of Study: GenDomus
Evaluation of novel approaches to software engineering (International conference)

Authors: Iñiguez-Jarrín, Carlos, Alberto García, S., Román, José F. Reyes, López, Óscar Pastor

Source: Communications in computer and information science. 866:3-22

Availability: http://explore.bl.uk/primo_library/libweb/action/display.do?tabs=detailsTab&gathStatTab=true&ct=display&fn=search&doc=ETOCCN603976093&indx=1&recIds=ETOCCN603976093

CardioGraph: a platform to study variations associated with familiar cardiopathies

Authors: Alberto García S., Mireia Costa, Ana Perez, Oscar Pastor

Source: BMC Medical Informatics and Decision Making, Vol 23, Iss S3, Pp 1-25 (2024)

Subject Terms: Familiar cardiopathies, Novel variations, Knowledge representation, Conceptual modeling, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6947

Access URL: https://doaj.org/article/97c6438e5ef9462991aa7ebe4c03abd2

Modelling Quantum Software

Authors: Luis Mariano Bibbo, Alejandro Fernandez, José Manuel Suarez, Oscar Pastor

Source: Memoria Investigaciones en Ingeniería, Iss 27 (2024)

Subject Terms: Quantum Software Engineering, Quantum Computing, Quantum Modelling, Quantum Design, Technology, Engineering (General). Civil engineering (General), TA1-2040

File Description: electronic resource

Relation: http://revistas.um.edu.uy/index.php/ingenieria/article/view/1431; https://doaj.org/toc/2301-1092; https://doaj.org/toc/2301-1106

Access URL: https://doaj.org/article/008aa591ba384c3187e8c07cfcae6f40

CO138 - DESARROLLO DE UN SISTEMA DE INFORMACIÓN (SI) INTELIGENTE PARA UNA GESTIÓN INTEGRAL DE LOS PROCESOS DE MEDICINA NUCLEAR Y RADIOFARMACIA

Authors: Gelo, Carles Siscar, Arevshatyan, Sipan, Reyes, José Fabián, Tarazona, Alejandra Abella, Mansanet, Maria del Carmen Plancha, Ojeda, Maria Dolores Reyes, Calabuig, Laura Casas, López, Oscar Pastor, Calabuig, Elisa Caballero

Source: In Revista Española de Medicina Nuclear e Imagen Molecular May 2023 42 Supplement 1:S279-S279

CO137 - INFORME ESTRUCTURADO DE LA IMAGEN PET/CT CON 18F-FDG EN CÁNCER DE PULMÓN

Authors: Sánchez, Pedro Abreu, Lahiguera, Rubén Quintanilla, Gelo, Carles Siscar, Román, José Fabian Reyes, de la Cruz, Miguel Ángel Navas, Dólera, Tomás Mut, Muñoz, David Balaguer, López, Oscar Pastor, Calabuig, Elisa Caballero

Source: In Revista Española de Medicina Nuclear e Imagen Molecular May 2023 42 Supplement 1:S278-S278

Model Transformations Used in IT Project Initial Phases: Systematic Literature Review

Authors: Oksana Nikiforova, Kristaps Babris, Uldis Karlovs-Karlovskis, Marta Narigina, Andrejs Romanovs, Anita Jansone, Janis Grabis, Oscar Pastor

Source: Computers, Vol 14, Iss 2, p 40 (2025)

Subject Terms: IT project, model transformation, model-driven development, project inception, project elaboration, systematic literature review, Electronic computers. Computer science, QA75.5-76.95

File Description: electronic resource

Relation: https://www.mdpi.com/2073-431X/14/2/40; https://doaj.org/toc/2073-431X

Access URL: https://doaj.org/article/d91d937a77ba458480ceec9f1fad989d

The consequences of data dispersion in genomics: a comparative analysis of data sources for precision medicine

Authors: Mireia Costa, Alberto García S., Oscar Pastor

Source: BMC Medical Informatics and Decision Making, Vol 23, Iss S3, Pp 1-17 (2023)

Subject Terms: Precision medicine, DNA variations, Concordance, Completeness, Genomic data sources, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://doaj.org/toc/1472-6947

Access URL: https://doaj.org/article/51223c91404a4463b1ded77e4e042221

Conceptual modelling for life sciences based on systemist foundations

Authors: Roman Lukyanenko, Veda C. Storey, Oscar Pastor

Source: BMC Bioinformatics, Vol 23, Iss S11, Pp 1-27 (2023)

Subject Terms: Systemist perspective, Systems, Life sciences, Conceptual modelling, Systems modelling, System composition diagram, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/7e0ed5313e624524be58c42b5b5b760b

Intravenous Ascorbic Acid for the Prevention of Postreperfusion Syndrome in Orthotopic Liver Transplantation: Protocol for a Randomized Controlled Trial

Authors: Luis Gajate, Inés de la Hoz, Mercedes Espiño, Maria del Carmen Martin Gonzalez, Cristina Fernandez Martin, Ascensión Martín-Grande, Diego Parise Roux, Oscar Pastor, Judith Villahoz, Miguel Ángel Rodriguez-Gandía, Javier Nuño Vazquez

Source: JMIR Research Protocols, Vol 12, p e50091 (2023)

Subject Terms: Medicine, Computer applications to medicine. Medical informatics, R858-859.7

File Description: electronic resource

Relation: https://www.researchprotocols.org/2023/1/e50091; https://doaj.org/toc/1929-0748

Access URL: https://doaj.org/article/82fcc42cb5d947ab98bae1fe46e01a6f

Semantic interoperability: ontological unpacking of a viral conceptual model

Authors: Anna Bernasconi, Giancarlo Guizzardi, Oscar Pastor, Veda C. Storey

Source: BMC Bioinformatics, Vol 23, Iss S11, Pp 1-22 (2022)

Subject Terms: Ontological analysis, Conceptual modeling, OntoUML, COVID-19, SARS-CoV-2, Viral genome, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/5234b25b416a4eb6abb942c61935d434

The challenge of managing the evolution of genomics data over time: a conceptual model-based approach

Authors: Alberto García S., Mireia Costa, Ana Leon, Oscar Pastor

Source: BMC Bioinformatics, Vol 23, Iss S11, Pp 1-32 (2022)

Subject Terms: Bioinformatics, Temporal dimension, Conceptual models, SILE method, DELFOS oracle, Computer applications to medicine. Medical informatics, R858-859.7, Biology (General), QH301-705.5

File Description: electronic resource

Relation: https://doaj.org/toc/1471-2105

Access URL: https://doaj.org/article/b6a5c1c899e143518c2df2e5ea160527

Ellagic acid and its metabolites urolithins A/B ameliorate most common disease phenotypes in cellular and mouse models for lysosomal storage disorders by enhancing extracellular vesicle secretion

Authors: Beatriz Soto-Huelin, Bohdan Babiy, Oscar Pastor, Mario Díaz-García, Ana Toledano-Zaragoza, María Dolores Frutos, Juan Carlos Espín, Francisco A. Tomás-Barberán, Rebeca Busto, María Dolores Ledesma

Source: Neurobiology of Disease, Vol 182, Iss , Pp 106141- (2023)

Subject Terms: Extracellular vesicles, Polyphenols, Lysosomal storage disorders, Niemann pick, Brain, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996123001559; https://doaj.org/toc/1095-953X

Access URL: https://doaj.org/article/41ec54e488d340289457ccc81c47e41e

Challenges for Model-Driven Development of Strategically Aligned Information Systems

Authors: Rene Noel, Jose Ignacio Panach, Oscar Pastor

Source: IEEE Access, Vol 10, Pp 38237-38253 (2022)

Subject Terms: Model-driven development, requirements engineering, organisational modelling, Electrical engineering. Electronics. Nuclear engineering, TK1-9971

File Description: electronic resource

Relation: https://ieeexplore.ieee.org/document/9748104/; https://doaj.org/toc/2169-3536

Access URL: https://doaj.org/article/71f0ccc5531449b281311a205ef43d88

Plasma Fatty Acid Composition, Oxidative and Inflammatory Status, and Adherence to the Mediterranean Diet of Patients with Non-Alcoholic Fatty Liver Disease

Authors: Margalida Monserrat-Mesquida, Maria Magdalena Quetglas-Llabrés, Cristina Bouzas, Oscar Pastor, Lucía Ugarriza, Isabel Llompart, Karla Cevallos-Ibarra, Antoni Sureda, Josep A. Tur

Source: Antioxidants, Vol 12, Iss 8, p 1554 (2023)

Subject Terms: hepatic steatosis, Mediterranean diet, fatty acids, inflammation, ultra-processed foods, Therapeutics. Pharmacology, RM1-950

File Description: electronic resource

Relation: https://www.mdpi.com/2076-3921/12/8/1554; https://doaj.org/toc/2076-3921

Access URL: https://doaj.org/article/aa05bfc2810448eeaf79092abaa73199