Exploratory analysis to predict pneumonitis during durvalumab consolidation therapy for patients with locally advanced non‐small cell lung cancer from proteomic profiling of circulating extracellular vesicles

Authors: Masahiro Torasawa, Hidehito Horinouchi, Shigehiro Yagishita, Hirofumi Utsumi, Keitaro Okuda, Daisuke Takekoshi, Saburo Ito, Hiroshi Wakui, Saori Murata, Sawako Kaku, Kae Okuma, Yuji Matsumoto, Yuki Shinno, Yusuke Okuma, Tatsuya Yoshida, Yasushi Goto, Noboru Yamamoto, Jun Araya, Yuichiro Ohe, Yu Fujita

Source: Thoracic Cancer, Vol 14, Iss 29, Pp 2909-2923 (2023)

Subject Terms: chemoradiotherapy, durvalumab, extracellular vesicles, pneumonitis, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

File Description: electronic resource

Relation: https://doaj.org/toc/1759-7706; https://doaj.org/toc/1759-7714

Access URL: https://doaj.org/article/c26bd9ec8eaf4da5b06f23bbc99b43dc

Involvement of Parkin‐mediated mitophagy in the pathogenesis of chronic obstructive pulmonary disease‐related sarcopenia

Authors: Akihiko Ito, Mitsuo Hashimoto, Jun Tanihata, Sachi Matsubayashi, Ryoko Sasaki, Shota Fujimoto, Hironori Kawamoto, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Yu Fujita, Daisuke Takekoshi, Sabro Ito, Shunsuke Minagawa, Takanori Numata, Hiromichi Hara, Tatsuki Matsuoka, Jun Udaka, Jun Araya, Mitsuru Saito, Kazuyoshi Kuwano

Source: Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1864-1882 (2022)

Subject Terms: COPD, Parkin, Muscle atrophy, Cigarette smoke, Muscle contraction, Diseases of the musculoskeletal system, RC925-935, Human anatomy, QM1-695

File Description: electronic resource

Relation: https://doaj.org/toc/2190-5991; https://doaj.org/toc/2190-6009

Access URL: https://doaj.org/article/ad895a5d387e4cd6855dea08a616154a

Possible relationship between esophageal dilatation and severity of M. abscessus pulmonary disease.

Authors: Hiromichi Hara, Keitaro Okuda, Jun Araya, Hirofumi Utsumi, Daisuke Takekoshi, Saburo Ito, Hiroshi Wakui, Shunsuke Minagawa, Takanori Numata, Kazuyoshi Kuwano

Source: PLoS ONE, Vol 16, Iss 12, p e0261866 (2021)

Subject Terms: Medicine, Science

File Description: electronic resource

Relation: https://doaj.org/toc/1932-6203

Access URL: https://doaj.org/article/bcbcf424e87046ddbd4b10b74153fd55

Inhibition of serine palmitoyltransferase delays the onset of radiation-induced pulmonary fibrosis through the negative regulation of sphingosine kinase-1 expression[S]

Authors: Irina Gorshkova, Tong Zhou, Biji Mathew, Jeffrey R. Jacobson, Daisuke Takekoshi, Palash Bhattacharya, Brett Smith, Bulent Aydogan, Ralph R. Weichselbaum, Viswanathan Natarajan, Joe G.N. Garcia, Evgeny V. Berdyshev

Source: Journal of Lipid Research, Vol 53, Iss 8, Pp 1553-1568 (2012)

Subject Terms: sphingosine-1-phospate, dihydrosphingosine-1-phosphate, myriocin, Biochemistry, QD415-436

File Description: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520418590; https://doaj.org/toc/0022-2275

Access URL: https://doaj.org/article/51f1dd75cab0445c9c1f5a09c28aed9c

Analysis of Aberrant Splicing Events and Gene Expression Outliers in Primary Ciliary Dyskinesia.

Authors: Minako Hijikata, Kozo Morimoto, Daisuke Takekoshi, Masafumi Shimoda, Keiko Wakabayashi, Akiko Miyabayashi, Tz-Chun Guo, Hiroyuki Yamada, Naoto Keicho

Source: American Journal of Respiratory Cell & Molecular Biology; Jun2023, Vol. 68 Issue 6, p702-705, 43p

Aspiration of Cerebrospinal Fluid Rhinorrhea as a Cause of Non-resolving Pneumonia.

Authors: Daisuke Takekoshi, Shun Inukai, Satoki Hatano, Shota Fujimoto, Tsukasa Kadota, Teppei Takeda, Kazuhiro Omura, Eri Mori, Jun Araya, Kazuyoshi Kuwano

Source: Internal Medicine; 2022, Vol. 61 Issue 12, p1877-1880, 4p

Chaperone-Mediated Autophagy Suppresses Apoptosis via Regulation of the Unfolded Protein Response during Chronic Obstructive Pulmonary Disease Pathogenesis.

Authors: Yusuke Hosaka, Jun Araya, Yu Fujita, Tsukasa Kadota, Kazuya Tsubouchi, Masahiro Yoshida, Shunsuke Minagawa, Hiromichi Hara, Hironori Kawamoto, Naoaki Watanabe, Akihiko Ito, Akihiro Ichikawa, Nayuta Saito, Keitaro Okuda, Junko Watanabe, Daisuke Takekoshi, Hirofumi Utsumi, Mitsuo Hashimoto, Hiroshi Wakui, Saburo Ito

Source: Journal of Immunology; Sep2020, Vol. 205 Issue 5, p1256-1267, 12p

Biomarker-based detection of asthma-COPD overlap syndrome in COPD populations.

Authors: Tsutomu Tamada, Hisatoshi Sugiura, Tsuneyuki Takahashi, Kazuto Matsunaga, Keiji Kimura, Uichiro Katsumata, Daisuke Takekoshi, Toshiaki Kikuchi, Ken Ohta, Masakazu Ichinose

Source: International Journal of COPD; 10/8/2015, p2169-2176, 8p