Redefining the treatment of Chagas disease: a review of recent clinical and pharmacological data for a novel formulation of nifurtimox.

Authors: Jaime Altcheh, Ulrike Grossmann, Heino Stass, Martin Springsklee, Facundo Garcia-Bournissen

Source: PLoS Neglected Tropical Diseases, Vol 19, Iss 2, p e0012849 (2025)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/a9411b07a1d541079ce730b39b7036f2

Chagas disease treatment efficacy markers: experiences from a Phase III study with nifurtimox in children

Authors: Ulrike Grossmann, Maria-Luisa Rodriguez

Source: Frontiers in Parasitology, Vol 2 (2023)

Subject Terms: Chagas disease, pediatric patients, nifurtimox, ELISA, IHA, qPCR, Infectious and parasitic diseases, RC109-216

File Description: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fpara.2023.1229467/full; https://doaj.org/toc/2813-2424

Access URL: https://doaj.org/article/581482a7b8ea4459b698dcde3910b82f

ELISA F29 -A therapeutic efficacy biomarker in Chagas disease: Evaluation in pediatric patients treated with nifurtimox and followed for 4 years post-treatment.

Authors: Rocio Rivero, Mónica Inés Esteva, Erya Huang, Leylen Colmegna, Jaime Altcheh, Ulrike Grossmann, Andrés Mariano Ruiz, CHICO and CHICO SECURE Study Groups

Source: PLoS Neglected Tropical Diseases, Vol 17, Iss 6, p e0011440 (2023)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/9a0ee13271994761b4d8354ed12dad65

Serological response to nifurtimox in adult patients with chronic Chagas disease: An observational comparative study in Argentina.

Authors: David Vizcaya, Ulrike Grossmann, Frank Kleinjung, Ruiping Zhang, Kiliana Suzart-Woischnik, Sandra Seu, Teresa Ramirez, Leylen Colmegna, Oscar Ledesma

Source: PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009801 (2021)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/b9ff130976f94220896c44b0b54ff4c0

Prospective, historically controlled study to evaluate the efficacy and safety of a new paediatric formulation of nifurtimox in children aged 0 to 17 years with Chagas disease one year after treatment (CHICO).

Authors: Jaime Altcheh, Luis Castro, Juan C Dib, Ulrike Grossmann, Erya Huang, Guillermo Moscatelli, Jimy José Pinto Rocha, Teresa Estela Ramírez, CHICO Study Group

Source: PLoS Neglected Tropical Diseases, Vol 15, Iss 1, p e0008912 (2021)

Subject Terms: Arctic medicine. Tropical medicine, RC955-962, Public aspects of medicine, RA1-1270

File Description: electronic resource

Relation: https://doaj.org/toc/1935-2727; https://doaj.org/toc/1935-2735

Access URL: https://doaj.org/article/1dcc32d8cefc4129bba991b7e817b145